5E5X
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![BU of 5e5x by Molmil](/molmil-images/mine/5e5x) | |
4B62
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![BU of 4b62 by Molmil](/molmil-images/mine/4b62) | The structure of the cell wall anchor of the T6SS from Pseudomonas aeruginosa | Descriptor: | 1,2-ETHANEDIOL, PHOSPHATE ION, TSSL1 | Authors: | Robb, C.S, Carlson, M, Nano, F.E, Boraston, A.B. | Deposit date: | 2012-08-08 | Release date: | 2013-10-02 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Crystal Structure of the Periplasmic Peptidoglycan Binding Anchor of a T6Ss from Pseudomonas Aeruginosa. To be Published
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3ZHN
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![BU of 3zhn by Molmil](/molmil-images/mine/3zhn) | Crystal structure of the T6SS lipoprotein TssJ1 from Pseudomonas aeruginosa | Descriptor: | IODIDE ION, PA_0080 | Authors: | Robb, C.S, Assmus, M, Nano, F.E, Boraston, A.B. | Deposit date: | 2012-12-22 | Release date: | 2013-06-12 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structure of the T6Ss Lipoprotein Tssj1 from Pseudomonas Aeruginosa. Acta Crystallogr.,Sect.F, 69, 2013
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4B29
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![BU of 4b29 by Molmil](/molmil-images/mine/4b29) | Crystal structures of DMSP lyases RdDddP and RnDddQII | Descriptor: | 1,2-ETHANEDIOL, BROMIDE ION, DIMETHYLSULFONIOPROPIONATE LYASE, ... | Authors: | Hehemann, J.H, Law, A, Redecke, L, Boraston, A.B. | Deposit date: | 2012-07-12 | Release date: | 2012-07-25 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Crystal Structures of Dmsp Lyases Rddddp and Rndddqii To be Published
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4C22
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![BU of 4c22 by Molmil](/molmil-images/mine/4c22) | L-Fucose Isomerase In Complex With Fuculose | Descriptor: | 1,2-ETHANEDIOL, L-FUCOSE ISOMERASE, L-Fuculose open form, ... | Authors: | Higgins, M.A, Suits, M.D.L, Marsters, C, Boraston, A.B. | Deposit date: | 2013-08-16 | Release date: | 2013-12-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural and Functional Analysis of Fucose-Processing Enzymes from Streptococcus Pneumoniae. J.Mol.Biol., 426, 2014
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4BQ4
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![BU of 4bq4 by Molmil](/molmil-images/mine/4bq4) | Structural analysis of an exo-beta-agarase | Descriptor: | 3,6-anhydro-alpha-L-galactopyranose-(1-3)-beta-D-galactopyranose-(1-4)-3,6-anhydro-alpha-L-galactopyranose-(1-3)-beta-D-galactopyranose, B-AGARASE, CALCIUM ION, ... | Authors: | Pluvinage, B, Hehemann, J.H, Boraston, A.B. | Deposit date: | 2013-05-29 | Release date: | 2013-08-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Substrate Recognition and Hydrolysis by a Family 50 Exo-Beta-Agarase Aga50D from the Marine Bacterium Saccharophagus Degradans J.Biol.Chem., 288, 2013
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4C1S
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![BU of 4c1s by Molmil](/molmil-images/mine/4c1s) | Glycoside hydrolase family 76 (mannosidase) Bt3792 from Bacteroides thetaiotaomicron VPI-5482 | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, GLYCOSIDE HYDROLASE FAMILY 76 MANNOSIDASE | Authors: | Cuskin, F, Lowe, E.C, Zhu, Y, Temple, M, Thompson, A.J, Cartmell, A, Piens, K, Bracke, D, Vervecken, W, Munoz-Munoz, J.L, Suits, M.D.L, Boraston, A.B, Williams, S.J, Davies, G.J, Abbott, W.D, Martens, E.C, Gilbert, H.J. | Deposit date: | 2013-08-13 | Release date: | 2013-11-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Human Gut Bacteroidetes Can Utilize Yeast Mannan Through a Selfish Mechanism. Nature, 517, 2015
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4MCN
