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4UYU
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BU of 4uyu by Molmil
STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM I IODIDE COMPLEX - 2.3A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, IODIDE ION, ...
Authors:Zebisch, M, Jones, E.Y.
Deposit date:2014-09-03
Release date:2015-02-25
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Notum Deacylates Wnt Proteins to Suppress Signalling Activity.
Nature, 519, 2015
4UZQ
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BU of 4uzq by Molmil
STRUCTURE OF THE WNT DEACYLASE NOTUM IN COMPLEX WITH O-PALMITOLEOYL SERINE - CRYSTAL FORM IX - 1.5A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, PALMITOLEIC ACID, ...
Authors:Zebisch, M, Jones, E.Y.
Deposit date:2014-09-07
Release date:2015-02-25
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Notum Deacylates Wnt Proteins to Suppress Signalling Activity.
Nature, 519, 2015
4UZJ
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BU of 4uzj by Molmil
STRUCTURE OF THE WNT DEACYLASE NOTUM FROM DROSOPHILA - CRYSTAL FORM I - 2.4A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, NOTUM
Authors:Zebisch, M, Jones, E.Y.
Deposit date:2014-09-05
Release date:2015-02-25
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Notum Deacylates Wnt Proteins to Suppress Signalling Activity.
Nature, 519, 2015
4UZK
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BU of 4uzk by Molmil
STRUCTURE OF THE WNT DEACYLASE NOTUM FROM DROSOPHILA - CRYSTAL FORM II - 1.9A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, NOTUM
Authors:Zebisch, M, Jones, E.Y.
Deposit date:2014-09-05
Release date:2015-02-25
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Notum Deacylates Wnt Proteins to Suppress Signalling Activity.
Nature, 519, 2015
4UZL
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BU of 4uzl by Molmil
STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM I MYRISTOLEATE COMPLEX - 2.1A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Myristoleic acid, PROTEIN NOTUM HOMOLOG
Authors:Zebisch, M, Jones, E.Y.
Deposit date:2014-09-05
Release date:2015-02-25
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Notum Deacylates Wnt Proteins to Suppress Signalling Activity.
Nature, 519, 2015
4UU6
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BU of 4uu6 by Molmil
CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF PALS1
Descriptor: ACETATE ION, CHLORIDE ION, GLYCEROL, ...
Authors:Ivanova, M.E, Purkiss, A.G, McDonald, N.Q.
Deposit date:2014-07-24
Release date:2015-01-14
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of the human Pals1 PDZ domain with and without ligand suggest gated access of Crb to the PDZ peptide-binding groove.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
4UZA
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BU of 4uza by Molmil
STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM VIII - PHOSPHATE COMPLEX - 2.4A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATE ION, PROTEIN NOTUM HOMOLOG
Authors:Zebisch, M, Jones, E.Y.
Deposit date:2014-09-04
Release date:2015-02-25
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Notum Deacylates Wnt Proteins to Suppress Signalling Activity.
Nature, 519, 2015
4UZ7
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BU of 4uz7 by Molmil
STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM VI - 2.2A
Descriptor: CHLORIDE ION, PROTEIN NOTUM HOMOLOG
Authors:Zebisch, M, Jones, E.Y.
Deposit date:2014-09-04
Release date:2015-02-25
Last modified:2015-03-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Notum Deacylates Wnt Proteins to Suppress Signalling Activity.
Nature, 519, 2015
4UZ5
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BU of 4uz5 by Molmil
STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM IV - 2.1A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, NOTUM
Authors:Zebisch, M, Jones, E.Y.
Deposit date:2014-09-04
Release date:2015-02-25
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Notum Deacylates Wnt Proteins to Suppress Signalling Activity.
Nature, 519, 2015
2W10
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BU of 2w10 by Molmil
Mona SH3C in complex
Descriptor: GRB2-RELATED ADAPTOR PROTEIN 2, PHOSPHATE ION, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 23
Authors:Harkiolaki, M, Feller, S.M.
Deposit date:2008-10-13
Release date:2009-05-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Distinct Binding Modes of Two Epitopes in Gab2 that Interact with the Sh3C Domain of Grb2.
