8C58

CpG specific M.MpeI methyltransferase crystallized in the presence of 5-hydroxycytosine and 5-methylcytosine containing dsDNA

Summary for 8C58

• Entry DOI: 10.2210/pdb8c58/pdb
• Related: 4DA4 4DKJ 8C56 8C57 8C59
• Descriptor: Cytosine-specific methyltransferase, DNA (5'-D(*CP*CP*AP*CP*AP*TP*GP*(5OC)P*GP*CP*TP*GP*AP*A)-3'), DNA (5'-D(*GP*TP*TP*CP*AP*GP*(5CM)P*GP*CP*AP*TP*GP*TP*G)-3'), ... (7 entities in total)
• Functional Keywords: m.mpei, dna methyltransferase, dna, 5-methylcytosine, 5-hydroxycytosine, 5mc, 5ohc, cpg, transferase
• Biological source: Malacoplasma penetrans HF-2; More
• Total number of polymer chains: 3
• Total formula weight: 56025.75

Authors

Wojciechowski, M.,Czapinska, H.,Krwawicz, J.,Rafalski, D.,Bochtler, M. (deposition date: 2023-01-06, release date: 2024-01-17)

• Primary citation: Wojciechowski, M.,Czapinska, H.,Krwawicz, J.,Rafalski, D.,Bochtler, M.; Cytosine analogues as DNA methyltransferase substrates and inhibitors; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.85 Å)