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5TNM
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BU of 5tnm by Molmil
Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted (R)-1,2-Epoxyoctane hydrolysis intermediate
Descriptor: (2R)-octane-1,2-diol, CFTR inhibitory factor
Authors:Hvorecny, K.L, Madden, D.R.
Deposit date:2016-10-14
Release date:2017-10-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase.
Structure, 25, 2017
5TNI
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BU of 5tni by Molmil
Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted S-Styrene oxide hydrolysis intermediate
Descriptor: (1R)-1-phenylethane-1,2-diol, CFTR inhibitory factor
Authors:Hvorecny, K.L, Madden, D.R.
Deposit date:2016-10-14
Release date:2017-10-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase.
Structure, 25, 2017
5TNP
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BU of 5tnp by Molmil
Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted Styrene oxide hydrolysis intermediate
Descriptor: (1R)-1-phenylethane-1,2-diol, CFTR inhibitory factor
Authors:Hvorecny, K.L, Madden, D.R.
Deposit date:2016-10-14
Release date:2017-10-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase.
Structure, 25, 2017
9C66
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BU of 9c66 by Molmil
Structure of the Mena EVH1 domain bound to the polyproline segment of PTP1B
Descriptor: 1,2-ETHANEDIOL, Protein enabled homolog, SULFATE ION, ...
Authors:LaComb, L, Fedorov, E, Bonanno, J.B, Almo, S.C, Ghosh, A.
Deposit date:2024-06-07
Release date:2024-08-28
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Insights into the Interaction Landscape of the EVH1 Domain of Mena.
Biochemistry, 2024
4QN0
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BU of 4qn0 by Molmil
Crystal structure of the CPS-6 mutant Q130K
Descriptor: Endonuclease G, mitochondrial, MAGNESIUM ION
Authors:Lin, J.L.J, Yuan, H.S.
Deposit date:2014-06-17
Release date:2015-06-17
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Oxidative Stress Impairs Cell Death by Repressing the Nuclease Activity of Mitochondrial Endonuclease G
Cell Rep, 16, 2016
3NTC
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BU of 3ntc by Molmil
Crystal structure of KD-247 Fab, an anti-V3 antibody that inhibits HIV-1 Entry
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Fab heavy chain, ...
Authors:Sarafianos, S.G, Kirby, K.A.
Deposit date:2010-07-03
Release date:2010-08-25
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural basis of clade-specific HIV-1 neutralization by humanized anti-V3 monoclonal antibody KD-247.
Faseb J., 29, 2015
5TNH
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BU of 5tnh by Molmil
Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted 17,18-EpETE hydrolysis intermediate
Descriptor: (5Z,8Z,11Z,14Z,17R,18R)-17,18-dihydroxyicosa-5,8,11,14-tetraenoic acid, CFTR inhibitory factor
Authors:Hvorecny, K.L, Madden, D.R.
Deposit date:2016-10-14
Release date:2017-10-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase.
Structure, 25, 2017
5TNS
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BU of 5tns by Molmil
Crystal structure of the D129S mutant of the CFTR inhibitory factor Cif containing 1,2-Epoxycyclohexane
Descriptor: (1R,6S)-7-oxabicyclo[4.1.0]heptane, CFTR inhibitory factor
Authors:Hvorecny, K.L, Madden, D.R.
Deposit date:2016-10-14
Release date:2017-10-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase.
Structure, 25, 2017
5TNF
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BU of 5tnf by Molmil
Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted 19,20-EpDPE hydrolysis intermediate
Descriptor: (4Z,7Z,10Z,13Z,16Z,19R,20R)-19,20-dihydroxydocosa-4,7,10,13,16-pentaenoic acid, CFTR inhibitory factor
Authors:Hvorecny, K.L, Madden, D.R.
Deposit date:2016-10-14
Release date:2017-10-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase.
Structure, 25, 2017
5TNQ
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BU of 5tnq by Molmil
Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted (R)-Styrene oxide hydrolysis intermediate
Descriptor: (1R)-1-phenylethane-1,2-diol, CFTR inhibitory factor
Authors:Hvorecny, K.L, Madden, D.R.
Deposit date:2016-10-14
Release date:2017-10-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase.