Structure, 17, 2009
6XTZ
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BU of 6xtz by Molmil
Structure of Dally-like protein in complex with O-palmitoleoyl serine
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Dally-like, ...
Authors:Vecchia, L, Jones, E.Y.
Deposit date:2020-01-16
Release date:2020-07-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Glypicans shield the Wnt lipid moiety to enable signalling at a distance.
Nature, 585, 2020
6YUF
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BU of 6yuf by Molmil
Cohesin complex with loader gripping DNA
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Cohesin subunit rad21, ...
Authors:Higashi, T.L, Eickhoff, P, Sousa, J.S, Costa, A, Uhlmann, F.
Deposit date:2020-04-27
Release date:2020-08-19
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.94 Å)
Cite:A Structure-Based Mechanism for DNA Entry into the Cohesin Ring.
Mol.Cell, 79, 2020
4UU5
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BU of 4uu5 by Molmil
CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF PALS1 IN COMPLEX WITH THE CRB PEPTIDE
Descriptor: 2,2,4,4,6,6,8-heptamethylnonane, CHLORIDE ION, MAGUK P55 SUBFAMILY MEMBER 5, ...
Authors:Ivanova, M.E, Purkiss, A.G, McDonald, N.Q.
Deposit date:2014-07-24
Release date:2015-01-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.23 Å)
Cite:Structures of the human Pals1 PDZ domain with and without ligand suggest gated access of Crb to the PDZ peptide-binding groove.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
4WBH
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BU of 4wbh by Molmil
STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM I APO - 2.2A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Protein notum homolog, ...
Authors:Zebisch, M, Jones, E.Y.
Deposit date:2014-09-03
Release date:2015-02-25
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Notum deacylates Wnt proteins to suppress signalling activity
Nature, 519, 2015
4WCI
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BU of 4wci by Molmil
Crystal structure of the 1st SH3 domain from human CD2AP (CMS) in complex with a proline-rich peptide (aa 378-393) from human RIN3
Descriptor: CD2-associated protein, Ras and Rab interactor 3, SULFATE ION
Authors:Rouka, E, Simister, P.C, Janning, M, Kirsch, K.H, Krojer, T, Knapp, S, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Feller, S.M, Structural Genomics Consortium (SGC)
Deposit date:2014-09-04
Release date:2015-08-19
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Differential Recognition Preferences of the Three Src Homology 3 (SH3) Domains from the Adaptor CD2-associated Protein (CD2AP) and Direct Association with Ras and Rab Interactor 3 (RIN3).
J.Biol.Chem., 290, 2015
6YA6
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BU of 6ya6 by Molmil
Minimal construct of Cdc7-Dbf4 bound to XL413
Descriptor: 8-chloro-2-[(2S)-pyrrolidin-2-yl][1]benzofuro[3,2-d]pyrimidin-4(3H)-one, BORIC ACID, CHLORIDE ION, ...
Authors:Dick, S.D, Cherepanov, P.
Deposit date:2020-03-11
Release date:2020-05-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Structural Basis for the Activation and Target Site Specificity of CDC7 Kinase.
Structure, 28, 2020
6YA8
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BU of 6ya8 by Molmil
Cdc7-Dbf4 bound to ADP-BeF3
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Cell division cycle 7-related protein kinase,Cell division cycle 7-related protein kinase,Cell division cycle 7-related protein kinase, ...
Authors:Dick, S.D, Cherepanov, P.
Deposit date:2020-03-11
Release date:2020-05-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Structural Basis for the Activation and Target Site Specificity of CDC7 Kinase.
Structure, 28, 2020
6YA7
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BU of 6ya7 by Molmil
Cdc7-Dbf4 bound to an Mcm2-S40 derived bivalent substrate
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cell division cycle 7-related protein kinase,Cell division cycle 7-related protein kinase,Cell division cycle 7-related protein kinase, DNA replication licensing factor MCM2, ...
Authors:Dick, S.D, Cherepanov, P.