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![BU of 4mcn by Molmil](/molmil-images/mine/4mcn) | Human SOD1 C57S Mutant, Metal-free | Descriptor: | SULFATE ION, Superoxide dismutase [Cu-Zn] | Authors: | Sea, K, Sohn, S.H, Durazo, A, Sheng, Y, Shaw, B, Cao, X, Taylor, A.B, Whitson, L.J, Holloway, S.P, Hart, P.J, Cabelli, D.E, Gralla, E.B, Valentine, J.S. | Deposit date: | 2013-08-21 | Release date: | 2014-08-27 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Insights into the role of the unusual disulfide bond in copper-zinc superoxide dismutase. J.Biol.Chem., 290, 2015
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4L19
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![BU of 4l19 by Molmil](/molmil-images/mine/4l19) | Matrix metalloproteinase-13 complexed with selective inhibitor compound Q1 | Descriptor: | 2-[(4-methylbenzyl)sulfanyl]-3,5,6,7-tetrahydro-4H-cyclopenta[d]pyrimidin-4-one, CALCIUM ION, Collagenase 3, ... | Authors: | Minond, D, Spicer, T.P, Jiang, J, Taylor, A.B, Hart, P.J, Roush, W.R, Fields, G.B, Hodder, P.S. | Deposit date: | 2013-06-02 | Release date: | 2014-12-10 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Characterization of selective exosite-binding inhibitors of matrix metalloproteinase 13 that prevent articular cartilage degradation in vitro. J.Med.Chem., 57, 2014
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4L1L
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![BU of 4l1l by Molmil](/molmil-images/mine/4l1l) | Rat PKC C2 domain bound to CD | Descriptor: | CADMIUM ION, Protein kinase C alpha type, SULFATE ION | Authors: | Morales, K.M, Yang, Y, Long, Z, Li, P, Taylor, A.B, Hart, P.J, Igumenova, T.I. | Deposit date: | 2013-06-03 | Release date: | 2013-08-28 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Cd(2+) as a ca(2+) surrogate in protein-membrane interactions: isostructural but not isofunctional. J.Am.Chem.Soc., 135, 2013
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4NHH
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![BU of 4nhh by Molmil](/molmil-images/mine/4nhh) | Structure of 2G12 IgG Dimer | Descriptor: | 2G12 IgG dimer heavy chain, 2G12 IgG dimer light chain, Hepatitis B virus receptor binding protein | Authors: | Wu, Y, West Jr, A.P, Kim, H.J, Thornton, M.E, Ward, A.B, Bjorkman, P.J. | Deposit date: | 2013-11-05 | Release date: | 2014-02-26 | Method: | X-RAY DIFFRACTION (6.5 Å) | Cite: | Structural basis for enhanced HIV-1 neutralization by a dimeric immunoglobulin G form of the glycan-recognizing antibody 2G12. Cell Rep, 5, 2013
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8SW7
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![BU of 8sw7 by Molmil](/molmil-images/mine/8sw7) | BG505 Boost2 SOSIP.664 in complex with NHP polyclonal antibody FP1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 Boost 2 gp120, BG505 Boost 2 gp41, ... | Authors: | Pratap, P.P, Antansijevic, A, Ozorowski, G, Ward, A.B. | Deposit date: | 2023-05-17 | Release date: | 2023-07-26 | Method: | ELECTRON MICROSCOPY (3.37 Å) | Cite: | Focusing antibody responses to the fusion peptide in rhesus macaques. Biorxiv, 2023
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4O3Y
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![BU of 4o3y by Molmil](/molmil-images/mine/4o3y) | Crystal structure of the vaccine antigen Transferrin Binding Protein B (TbpB) mutant Arg-179-Glu from Actinobacillus pleuropneumoniae H87 | Descriptor: | ACETATE ION, GLYCEROL, Outer membrane protein; transferrin-binding protein | Authors: | Calmettes, C, Yu, R.H, Schryvers, A.B, Moraes, T.F. | Deposit date: | 2013-12-18 | Release date: | 2015-01-14 | Last modified: | 2015-03-04 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Nonbinding site-directed mutants of transferrin binding protein B exhibit enhanced immunogenicity and protective capabilities. Infect.Immun., 83, 2015
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4O4X