Structure, 25, 2017
4IW3
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BU of 4iw3 by Molmil
Crystal structure of a Pseudomonas putida prolyl-4-hydroxylase (P4H) in complex with elongation factor Tu (EF-Tu)
Descriptor: Elongation factor Tu-A, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Scotti, J.S, McDonough, M.A, Schofield, C.J.
Deposit date:2013-01-23
Release date:2014-01-29
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.697 Å)
Cite:Human oxygen sensing may have origins in prokaryotic elongation factor Tu prolyl-hydroxylation
Proc.Natl.Acad.Sci.USA, 111, 2014
4IU2
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BU of 4iu2 by Molmil
Cohesin-dockerin -X domain complex from Ruminococcus flavefacience
Descriptor: CALCIUM ION, CHLORIDE ION, Cell-wall anchoring protein, ...
Authors:Salama-Alber, O, Bayer, E, Frolow, F.
Deposit date:2013-01-19
Release date:2013-04-24
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Atypical Cohesin-Dockerin Complex Responsible for Cell Surface Attachment of Cellulosomal Components: BINDING FIDELITY, PROMISCUITY, AND STRUCTURAL BUTTRESSES.
J.Biol.Chem., 288, 2013
4IU3
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BU of 4iu3 by Molmil
Cohesin-dockerin -X domain complex from Ruminococcus flavefacience
Descriptor: CALCIUM ION, Cell-wall anchoring protein, Cellulose-binding protein, ...
Authors:Salama-Alber, O, Bayer, E, Frolow, F.
Deposit date:2013-01-19
Release date:2013-04-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Atypical Cohesin-Dockerin Complex Responsible for Cell Surface Attachment of Cellulosomal Components: BINDING FIDELITY, PROMISCUITY, AND STRUCTURAL BUTTRESSES.
J.Biol.Chem., 288, 2013
4J0Q
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BU of 4j0q by Molmil
Crystal structure of Pseudomonas putida elongation factor Tu (EF-Tu)
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Elongation factor Tu-A, ...
Authors:Scotti, J.S, McDonough, M.A, Schofield, C.J.
Deposit date:2013-01-31
Release date:2014-02-05
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.294 Å)
Cite:Human oxygen sensing may have origins in prokaryotic elongation factor Tu prolyl-hydroxylation
Proc.Natl.Acad.Sci.USA, 111, 2014
4J25
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BU of 4j25 by Molmil
Crystal structure of a Pseudomonas putida prolyl-4-hydroxylase (P4H)
Descriptor: MANGANESE (II) ION, N-OXALYLGLYCINE, Putative uncharacterized protein
Authors:Scotti, J.S, McDonough, M.A, Schofield, C.J.
Deposit date:2013-02-04
Release date:2014-02-05
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Human oxygen sensing may have origins in prokaryotic elongation factor Tu prolyl-hydroxylation
Proc.Natl.Acad.Sci.USA, 111, 2014
7YF6
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BU of 7yf6 by Molmil
Crystal structure of HIV-1 protease in complex with macrocyclic peptide
Descriptor: MAGNESIUM ION, Macrocyclic Peptide, Protease
Authors:Kusumoto, Y, Sato, S, Yamada, T, Kozono, I, Nakata, Z, Asada, N, Mitsuki, S, Wakasa-Morimoto, C, Tohru, M, Watanabe, A, Hayashi, K, Mikamiyama, H.
Deposit date:2022-07-07
Release date:2022-11-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Highly Potent and Oral Macrocyclic Peptides as a HIV-1 Protease Inhibitor: mRNA Display-Derived Hit-to-Lead Optimization.
Acs Med.Chem.Lett., 13, 2022
7COV
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BU of 7cov by Molmil
Potato D-enzyme, native (substrate free)
Descriptor: 4-alpha-glucanotransferase, chloroplastic/amyloplastic, CALCIUM ION, ...
Authors:Unno, H, Imamura, K.
Deposit date:2020-08-05
Release date:2020-08-26
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural analysis and reaction mechanism of the disproportionating enzyme (D-enzyme) from potato.