Deposit date:2020-03-11
Release date:2020-05-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Structural Basis for the Activation and Target Site Specificity of CDC7 Kinase.
Structure, 28, 2020
6ZEJ
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BU of 6zej by Molmil
Structure of PP1-Phactr1 chimera [PP1(7-304) + linker (SGSGS) + Phactr1(526-580)]
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, MANGANESE (II) ION, ...
Authors:Mouilleron, S, Treisman, R, Fedoryshchak, R, Lee, R, Butler, A.M, Prechova, M.
Deposit date:2020-06-16
Release date:2020-09-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Molecular basis for substrate specificity of the Phactr1/PP1 phosphatase holoenzyme.
Elife, 9, 2020
5MLU
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BU of 5mlu by Molmil
Crystal structure of the PFV GAG CBS bound to a mononucleosome
Descriptor: DNA (145-MER), Histone H2A type 1, Histone H2B, ...
Authors:Pye, V.E, Maskell, D.P, Lesbats, P, Cherepanov, P.
Deposit date:2016-12-07
Release date:2017-05-10
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for spumavirus GAG tethering to chromatin.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5LIH
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BU of 5lih by Molmil
Structure of a peptide-substrate bound to PKCiota core kinase domain
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MANGANESE (II) ION, ...
Authors:Soriano, E.V, Purkiss, A.G, McDonald, N.Q.
Deposit date:2016-07-14
Release date:2016-09-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:aPKC Inhibition by Par3 CR3 Flanking Regions Controls Substrate Access and Underpins Apical-Junctional Polarization.
Dev.Cell, 38, 2016
5LI9
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BU of 5li9 by Molmil
Structure of a nucleotide-bound form of PKCiota core kinase domain
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Ivanova, M.E, Purkiss, A.G, McDonald, N.Q.
Deposit date:2016-07-14
Release date:2016-09-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:aPKC Inhibition by Par3 CR3 Flanking Regions Controls Substrate Access and Underpins Apical-Junctional Polarization.
Dev.Cell, 38, 2016
5LXH
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BU of 5lxh by Molmil
GABARAP-L1 ATG4B LIR Complex
Descriptor: Cysteine protease ATG4B, GLYCEROL, Gamma-aminobutyric acid receptor-associated protein-like 1, ...
Authors:Mouilleron, S, Skytte Rasmussen, M, Kumar Shrestha, B, Wirth, M, Bowitz Larsen, K, Abudu Princely, Y, Sjottem, E, Tooze, S, Lamark, T, Johansen, T, Lee, R.
Deposit date:2016-09-21
Release date:2017-02-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:ATG4B contains a C-terminal LIR motif important for binding and efficient cleavage of mammalian orthologs of yeast Atg8.
Autophagy, 13, 2017
5LXI
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BU of 5lxi by Molmil
GABARAP-L1 ATG4B LIR Complex
Descriptor: 1,2-ETHANEDIOL, Cysteine protease ATG4B, DI(HYDROXYETHYL)ETHER, ...
Authors:Mouilleron, S, Skytte Rasmussen, M, Kumar Shrestha, B, Wirth, M, Bowitz Larsen, K, Abudu Princely, Y, Sjottem, E, Tooze, S, Lamark, T, Johansen, T, Lee, R.
Deposit date:2016-09-21
Release date:2017-02-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:ATG4B contains a C-terminal LIR motif important for binding and efficient cleavage of mammalian orthologs of yeast Atg8.
Autophagy, 13, 2017
6ZEI
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BU of 6zei by Molmil
Structure of PP1-IRSp53 S455E chimera [PP1(7-304) + linker (G/S)x9 + IRSp53(449-465)] bound to Phactr1 (516-580)
Descriptor: GLYCEROL, MANGANESE (II) ION, PHOSPHATE ION, ...
Authors:Mouilleron, S, Treisman, R, Fedoryshchak, R, Lee, R, Butler, A.M, Prechova, M.
Deposit date:2020-06-16
Release date:2020-09-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Molecular basis for substrate specificity of the Phactr1/PP1 phosphatase holoenzyme.
Elife, 9, 2020

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數據於2024-07-24公開中

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