7WPQ
| Cryo-EM structure of VWF D'D3 dimer complexed with D1D2 at 3.27 angstron resolution (2 units) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, von Willebrand antigen 2, ... | Authors: | Zeng, J.W, Shu, Z.M, Zhou, A.W. | Deposit date: | 2022-01-24 | Release date: | 2022-05-25 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (3.267 Å) | Cite: | Structural basis of von Willebrand factor multimerization and tubular storage. Blood, 139, 2022
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7WPP
| Cryo-EM structure of VWF D'D3 dimer complexed with D1D2 at 2.85 angstron resolution (1 unit) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, von Willebrand antigen 2, ... | Authors: | Zeng, J.W, Shu, Z.M, Zhou, A.W. | Deposit date: | 2022-01-24 | Release date: | 2022-05-25 | Last modified: | 2022-06-15 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | Structural basis of von Willebrand factor multimerization and tubular storage. Blood, 139, 2022
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7WQT
| Cryo-EM structure of VWF D'D3 dimer complexed with D1D2 at 4.3 angstron resolution (VWF tube) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, von Willebrand antigen 2, ... | Authors: | Zeng, J.W, Shu, Z.M, Zhou, A.W. | Deposit date: | 2022-01-26 | Release date: | 2022-05-25 | Last modified: | 2024-10-30 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structural basis of von Willebrand factor multimerization and tubular storage. Blood, 139, 2022
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7WPS
| Cryo-EM structure of VWF D'D3 dimer complexed with D1D2 at 4.3 angstron resolution (7 units) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, von Willebrand antigen 2, ... | Authors: | Zeng, J.W, Shu, Z.M, Zhou, A.W. | Deposit date: | 2022-01-24 | Release date: | 2022-05-25 | Last modified: | 2022-06-15 | Method: | ELECTRON MICROSCOPY (4.32 Å) | Cite: | Structural basis of von Willebrand factor multimerization and tubular storage. Blood, 139, 2022
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7WPR
| VWF D'D3 dimer complexed with D1D2 at 4.39 angstron resolution(VWF tube) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, von Willebrand antigen 2, ... | Authors: | Zeng, J.W, Shu, Z.M, Zhou, A.W. | Deposit date: | 2022-01-24 | Release date: | 2022-05-25 | Last modified: | 2022-06-15 | Method: | ELECTRON MICROSCOPY (4.39 Å) | Cite: | Structural basis of von Willebrand factor multimerization and tubular storage. Blood, 139, 2022
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1D5L
| CRYSTAL STRUCTURE OF CYANIDE-BOUND HUMAN MYELOPEROXIDASE ISOFORM C AT PH 5.5 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CALCIUM ION, ... | Authors: | Fiedler, T.J, Davey, C.A, Fenna, R.E. | Deposit date: | 1999-10-07 | Release date: | 2001-12-12 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Human myeloperoxidase: structure of a cyanide complex and its interaction with bromide and thiocyanate substrates at 1.9 A resolution. Biochemistry, 40, 2001
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1CXP
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6S53
| Crystal structure of TRIM21 RING domain in complex with an isopeptide-linked Ube2N~ubiquitin conjugate | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, E3 ubiquitin-protein ligase TRIM21, Polyubiquitin-C, ... | Authors: | Kiss, L, Boland, A, Neuhaus, D, James, L.C. | Deposit date: | 2019-06-30 | Release date: | 2019-09-11 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A tri-ionic anchor mechanism drives Ube2N-specific recruitment and K63-chain ubiquitination in TRIM ligases. Nat Commun, 10, 2019
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8XRP
| The Cryo-EM structure of IL-12, receptor subunit beta-1 and receptor subunit beta-2 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 receptor subunit beta-1, Interleukin-12 receptor subunit beta-2, ... | Authors: | Chen, H.Q, Wang, X.Q, Ge, X.F, Zeng, J.W, Wang, J.W. | Deposit date: | 2024-01-07 | Release date: | 2024-07-24 | Last modified: | 2024-11-06 | Method: | ELECTRON MICROSCOPY (3.75 Å) | Cite: | Structure and assembly of the human IL-12 signaling complex. Structure, 32, 2024
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5GSA
| EED in complex with an allosteric PRC2 inhibitor | Descriptor: | Histone-lysine N-methyltransferase EZH2, N-(furan-2-ylmethyl)-8-(4-methylsulfonylphenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine, Polycomb protein EED | Authors: | Zhao, K, Zhao, M, Luo, X, Zhang, H. | Deposit date: | 2016-08-15 | Release date: | 2017-02-01 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of Nat. Chem. Biol., 13, 2017
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1D7W
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6K1H