Protein Sci., 29, 2020
4HQQ
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BU of 4hqq by Molmil
Crystal structure of RV144-elicited antibody CH58
Descriptor: CH58 Fab heavy chain, CH58 Fab light chain
Authors:McLellan, J.S, Haynes, B.F, Kwong, P.D.
Deposit date:2012-10-25
Release date:2013-02-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2.
Immunity, 38, 2013
4GJJ
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BU of 4gjj by Molmil
Crystal structure of Pseudomonas stutzeri L-rhamnose isomerase mutant H101N in complex with D-allopyranose
Descriptor: D-ALLOSE, L-rhamnose isomerase, MANGANESE (II) ION, ...
Authors:Yoshida, H, Kamitori, S.
Deposit date:2012-08-09
Release date:2012-12-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Structure of l-rhamnose isomerase in complex with l-rhamnopyranose demonstrates the sugar-ring opening mechanism and the role of a substrate sub-binding site.
FEBS Open Bio, 3, 2013
2Z7L
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BU of 2z7l by Molmil
Unphosphorylated Mitogen Activated Protein Kinase ERK2 in Complex with (4-{[5-Carbamoyl-4-(3-Methylanilino)Pyrimidin 2-Yl]Amino}Phenyl)Acetic Acid
Descriptor: BETA-MERCAPTOETHANOL, Mitogen-activated protein kinase 1, SULFATE ION, ...
Authors:Katayama, N, Kurihara, H.
Deposit date:2007-08-27
Release date:2008-08-12
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Identification of a key element for hydrogen-bonding patterns between protein kinases and their inhibitors
Proteins, 73, 2008
2Z8C
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BU of 2z8c by Molmil
Phosphorylated insulin receptor tyrosine kinase in complex with (4-{[5-carbamoyl-4-(3-methylanilino)pyrimidin-2-yl]amino}phenyl)acetic acid
Descriptor: 6-mer peptide from Insulin receptor substrate 1, Insulin receptor, [4-({5-(AMINOCARBONYL)-4-[(3-METHYLPHENYL)AMINO]PYRIMIDIN-2-YL}AMINO)PHENYL]ACETIC ACID
Authors:Katayama, N, Kurihara, H.
Deposit date:2007-09-05
Release date:2008-08-12
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Identification of a key element for hydrogen-bonding patterns between protein kinases and their inhibitors.
Proteins, 73, 2008
4HPY
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BU of 4hpy by Molmil
Crystal structure of RV144-elicited antibody CH59 in complex with V2 peptide
Descriptor: CH59 Fab heavy chain, CH59 Fab light chain, Envelope glycoprotein gp160, ...
Authors:McLellan, J.S, Gorman, J, Haynes, B.F, Kwong, P.D.
Deposit date:2012-10-24
Release date:2013-02-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2.
Immunity, 38, 2013
4GJI
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BU of 4gji by Molmil
Crystal structure of Pseudomonas stutzeri L-rhamnose isomerase mutant H101N in complex with L-rhamnopyranose
Descriptor: L-RHAMNOSE, L-rhamnose isomerase, MANGANESE (II) ION, ...
Authors:Yoshida, H, Kamitori, S.
Deposit date:2012-08-09
Release date:2012-12-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of l-rhamnose isomerase in complex with l-rhamnopyranose demonstrates the sugar-ring opening mechanism and the role of a substrate sub-binding site.
FEBS Open Bio, 3, 2013
4HPO
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BU of 4hpo by Molmil
Crystal structure of RV144-elicited antibody CH58 in complex with V2 peptide
Descriptor: CH58 Fab heavy chain, CH58 Fab light chain, Envelope glycoprotein gp160, ...
Authors:McLellan, J.S, Gorman, J, Haynes, B.F, Kwong, P.D.
Deposit date:2012-10-24
Release date:2013-02-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.694 Å)
Cite:Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2.
Immunity, 38, 2013
8EE2
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BU of 8ee2 by Molmil
Crystal Structure of Nanobody VHH219 Bound to Its Antigen PA14 Cif
Descriptor: CFTR inhibitory factor, Nanobody VHH219
Authors:Simard, A.R, Madden, D.R.
Deposit date:2022-09-06
Release date:2023-09-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of Nanobody VHH219 Bound to Its Antigen PA14 Cif
To Be Published

224201

數據於2024-08-28公開中

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