NMR Solution structure of the first PHD finger domain of human Autoimmune Regulator (AIRE) in complex with Histone H3(1-20Cys) Peptide

Summary for 2KFT

DescriptorAutoimmune regulator, Histone H3, ZINC ION (3 entities in total)
Functional Keywordsphd finger, histone code, aire, apeced, transcription, alternative splicing, cytoplasm, disease mutation, dna-binding, metal-binding, nucleus, phosphoprotein, polymorphism, transcription regulation, zinc, zinc-finger, chromosomal protein, nucleosome core, transcription-protein binding complex, transcription/protein binding
Biological sourceHomo sapiens (human)
Cellular locationNucleus O43918
Total number of polymer chains2
Total molecular weight8444.36
Chakravarty, S.,Zeng, L.,Zhou, M. (deposition date: 2009-02-27, release date: 2009-04-28, Last modification date: 2011-07-13)
Primary citation
Chakravarty, S.,Zeng, L.,Zhou, M.M.
Structure and Site-Specific Recognition of Histone H3 by the PHD Finger of Human Autoimmune Regulator.
Structure, 17:670-679, 2009
PubMed: 19446523 (PDB entries with the same primary citation)
DOI: 10.1016/j.str.2009.02.017
MImport into Mendeley
Experimental method
NMR Information

Structure validation

ClashscoreRamachandran outliersSidechain outliers316.2%9.3%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
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