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![BU of 4o4x by Molmil](/molmil-images/mine/4o4x) | Crystal structure of the vaccine antigen Transferrin Binding Protein B (TbpB) double mutant Tyr-167-Ala and Trp-176-Ala from Haemophilus parasuis Hp5 | Descriptor: | GLYCEROL, SODIUM ION, SULFATE ION, ... | Authors: | Calmettes, C, Yu, R.H, Schryvers, A.B, Moraes, T.F. | Deposit date: | 2013-12-19 | Release date: | 2015-01-14 | Last modified: | 2015-03-04 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Nonbinding site-directed mutants of transferrin binding protein B exhibit enhanced immunogenicity and protective capabilities. Infect.Immun., 83, 2015
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8T57
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![BU of 8t57 by Molmil](/molmil-images/mine/8t57) | Structure of mechanically activated ion channel OSCA2.3 in peptidiscs | Descriptor: | CHOLESTEROL, CSC1-like protein HYP1, PALMITIC ACID | Authors: | Jojoa-Cruz, S, Burendei, B, Lee, W.H, Ward, A.B. | Deposit date: | 2023-06-12 | Release date: | 2023-12-27 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structure of mechanically activated ion channel OSCA2.3 reveals mobile elements in the transmembrane domain. Structure, 32, 2024
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4NCO
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![BU of 4nco by Molmil](/molmil-images/mine/4nco) | Crystal Structure of the BG505 SOSIP gp140 HIV-1 Env trimer in Complex with the Broadly Neutralizing Fab PGT122 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP gp120, BG505 SOSIP gp41, ... | Authors: | Julien, J.-P, Stanfield, R.L, Lyumkis, D, Ward, A.B, Wilson, I.A. | Deposit date: | 2013-10-24 | Release date: | 2013-11-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (4.7 Å) | Cite: | Crystal structure of a soluble cleaved HIV-1 envelope trimer. Science, 342, 2013
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8T56
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![BU of 8t56 by Molmil](/molmil-images/mine/8t56) | Structure of mechanically activated ion channel OSCA1.2 in peptidiscs | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, CHOLESTEROL, CHOLESTEROL HEMISUCCINATE, ... | Authors: | Burendei, B, Jojoa-Cruz, S, Lee, W.H, Ward, A.B. | Deposit date: | 2023-06-12 | Release date: | 2023-12-27 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structure of mechanically activated ion channel OSCA2.3 reveals mobile elements in the transmembrane domain. Structure, 32, 2024
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4NHG
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![BU of 4nhg by Molmil](/molmil-images/mine/4nhg) | Crystal Structure of 2G12 IgG Dimer | Descriptor: | 2G12 IgG dimer heavy chain, 2G12 IgG dimer light chain, Hepatitis B virus receptor binding protein | Authors: | Wu, Y, West Jr, A.P, Kim, H.J, Thornton, M.E, Ward, A.B, Bjorkman, P.J. | Deposit date: | 2013-11-05 | Release date: | 2014-02-26 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (8.001 Å) | Cite: | Structural basis for enhanced HIV-1 neutralization by a dimeric immunoglobulin G form of the glycan-recognizing antibody 2G12. Cell Rep, 5, 2013
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4O3Z
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![BU of 4o3z by Molmil](/molmil-images/mine/4o3z) | Crystal structure of the vaccine antigen Transferrin Binding Protein B (TbpB) mutant Tyr-95-Ala from Actinobacillus pleuropneumoniae H87 | Descriptor: | ACETATE ION, GLYCEROL, Outer membrane protein; transferrin-binding protein | Authors: | Calmettes, C, Yu, R.H, Schryvers, A.B, Moraes, T.F. | Deposit date: | 2013-12-18 | Release date: | 2015-01-14 | Last modified: | 2015-03-04 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Nonbinding site-directed mutants of transferrin binding protein B exhibit enhanced immunogenicity and protective capabilities. Infect.Immun., 83, 2015
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4MWB
