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5TNQ

Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted (R)-Styrene oxide hydrolysis intermediate

Functional Information from GO Data
ChainGOidnamespacecontents
A0016787molecular_functionhydrolase activity
B0016787molecular_functionhydrolase activity
C0016787molecular_functionhydrolase activity
D0016787molecular_functionhydrolase activity
Functional Information from PDB Data
site_idAC1
Number of Residues6
Detailsbinding site for residue FEH C 401
ChainResidue
CASP129
CHIS177
CPHE178
CHIS207
CTYR239
CHIS297

site_idAC2
Number of Residues16
Detailsbinding site for Di-peptide FEH A 401 and ASP A 129
ChainResidue
AILE130
AGLY131
AILE132
AMET152
AGLN153
AALA154
AHIS177
APHE178
ATYR239
AMET272
AHIS297
AHOH512
AHOH652
AGLY62
APHE63
AHIS128

site_idAC3
Number of Residues15
Detailsbinding site for Di-peptide FEH B 401 and ASP B 129
ChainResidue
BGLY62
BPHE63
BHIS128
BILE130
BGLY131
BILE132
BMET152
BGLN153
BALA154
BHIS177
BPHE178
BHIS207
BTYR239
BHIS297
BHOH645

site_idAC4
Number of Residues14
Detailsbinding site for Di-peptide FEH D 401 and ASP D 129
ChainResidue
DGLY62
DPHE63
DHIS128
DILE130
DGLY131
DILE132
DMET152
DGLN153
DALA154
DHIS177
DPHE178
DTYR239
DHIS297
DHOH663

226707

PDB entries from 2024-10-30

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