4MCN
Human SOD1 C57S Mutant, Metal-free
Summary for 4MCN
Entry DOI | 10.2210/pdb4mcn/pdb |
Related | 4MCM |
Descriptor | Superoxide dismutase [Cu-Zn], SULFATE ION (3 entities in total) |
Functional Keywords | oxidoreductase, human cu, zn superoxide dismutase, antioxidant, metal-binding, amyotrophic lateral sclerosis, disulfide bond |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P00441 |
Total number of polymer chains | 2 |
Total formula weight | 31719.05 |
Authors | Sea, K.,Sohn, S.H.,Durazo, A.,Sheng, Y.,Shaw, B.,Cao, X.,Taylor, A.B.,Whitson, L.J.,Holloway, S.P.,Hart, P.J.,Cabelli, D.E.,Gralla, E.B.,Valentine, J.S. (deposition date: 2013-08-21, release date: 2014-08-27, Last modification date: 2023-09-20) |
Primary citation | Sea, K.,Sohn, S.H.,Durazo, A.,Sheng, Y.,Shaw, B.F.,Cao, X.,Taylor, A.B.,Whitson, L.J.,Holloway, S.P.,Hart, P.J.,Cabelli, D.E.,Gralla, E.B.,Valentine, J.S. Insights into the role of the unusual disulfide bond in copper-zinc superoxide dismutase. J.Biol.Chem., 290:2405-2418, 2015 Cited by PubMed: 25433341DOI: 10.1074/jbc.M114.588798 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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