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8C06
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BU of 8c06 by Molmil
Structure of Dimeric HECT E3 Ubiquitin Ligase UBR5
Descriptor: E3 ubiquitin-protein ligase UBR5, ZINC ION
Authors:Hehl, L.A, Prabu, J.R, Schulman, B.A.
Deposit date:2022-12-16
Release date:2023-08-23
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural snapshots along K48-linked ubiquitin chain formation by the HECT E3 UBR5.
Nat.Chem.Biol., 20, 2024
4PPG
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BU of 4ppg by Molmil
Mycobacterium tuberculosis RecA citrate bound low temperature structure IIA-BR
Descriptor: CITRATE ANION, Protein RecA, 1st part, ...
Authors:Chandran, A.V, Prabu, J.R, Patil, N.K, Muniyappa, K, Vijayan, M.
Deposit date:2014-02-27
Release date:2015-03-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural studies on Mycobacterium tuberculosis RecA: Molecular plasticity and interspecies variability
J.Biosci., 40, 2015
4PPQ
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BU of 4ppq by Molmil
Mycobacterium tuberculosis RecA citrate bound low temperature structure IIA-CR
Descriptor: 1,2-ETHANEDIOL, CITRATE ANION, Protein RecA, ...
Authors:Chandran, A.V, Prabu, J.R, Patil, N.K, Muniyappa, K, Vijayan, M.
Deposit date:2014-02-27
Release date:2015-03-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural studies on Mycobacterium tuberculosis RecA: Molecular plasticity and interspecies variability
J.Biosci., 40, 2015
4PQY
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BU of 4pqy by Molmil
Mycobacterium tuberculosis RecA glycerol bound low temperature structure IIC-N4
Descriptor: GLYCEROL, Protein RecA, 1st part, ...
Authors:Chandran, A.V, Prabu, J.R, Patil, N.K, Muniyappa, K, Vijayan, M.
Deposit date:2014-03-05
Release date:2015-03-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural studies on Mycobacterium tuberculosis RecA: Molecular plasticity and interspecies variability
J.Biosci., 40, 2015
4PO8
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BU of 4po8 by Molmil
Mycobacterium tuberculosis RecA glycerol bound low temperature structure IIC-CR
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Protein RecA, ...
Authors:Chandran, A.V, Prabu, J.R, Patil, N.K, Muniyappa, K, Vijayan, M.
Deposit date:2014-02-25
Release date:2015-03-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural studies on Mycobacterium tuberculosis RecA: Molecular plasticity and interspecies variability
J.Biosci., 40, 2015
4PQF
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BU of 4pqf by Molmil
Mycobacterium tuberculosis RecA glycerol bound low temperature structure IIB-CR
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Protein RecA, ...
Authors:Chandran, A.V, Prabu, J.R, Patil, N.K, Muniyappa, K, Vijayan, M.
Deposit date:2014-03-03
Release date:2015-03-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural studies on Mycobacterium tuberculosis RecA: Molecular plasticity and interspecies variability
J.Biosci., 40, 2015
4PQR
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BU of 4pqr by Molmil
Mycobacterium tuberculosis RecA glycerol bound low temperature structure IIB-BN
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Protein RecA, ...
Authors:Chandran, A.V, Prabu, J.R, Patil, N.K, Muniyappa, K, Vijayan, M.
Deposit date:2014-03-04
Release date:2015-03-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural studies on Mycobacterium tuberculosis RecA: Molecular plasticity and interspecies variability
J.Biosci., 40, 2015
4PR0
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BU of 4pr0 by Molmil
Mycobacterium tuberculosis RecA glycerol bound low temperature structure IIC-N3
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Protein RecA, ...
Authors:Chandran, A.V, Prabu, J.R, Patil, N.K, Muniyappa, K, Vijayan, M.
Deposit date:2014-03-05
Release date:2015-03-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural studies on Mycobacterium tuberculosis RecA: Molecular plasticity and interspecies variability
J.Biosci., 40, 2015
4PSA
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BU of 4psa by Molmil
Mycobacterium tuberculosis RecA glycerol bound low temperature structure IIC-N1
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Protein RecA, ...
Authors:Chandran, A.V, Prabu, J.R, Patil, N.K, Muniyappa, K, Vijayan, M.