| Structure of membrane protein | Descriptor: | PTS mannose transporter subunit IID, PTS system mannose-specific EIIC component, alpha-D-mannopyranose | Authors: | Wang, J.W, Zeng, J.W. | Deposit date: | 2019-05-10 | Release date: | 2019-07-10 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.52 Å) | Cite: | Structure of the mannose transporter of the bacterial phosphotransferase system. Cell Res., 29, 2019
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7VLY
| Cryo-EM structure of Listeria monocytogenes man-PTS complexed with pediocin PA-1 | Descriptor: | Bacteriocin pediocin PA-1, Mannose/fructose/sorbose family PTS transporter subunit IIC, PTS mannose family transporter subunit IID, ... | Authors: | Wang, J.W. | Deposit date: | 2021-10-05 | Release date: | 2021-12-01 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (2.45 Å) | Cite: | Structural Basis of Pore Formation in the Mannose Phosphotransferase System by Pediocin PA-1. Appl.Environ.Microbiol., 88, 2022
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7VLX
| Cryo-EM structures of Listeria monocytogenes man-PTS | Descriptor: | Mannose/fructose/sorbose family PTS transporter subunit IIC, PTS mannose family transporter subunit IID, alpha-D-mannopyranose | Authors: | Wang, J.W. | Deposit date: | 2021-10-05 | Release date: | 2021-12-01 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.12 Å) | Cite: | Structural Basis of Pore Formation in the Mannose Phosphotransferase System by Pediocin PA-1. Appl.Environ.Microbiol., 88, 2022
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7VI9
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7VII
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7VIA
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7VIK
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7ML7
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1D2V
| CRYSTAL STRUCTURE OF BROMIDE-BOUND HUMAN MYELOPEROXIDASE ISOFORM C AT PH 5.5 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, BROMIDE ION, ... | Authors: | Fiedler, T.J, Davey, C.A, Fenna, R.E. | Deposit date: | 1999-09-28 | Release date: | 2000-04-24 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | X-ray crystal structure and characterization of halide-binding sites of human myeloperoxidase at 1.8 A resolution. J.Biol.Chem., 275, 2000
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7QK4
| EED in complex with PRC2 allosteric inhibitor compound 22 (MAK683) | Descriptor: | CHLORIDE ION, Histone-lysine N-methyltransferase EZH2, N-[(5-fluoranyl-2,3-dihydro-1-benzofuran-4-yl)methyl]-8-(2-methylpyridin-3-yl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine, ... | Authors: | Zhao, K, Zhao, M, Luo, X, Zhang, H, Scheufler, C. | Deposit date: | 2021-12-17 | Release date: | 2022-04-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.602 Å) | Cite: | Discovery of the Clinical Candidate MAK683: An EED-Directed, Allosteric, and Selective PRC2 Inhibitor for the Treatment of Advanced Malignancies. J.Med.Chem., 65, 2022
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7QJU
| EED in complex with PRC2 allosteric inhibitor compound 7 | Descriptor: | CHLORIDE ION, Histone-lysine N-methyltransferase EZH2, N-(2,3-dihydro-1-benzofuran-4-ylmethyl)-8-[4-[(dimethylamino)methyl]phenyl]-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine, ... | Authors: | Zhao, K, Zhao, M, Luo, X, Zhang, H, Scheufler, C. | Deposit date: | 2021-12-17 | Release date: | 2022-04-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Discovery of the Clinical Candidate MAK683: An EED-Directed, Allosteric, and Selective PRC2 Inhibitor for the Treatment of Advanced Malignancies. J.Med.Chem., 65, 2022
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7QJG
| EED in complex with PRC2 allosteric inhibitor compound 6 | Descriptor: | CHLORIDE ION, Histone-lysine N-methyltransferase EZH2, N-(2,3-dihydro-1-benzofuran-7-ylmethyl)-8-[4-[(dimethylamino)methyl]phenyl]-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine, ... | Authors: | Zhao, K, Zhao, M, Luo, X, Zhang, H, Scheufler, C. | Deposit date: | 2021-12-16 | Release date: | 2022-04-13 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Discovery of the Clinical Candidate MAK683: An EED-Directed, Allosteric, and Selective PRC2 Inhibitor for the Treatment of Advanced Malignancies. J.Med.Chem., 65, 2022
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8JVM
| AHS-CSF domains of phage lambda tail | Descriptor: | Tip attachment protein J | Authors: | Wang, J. | Deposit date: | 2023-06-28 | Release date: | 2023-10-18 | Last modified: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (3.86 Å) | Cite: | Architecture of the bacteriophage lambda tail. Structure, 32, 2024
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8KGE
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