7ADP

Cryo-EM structure of human ER membrane protein complex in GDN detergent

Summary for 7ADP

• Entry DOI: 10.2210/pdb7adp/pdb
• Related: 7ADO
• EMDB information: 11732 11733
• Descriptor: ER membrane protein complex subunit 1, ER membrane protein complex subunit 2, ER membrane protein complex subunit 3, ... (9 entities in total)
• Functional Keywords: er membrane protein, emc, membrane protein biogenesis, membrane protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 276505.75

Authors

Braeuning, B.,Prabu, J.R.,Miller-Vedam, L.E.,Weissman, J.S.,Frost, A.,Schulman, B.A. (deposition date: 2020-09-15, release date: 2020-12-02, Last modification date: 2020-12-09)

• Primary citation: Miller-Vedam, L.E.,Brauning, B.,Popova, K.D.,Schirle Oakdale, N.T.,Bonnar, J.L.,Prabu, J.R.,Boydston, E.A.,Sevillano, N.,Shurtleff, M.J.,Stroud, R.M.,Craik, C.S.,Schulman, B.A.,Frost, A.,Weissman, J.S.; Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients.; Elife, 9:-, 2020; PubMed: 33236988; DOI: 10.7554/eLife.62611

Experimental method

ELECTRON MICROSCOPY (3.6 Å)