5TNQ
Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted (R)-Styrene oxide hydrolysis intermediate
Summary for 5TNQ
Entry DOI | 10.2210/pdb5tnq/pdb |
Related | 3KD2 4DMC 5TND 5TNE 5TNF 5TNG 5TNH 5TNI 5TNJ 5TNK 5TNL 5TNM 5TNN 5TNP 5TNR 5TNS |
Descriptor | CFTR inhibitory factor, (1R)-1-phenylethane-1,2-diol (3 entities in total) |
Functional Keywords | epoxide hydrolase, hydroxyalkyl-enzyme intermediate, hydrolase |
Biological source | Pseudomonas aeruginosa (strain UCBPP-PA14) |
Total number of polymer chains | 4 |
Total formula weight | 137207.52 |
Authors | Hvorecny, K.L.,Madden, D.R. (deposition date: 2016-10-14, release date: 2017-10-11, Last modification date: 2023-10-04) |
Primary citation | Hvorecny, K.L.,Bahl, C.D.,Kitamura, S.,Lee, K.S.S.,Hammock, B.D.,Morisseau, C.,Madden, D.R. Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase. Structure, 25:697-707.e4, 2017 Cited by PubMed: 28392259DOI: 10.1016/j.str.2017.03.002 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)