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![BU of 4mwb by Molmil](/molmil-images/mine/4mwb) | Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-(3-{[(2,5-dichlorothiophen-3-yl)methyl]amino}propyl)-3-thiophen-3-ylurea (Chem 1509) | Descriptor: | 1-(3-{[(2,5-dichlorothiophen-3-yl)methyl]amino}propyl)-3-thiophen-3-ylurea, DIMETHYL SULFOXIDE, GLYCEROL, ... | Authors: | Koh, C.Y, Kim, J.E, Wetzel, A.B, de van der Schueren, W.J, Shibata, S, Liu, J, Zhang, Z, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J. | Deposit date: | 2013-09-24 | Release date: | 2014-04-30 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.313 Å) | Cite: | Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness. Plos Negl Trop Dis, 8, 2014
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4MUB
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![BU of 4mub by Molmil](/molmil-images/mine/4mub) | Schistosoma mansoni (Blood Fluke) Sulfotransferase/Oxamniquine Complex | Descriptor: | ADENOSINE-3'-5'-DIPHOSPHATE, Sulfotransferase, {(2S)-7-nitro-2-[(propan-2-ylamino)methyl]-1,2,3,4-tetrahydroquinolin-6-yl}methanol | Authors: | Valentim, C.L.L, Cioli, D, Chevalier, F.D, Cao, X, Taylor, A.B, Holloway, S.P, Pica-Mattoccia, L, Guidi, A, Basso, A, Tsai, I.J, Berriman, M, Carvalho-Queiroz, C, Almeida, M, Aguilar, H, Frantz, D.E, Hart, P.J, Anderson, T.J.C, LoVerde, P.T. | Deposit date: | 2013-09-21 | Release date: | 2013-12-18 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Genetic and molecular basis of drug resistance and species-specific drug action in schistosome parasites. Science, 342, 2013
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8T4D
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![BU of 8t4d by Molmil](/molmil-images/mine/8t4d) | MD65 N332-GT5 SOSIP in complex with RM_N332_08 Fab and RM20A3 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MD65 N332-GT5 SOSIP gp120, ... | Authors: | Ozorowski, G, Torres, J.L, Ward, A.B. | Deposit date: | 2023-06-09 | Release date: | 2024-05-08 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Vaccine priming of rare HIV broadly neutralizing antibody precursors in nonhuman primates. Science, 384, 2024
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4MW9
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![BU of 4mw9 by Molmil](/molmil-images/mine/4mw9) | Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-{3-[(3-ethynylbenzyl)amino]propyl}-3-thiophen-3-ylurea (Chem 1478) | Descriptor: | 1-{3-[(3-ethynylbenzyl)amino]propyl}-3-thiophen-3-ylurea, DIMETHYL SULFOXIDE, GLYCEROL, ... | Authors: | Koh, C.Y, Kim, J.E, Wetzel, A.B, de van der Schueren, W.J, Shibata, S, Liu, J, Zhang, Z, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J. | Deposit date: | 2013-09-24 | Release date: | 2014-04-30 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness. Plos Negl Trop Dis, 8, 2014
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4MVX
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![BU of 4mvx by Molmil](/molmil-images/mine/4mvx) | Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-{3-[(3,5-dichlorobenzyl)amino]propyl}-3-phenylurea (Chem 1356) | Descriptor: | 1-{3-[(3,5-dichlorobenzyl)amino]propyl}-3-phenylurea, DIMETHYL SULFOXIDE, GLYCEROL, ... | Authors: | Koh, C.Y, Kim, J.E, Wetzel, A.B, de van der Schueren, W.J, Shibata, S, Liu, J, Zhang, Z, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J. | Deposit date: | 2013-09-24 | Release date: | 2014-04-30 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness. Plos Negl Trop Dis, 8, 2014
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4MWC
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![BU of 4mwc by Molmil](/molmil-images/mine/4mwc) | Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-(3-{[(2-methyl-1-benzothiophen-3-yl)methyl]amino}propyl)-3-thiophen-3-ylurea (Chem 1540) | Descriptor: | 1-(3-{[(2-methyl-1-benzothiophen-3-yl)methyl]amino}propyl)-3-thiophen-3-ylurea, DIMETHYL SULFOXIDE, GLYCEROL, ... | Authors: | Koh, C.Y, Kim, J.E, Wetzel, A.B, de van der Schueren, W.J, Shibata, S, Liu, J, Zhang, Z, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J. | Deposit date: | 2013-09-24 | Release date: | 2014-04-30 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.649 Å) | Cite: | Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness. Plos Negl Trop Dis, 8, 2014
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