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2KFT

NMR Solution structure of the first PHD finger domain of human Autoimmune Regulator (AIRE) in complex with Histone H3(1-20Cys) Peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Autoimmune regulatorpolymer566019.81UniProt (O43918)
Pfam (PF00628)
Homo sapiens (human)Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein, APECED protein
2B
(B)
Histone H3polymer212293.71
3C, D
(A)
ZINC IONnon-polymer65.42Chemie (ZN)
Sequence modifications
A: 294 - 347 (UniProt: O43918)
PDBExternal DatabaseDetails
Gly -2-expression tag
Ser -1-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight8313.5
Non-Polymers*Number of molecules2
Total formula weight130.8
All*Total formula weight8444.4
*Water molecules are not included.

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PDB entries from 2025-06-18

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