6YUF

Cohesin complex with loader gripping DNA

Summary for 6YUF

Entry DOI	10.2210/pdb6yuf/pdb
EMDB information	10930
Descriptor	Cohesin subunit rad21, Sister chromatid cohesion protein mis4, Structural maintenance of chromosomes protein 1, ... (8 entities in total)
Functional Keywords	chromosome segregation sister chromatid cohesion smc complexes cohesin abc-atpase mis4-scc2-nipbl, dna binding protein
Biological source	Schizosaccharomyces pombe (strain 972 / ATCC 24843) More
Total number of polymer chains	6
Total formula weight	547283.87
Authors	Higashi, T.L.,Eickhoff, P.,Sousa, J.S.,Costa, A.,Uhlmann, F. (deposition date: 2020-04-27, release date: 2020-08-19, Last modification date: 2020-09-30)
Primary citation	Higashi, T.L.,Eickhoff, P.,Sousa, J.S.,Locke, J.,Nans, A.,Flynn, H.R.,Snijders, A.P.,Papageorgiou, G.,O'Reilly, N.,Chen, Z.A.,O'Reilly, F.J.,Rappsilber, J.,Costa, A.,Uhlmann, F. A Structure-Based Mechanism for DNA Entry into the Cohesin Ring. Mol.Cell, 79:917-, 2020 Cited by PubMed: 32755595 DOI: 10.1016/j.molcel.2020.07.013 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.94 Å)

Structure validation