4L1W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4l1w by Molmil](/molmil-images/mine/4l1w) | Crystal Structuer of Human 3-alpha Hydroxysteroid Dehydrogenase Type 3 in Complex with NADP+ and Progesterone | Descriptor: | Aldo-keto reductase family 1 member C2, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PROGESTERONE, ... | Authors: | Zhang, B, Hu, X.-J, Lin, S.-X. | Deposit date: | 2013-06-03 | Release date: | 2014-04-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Human 3-alpha hydroxysteroid dehydrogenase type 3 (3 alpha-HSD3): The V54L mutation restricting the steroid alternative binding and enhancing the 20 alpha-HSD activity J.Steroid Biochem.Mol.Biol., 141, 2014
|
|
4NCZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ncz by Molmil](/molmil-images/mine/4ncz) | Spermidine N-acetyltransferase from Vibrio cholerae in complex with 2-[n-cyclohexylamino]ethane sulfonate. | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, CALCIUM ION, SODIUM ION, ... | Authors: | Osipiuk, J, Zhou, M, Gu, M, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2013-10-25 | Release date: | 2013-11-06 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | A Novel Polyamine Allosteric Site of SpeG from Vibrio cholerae Is Revealed by Its Dodecameric Structure. J.Mol.Biol., 427, 2015
|
|
3RHZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3rhz by Molmil](/molmil-images/mine/3rhz) | |
5NGX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ngx by Molmil](/molmil-images/mine/5ngx) | The 1.06 A resolution structure of the L16G mutant of ferric cytochrome c prime from Alcaligenes xylosoxidans, complexed with nitrite | Descriptor: | Cytochrome c', GLYCEROL, HEME C, ... | Authors: | Strange, R, Hough, M, Kekelli, D, Horrell, S, Moreno Chicano, T. | Deposit date: | 2017-03-20 | Release date: | 2018-05-16 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.06 Å) | Cite: | Distinguishing Nitro vs Nitrito Coordination in Cytochrome c' Using Vibrational Spectroscopy and Density Functional Theory. Inorg.Chem., 56, 2017
|
|
3D4N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3d4n by Molmil](/molmil-images/mine/3d4n) | Crystal Structure of Human 11-beta-Hydroxysteroid Dehydrogenase (HSD1) in Complex with Sulfonamide Inhibitor | Descriptor: | 1-{[(3R)-3-methyl-4-({4-[(1S)-2,2,2-trifluoro-1-hydroxy-1-methylethyl]phenyl}sulfonyl)piperazin-1-yl]methyl}cyclopropanecarboxamide, Corticosteroid 11-beta-dehydrogenase isozyme 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Wang, Z, Liu, J, Sudom, A, Walker, N.P. | Deposit date: | 2008-05-14 | Release date: | 2008-07-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Discovery of Novel, Potent Benzamide Inhibitors of 11beta-Hydroxysteroid Dehydrogenase Type 1 (11beta-HSD1) Exhibiting Oral Activity in an Enzyme Inhibition ex Vivo Model J.Med.Chem., 51, 2008
|
|
6H7E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6h7e by Molmil](/molmil-images/mine/6h7e) | GEF regulatory domain | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SULFATE ION, cDNA FLJ56134, ... | Authors: | Ferrandez, Y, Cherfils, J, Peurois, F. | Deposit date: | 2018-07-31 | Release date: | 2020-02-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Membranes prime the RapGEF EPAC1 to transduce cAMP signaling. Nat Commun, 14, 2023
|
|
5N8I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5n8i by Molmil](/molmil-images/mine/5n8i) | Serial Cu nitrite reductase structures at elevated cryogenic temperature, 100K reference dataset. | Descriptor: | COPPER (II) ION, Copper-containing nitrite reductase, MALONATE ION | Authors: | Horrell, S, Kekilli, D, Hough, M, Strange, R. | Deposit date: | 2017-02-23 | Release date: | 2017-07-26 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Active-site protein dynamics and solvent accessibility in native Achromobacter cycloclastes copper nitrite reductase. IUCrJ, 4, 2017
|
|
5NC0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5nc0 by Molmil](/molmil-images/mine/5nc0) | The 0.91 A resolution structure of the L16G mutant of cytochrome c prime from Alcaligenes xylosoxidans, complexed with nitric oxide | Descriptor: | 1,2-ETHANEDIOL, Cytochrome c', HEME C, ... | Authors: | Strange, R, Hough, M, Antonyuk, S, Rustage, N. | Deposit date: | 2017-03-02 | Release date: | 2018-01-10 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (0.91 Å) | Cite: | Distinguishing Nitro vs Nitrito Coordination in Cytochrome c' Using Vibrational Spectroscopy and Density Functional Theory. Inorg Chem, 56, 2017
|
|
3ZK0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3zk0 by Molmil](/molmil-images/mine/3zk0) | |
3D3E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3d3e by Molmil](/molmil-images/mine/3d3e) | Crystal Structure of Human 11-beta-Hydroxysteroid Dehydrogenase (HSD1) in Complex with Benzamide Inhibitor | Descriptor: | Corticosteroid 11-beta-dehydrogenase isozyme 1, N-cyclopropyl-N-(trans-4-pyridin-3-ylcyclohexyl)-4-[(1S)-2,2,2-trifluoro-1-hydroxy-1-methylethyl]benzamide, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Wang, Z, Sudom, A, Liu, J, Walker, N.P. | Deposit date: | 2008-05-09 | Release date: | 2008-07-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Discovery of Novel, Potent Benzamide Inhibitors of 11beta-Hydroxysteroid Dehydrogenase Type 1 (11beta-HSD1) Exhibiting Oral Activity in an Enzyme Inhibition ex Vivo Model J.Med.Chem., 51, 2008