Deposit date:2014-03-07
Release date:2015-03-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural studies on Mycobacterium tuberculosis RecA: Molecular plasticity and interspecies variability
J.Biosci., 40, 2015
4PSK
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BU of 4psk by Molmil
Mycobacterium tuberculosis RecA phosphate bound low temperature structure I-LT
Descriptor: PHOSPHATE ION, Protein RecA, 1st part, ...
Authors:Chandran, A.V, Prabu, J.R, Patil, N.K, Muniyappa, K, Vijayan, M.
Deposit date:2014-03-07
Release date:2015-03-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural studies on Mycobacterium tuberculosis RecA: Molecular plasticity and interspecies variability
J.Biosci., 40, 2015
4PPN
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BU of 4ppn by Molmil
Mycobacterium tuberculosis RecA citrate bound low temperature structure IIA-BN
Descriptor: 1,2-ETHANEDIOL, CITRATE ANION, Protein RecA, ...
Authors:Chandran, A.V, Prabu, J.R, Patil, N.K, Muniyappa, K, Vijayan, M.
Deposit date:2014-02-27
Release date:2015-03-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural studies on Mycobacterium tuberculosis RecA: Molecular plasticity and interspecies variability
J.Biosci., 40, 2015
4PO9
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BU of 4po9 by Molmil
Mycobacterium tuberculosis RecA glycerol bound low temperature structure IIC-BR
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Protein RecA, ...
Authors:Chandran, A.V, Prabu, J.R, Patil, N.K, Muniyappa, K, Vijayan, M.
Deposit date:2014-02-25
Release date:2015-03-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural studies on Mycobacterium tuberculosis RecA: Molecular plasticity and interspecies variability
J.Biosci., 40, 2015
4PSV
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BU of 4psv by Molmil
Mycobacterium tuberculosis RecA phosphate bound room temperature structure I-RT
Descriptor: PHOSPHATE ION, Protein RecA, 1st part, ...
Authors:Chandran, A.V, Prabu, J.R, Patil, N.K, Muniyappa, K, Vijayan, M.
Deposit date:2014-03-08
Release date:2015-03-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural studies on Mycobacterium tuberculosis RecA: Molecular plasticity and interspecies variability
J.Biosci., 40, 2015
4PO1
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BU of 4po1 by Molmil
Mycobacterium tuberculosis RecA glycerol bound room temperature structure IIC-RT
Descriptor: GLYCEROL, Protein RecA
Authors:Chandran, A.V, Prabu, J.R, Patil, N.K, Muniyappa, K, Vijayan, M.
Deposit date:2014-02-23
Release date:2015-03-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural studies on Mycobacterium tuberculosis RecA: Molecular plasticity and interspecies variability
J.Biosci., 40, 2015
4POA
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BU of 4poa by Molmil
Mycobacterium tuberculosis RecA glycerol bound low temperature structure IIC-BN
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Protein RecA, ...
Authors:Chandran, A.V, Prabu, J.R, Patil, N.K, Muniyappa, K, Vijayan, M.
Deposit date:2014-02-25
Release date:2015-03-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural studies on Mycobacterium tuberculosis RecA: Molecular plasticity and interspecies variability
J.Biosci., 40, 2015
4PPF
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BU of 4ppf by Molmil
Mycobacterium tuberculosis RecA citrate bound low temperature structure IIA-N
Descriptor: 1,2-ETHANEDIOL, CITRATE ANION, Protein RecA, ...
Authors:Chandran, A.V, Prabu, J.R, Patil, N.K, Muniyappa, K, Vijayan, M.
Deposit date:2014-02-26
Release date:2015-03-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural studies on Mycobacterium tuberculosis RecA: Molecular plasticity and interspecies variability
J.Biosci., 40, 2015
7ADO
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BU of 7ado by Molmil
Cryo-EM structure of human ER membrane protein complex in lipid nanodiscs
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ER membrane protein complex subunit 1, ...
Authors:Braeuning, B, Prabu, J.R, Miller-Vedam, L.E, Weissman, J.S, Frost, A, Schulman, B.A.
