5LI9
Structure of a nucleotide-bound form of PKCiota core kinase domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protein kinase C iota type | polymer | 350 | 40480.6 | 1 | UniProt (P41743) Pfam (PF00069) Pfam (PF00433) | Homo sapiens (Human) | Atypical protein kinase C-lambda/iota,aPKC-lambda/iota,nPKC-iota |
| 2 | B (A) | PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | non-polymer | 505.2 | 1 | Chemie (ACP) | |||
| 3 | C, D, E, F, G... (A) | FORMIC ACID | non-polymer | 46.0 | 7 | Chemie (FMT) | |||
| 4 | J (A) | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
| 5 | K (A) | (4R)-2-METHYLPENTANE-2,4-DIOL | non-polymer | 118.2 | 1 | Chemie (MRD) | |||
| 6 | L, M, N (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) | |||
| 7 | O, P (A) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 8 | Q (A) | water | water | 18.0 | 244 | Chemie (HOH) |
Sequence modifications
A: 248 - 596 (UniProt: P41743)
| PDB | External Database | Details |
|---|---|---|
| Phe 247 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40480.6 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 1451.1 | |
| All* | Total formula weight | 41931.6 |
