4WCI
Crystal structure of the 1st SH3 domain from human CD2AP (CMS) in complex with a proline-rich peptide (aa 378-393) from human RIN3
Summary for 4WCI
Entry DOI | 10.2210/pdb4wci/pdb |
Related | 3U23 |
Descriptor | CD2-associated protein, Ras and Rab interactor 3, SULFATE ION, ... (4 entities in total) |
Functional Keywords | endocytosis adaptor protein protein-peptide binary complex kidney, signaling protein, structural genomics, structural genomics consortium, sgc |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm, cytoskeleton : Q9Y5K6 Cytoplasm : Q8TB24 |
Total number of polymer chains | 6 |
Total formula weight | 28448.12 |
Authors | Rouka, E.,Simister, P.C.,Janning, M.,Kirsch, K.H.,Krojer, T.,Knapp, S.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Feller, S.M.,Structural Genomics Consortium (SGC) (deposition date: 2014-09-04, release date: 2015-08-19, Last modification date: 2024-01-10) |
Primary citation | Rouka, E.,Simister, P.C.,Janning, M.,Kumbrink, J.,Konstantinou, T.,Muniz, J.R.,Joshi, D.,O'Reilly, N.,Volkmer, R.,Ritter, B.,Knapp, S.,von Delft, F.,Kirsch, K.H.,Feller, S.M. Differential Recognition Preferences of the Three Src Homology 3 (SH3) Domains from the Adaptor CD2-associated Protein (CD2AP) and Direct Association with Ras and Rab Interactor 3 (RIN3). J.Biol.Chem., 290:25275-25292, 2015 Cited by PubMed: 26296892DOI: 10.1074/jbc.M115.637207 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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