|
|
3ZJA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3zja by Molmil](/molmil-images/mine/3zja) | |
1YQH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1yqh by Molmil](/molmil-images/mine/1yqh) | |
1YB4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1yb4 by Molmil](/molmil-images/mine/1yb4) | Crystal Structure of the Tartronic Semialdehyde Reductase from Salmonella typhimurium LT2 | Descriptor: | tartronic semialdehyde reductase | Authors: | Kim, Y, Wu, R, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2004-12-20 | Release date: | 2005-02-01 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | X-ray crystal structure of GarR-tartronate semialdehyde reductase from Salmonella typhimurium. J Struct Funct Genomics, 10, 2009
|
|
2QUH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2quh by Molmil](/molmil-images/mine/2quh) | |
2QUJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2quj by Molmil](/molmil-images/mine/2quj) | |
2QUI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qui by Molmil](/molmil-images/mine/2qui) | |
2KFT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2kft by Molmil](/molmil-images/mine/2kft) | |
1PBN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1pbn by Molmil](/molmil-images/mine/1pbn) | PURINE NUCLEOSIDE PHOSPHORYLASE | Descriptor: | PURINE NUCLEOSIDE PHOSPHORYLASE | Authors: | Mao, C, Ealick, S.E. | Deposit date: | 1995-07-10 | Release date: | 1995-11-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Calf spleen purine nucleoside phosphorylase complexed with substrates and substrate analogues. Biochemistry, 37, 1998
|
|
2KWJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2kwj by Molmil](/molmil-images/mine/2kwj) | Solution structures of the double PHD fingers of human transcriptional protein DPF3 bound to a histone peptide containing acetylation at lysine 14 | Descriptor: | Histone peptide, ZINC ION, Zinc finger protein DPF3 | Authors: | Zeng, L, Zhang, Q, Li, S, Plotnikov, A.N, Walsh, M.J, Zhou, M. | Deposit date: | 2010-04-12 | Release date: | 2010-07-14 | Last modified: | 2023-11-15 | Method: | SOLUTION NMR | Cite: | Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b. Nature, 466, 2010
|
|
2KVM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2kvm by Molmil](/molmil-images/mine/2kvm) | |
2KWO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2kwo by Molmil](/molmil-images/mine/2kwo) | Solution structure of the double PHD (plant homeodomain) fingers of human transcriptional protein DPF3b bound to a histone H4 peptide containing N-terminal acetylation at Serine 1 | Descriptor: | Histone peptide, ZINC ION, Zinc finger protein DPF3 | Authors: | Zeng, L, Zhang, Q, Li, S, Plotnikov, A.N, Walsh, M.J, Zhou, M. | Deposit date: | 2010-04-14 | Release date: | 2010-07-14 | Last modified: | 2013-06-19 | Method: | SOLUTION NMR | Cite: | Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b. Nature, 466, 2010
|
|
2KWN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2kwn by Molmil](/molmil-images/mine/2kwn) | Solution structure of the double PHD (plant homeodomain) fingers of human transcriptional protein DPF3b bound to a histone H4 peptide containing acetylation at Lysine 16 | Descriptor: | Histone peptide, ZINC ION, Zinc finger protein DPF3 | Authors: | Zeng, L, Zhang, Q, Li, S, Plotnikov, A.N, Walsh, M.J, Zhou, M. | Deposit date: | 2010-04-13 | Release date: | 2010-07-14 | Last modified: | 2023-11-15 | Method: | SOLUTION NMR | Cite: | Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b. Nature, 466, 2010
|
|
2KWK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2kwk by Molmil](/molmil-images/mine/2kwk) | Solution structures of the double PHD fingers of human transcriptional protein DPF3b bound to a H3 peptide wild type | Descriptor: | Histone peptide, ZINC ION, Zinc finger protein DPF3 | Authors: | Zeng, L, Zhang, Q, Li, S, Plotnikov, A.N, Walsh, M.J, Zhou, M. | Deposit date: | 2010-04-12 | Release date: | 2010-07-14 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b. Nature, 466, 2010
|
|
2L5D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2l5d by Molmil](/molmil-images/mine/2l5d) | Solution Structures of human PIWI-like 1 PAZ domain with ssRNA (5'-pUGACA) | Descriptor: | 5'-R(*UP*GP*AP*CP*A)-3', Piwi-like protein 1 | Authors: | Zeng, L, Zhang, Q, Yan, K, Zhou, M. | Deposit date: | 2010-10-29 | Release date: | 2011-04-20 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural insights into piRNA recognition by the human PIWI-like 1 PAZ domain. Proteins, 79, 2011
|
|
2QUK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2quk by Molmil](/molmil-images/mine/2quk) | |