Deposit date:2020-09-15
Release date:2020-12-02
Last modified:2021-01-20
Method:ELECTRON MICROSCOPY (3.39 Å)
Cite:Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients.
Elife, 9, 2020
7ADP
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BU of 7adp by Molmil
Cryo-EM structure of human ER membrane protein complex in GDN detergent
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ER membrane protein complex subunit 1, ER membrane protein complex subunit 10, ...
Authors:Braeuning, B, Prabu, J.R, Miller-Vedam, L.E, Weissman, J.S, Frost, A, Schulman, B.A.
Deposit date:2020-09-15
Release date:2020-12-02
Last modified:2020-12-09
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients.
Elife, 9, 2020
8OIF
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BU of 8oif by Molmil
Structure of the UBE1L activating enzyme bound to ISG15 and UBE2L6
Descriptor: ADENOSINE MONOPHOSPHATE, Ubiquitin-like modifier-activating enzyme 7, Ubiquitin-like protein ISG15, ...
Authors:Wallace, I, Kheewoong, B, Prabu, J.R, Vollrath, R, von Gronau, S, Schulman, B.A, Swatek, K.N.
Deposit date:2023-03-22
Release date:2023-12-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Insights into the ISG15 transfer cascade by the UBE1L activating enzyme.
Nat Commun, 14, 2023
8Q7R
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BU of 8q7r by Molmil
Ubiquitin ligation to substrate by a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-FEM1C with trapped UBE2R2~donor UB-Sil1 peptide
Descriptor: 5-azanyl-1-oxidanyl-pentan-2-one, Cullin-2, E3 ubiquitin-protein ligase RBX1, ...
Authors:Liwocha, J, Prabu, J.R, Kleiger, G, Schulman, B.A.
Deposit date:2023-08-16
Release date:2024-02-21
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.71 Å)
Cite:Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting.
Mol.Cell, 84, 2024
7B5N
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BU of 7b5n by Molmil
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-UBE2L3~Ub~ARIH1.
Descriptor: 5-azanylpentan-2-one, Cullin-1, E3 ubiquitin-protein ligase ARIH1, ...
Authors:Horn-Ghetko, D, Prabu, J.R, Schulman, B.A.
Deposit date:2020-12-05
Release date:2021-02-10
Last modified:2021-03-10
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly.
Nature, 590, 2021
7B5R
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BU of 7b5r by Molmil
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-SKP1-SKP2-CKSHS1-Cyclin A-CDK2-p27
Descriptor: Cullin-1, Cyclin-A2, Cyclin-dependent kinase 2, ...
Authors:Horn-Ghetko, D, Prabu, J.R, Schulman, B.A.
Deposit date:2020-12-07
Release date:2021-02-10
Last modified:2021-03-10
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly.
Nature, 590, 2021
7B5S
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BU of 7b5s by Molmil
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-ARIH1 Ariadne. Transition State 1
Descriptor: Cullin-1, E3 ubiquitin-protein ligase ARIH1, E3 ubiquitin-protein ligase RBX1, ...
Authors:Horn-Ghetko, D, Prabu, J.R, Schulman, B.A.
Deposit date:2020-12-07
Release date:2021-02-10
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly.
Nature, 590, 2021
7B5L
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BU of 7b5l by Molmil
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-SKP1-SKP2-CKSHS1-Cyclin A-CDK2-p27-UBE2L3~Ub~ARIH1. Transition State 1
Descriptor: 5-azanylpentan-2-one, Cullin-1, Cyclin-A2, ...
Authors:Horn-Ghetko, D, Prabu, J.R, Schulman, B.A.
Deposit date:2020-12-04
Release date:2021-02-10
Last modified:2021-03-10
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly.
Nature, 590, 2021
7B5M
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BU of 7b5m by Molmil
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-SKP1-SKP2-CKSHS1-p27~Ub~ARIH1. Transition State 2
Descriptor: Cullin-1, Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinases regulatory subunit 1, ...
Authors:Horn-Ghetko, D, Prabu, J.R, Schulman, B.A.
Deposit date:2020-12-05
Release date:2021-02-17
Last modified:2021-03-10
Method:ELECTRON MICROSCOPY (3.91 Å)
Cite:Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly.
Nature, 590, 2021

222624

數據於2024-07-17公開中

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