5LI9

Structure of a nucleotide-bound form of PKCiota core kinase domain

Summary for 5LI9

• Entry DOI: 10.2210/pdb5li9/pdb
• Descriptor: Protein kinase C iota type, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, FORMIC ACID, ... (8 entities in total)
• Functional Keywords: apkc, polarity, complex, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 41931.65

Authors

Ivanova, M.E.,Purkiss, A.G.,McDonald, N.Q. (deposition date: 2016-07-14, release date: 2016-09-14, Last modification date: 2024-01-10)

• Primary citation: Soriano, E.V.,Ivanova, M.E.,Fletcher, G.,Riou, P.,Knowles, P.P.,Barnouin, K.,Purkiss, A.,Kostelecky, B.,Saiu, P.,Linch, M.,Elbediwy, A.,Kjr, S.,O'Reilly, N.,Snijders, A.P.,Parker, P.J.,Thompson, B.J.,McDonald, N.Q.; aPKC Inhibition by Par3 CR3 Flanking Regions Controls Substrate Access and Underpins Apical-Junctional Polarization.; Dev.Cell, 38:384-398, 2016; PubMed: 27554858; DOI: 10.1016/j.devcel.2016.07.018

Experimental method

X-RAY DIFFRACTION (1.79 Å)