3U23
Atomic resolution crystal structure of the 2nd SH3 domain from human CD2AP (CMS) in complex with a proline-rich peptide from human RIN3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CD2-associated protein | polymer | 65 | 7444.4 | 1 | UniProt (Q9Y5K6) Pfam (PF14604) | Homo sapiens (human) | Adapter protein CMS, Cas ligand with multiple SH3 domains |
| 2 | B (B) | Ras and Rab interactor 3 | polymer | 17 | 1803.2 | 1 | UniProt (Q8TB24) | Homo sapiens | Ras interaction/interference protein 3 |
| 3 | C (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 86 | Chemie (HOH) |
Sequence modifications
A: 109 - 168 (UniProt: Q9Y5K6)
B: 452 - 467 (UniProt: Q8TB24)
| PDB | External Database | Details |
|---|---|---|
| Gly 104 | - | expression tag |
| Pro 105 | - | expression tag |
| Leu 106 | - | expression tag |
| Gly 107 | - | expression tag |
| Ser 108 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Nh2 468 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 9247.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 62.1 | |
| All* | Total formula weight | 9309.6 |
