3U23
Atomic resolution crystal structure of the 2nd SH3 domain from human CD2AP (CMS) in complex with a proline-rich peptide from human RIN3
Summary for 3U23
Entry DOI | 10.2210/pdb3u23/pdb |
Related | 2FEI 2KRN 4WCI |
Descriptor | CD2-associated protein, Ras and Rab interactor 3, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | structural genomics, structural genomics consortium, sgc, beta-barrel, adaptor protein, protein binding |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm, cytoskeleton : Q9Y5K6 Cytoplasm : Q8TB24 |
Total number of polymer chains | 2 |
Total formula weight | 9309.63 |
Authors | Simister, P.C.,Rouka, E.,Janning, M.,Muniz, J.R.C.,Kirsch, K.H.,Knapp, S.,von Delft, F.,Filippakopoulos, P.,Arrowsmith, C.H.,Krojer, T.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Feller, S.M.,Structural Genomics Consortium (SGC) (deposition date: 2011-09-30, release date: 2011-12-28, Last modification date: 2023-09-13) |
Primary citation | Rouka, E.,Simister, P.C.,Janning, M.,Kumbrink, J.,Konstantinou, T.,Muniz, J.R.,Joshi, D.,O'Reilly, N.,Volkmer, R.,Ritter, B.,Knapp, S.,von Delft, F.,Kirsch, K.H.,Feller, S.M. Differential Recognition Preferences of the Three Src Homology 3 (SH3) Domains from the Adaptor CD2-associated Protein (CD2AP) and Direct Association with Ras and Rab Interactor 3 (RIN3). J.Biol.Chem., 290:25275-25292, 2015 Cited by PubMed: 26296892DOI: 10.1074/jbc.M115.637207 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.11 Å) |
Structure validation
Download full validation report