2QU5
| Crystal structure of the VEGFR2 kinase domain in complex with a benzimidazole inhibitor | Descriptor: | 4-[[2-[[4-chloro-3-(trifluoromethyl)phenyl]amino]-3H-benzimidazol-5-yl]oxy]-N-methyl-pyridine-2-carboxamide, Vascular endothelial growth factor receptor 2 | Authors: | Whittington, D.A, Kim, J.L, Long, A.M, Rose, P, Gu, Y, Zhao, H. | Deposit date: | 2007-08-03 | Release date: | 2007-09-25 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Design, Synthesis, and Evaluation of Orally Active Benzimidazoles and Benzoxazoles as Vascular Endothelial Growth Factor-2 Receptor Tyrosine Kinase Inhibitors. J.Med.Chem., 50, 2007
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7SQT
| Goslar chimallin cubic (O, 24mer) assembly | Descriptor: | Chimallin | Authors: | Laughlin, T.G, Deep, A, Prichard, A.M, Seitz, C, Gu, Y, Enustun, E, Suslov, S, Khanna, K, Birkholz, E.A, Amaro, R.E, Pogliano, J, Corbett, K.D, Villa, E. | Deposit date: | 2021-11-06 | Release date: | 2022-07-27 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Architecture and self-assembly of the jumbo bacteriophage nuclear shell. Nature, 608, 2022
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7SQQ
| 201Phi2-1 Chimallin Cubic (O, 24mer) assembly | Descriptor: | Chimallin | Authors: | Laughlin, T.G, Deep, A, Prichard, A.M, Seitz, C, Gu, Y, Enustun, E, Suslov, S, Khanna, K, Birkholz, E.A, Amaro, R.E, Pogliano, J, Corbett, K.D, Villa, E. | Deposit date: | 2021-11-06 | Release date: | 2022-07-27 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Architecture and self-assembly of the jumbo bacteriophage nuclear shell. Nature, 608, 2022
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7SQS
| 201phi2-1 Chimallin C1 localized reconstruction | Descriptor: | Chimallin | Authors: | Laughlin, T.G, Deep, A, Prichard, A.M, Seitz, C, Gu, Y, Enustun, E, Suslov, S, Khanna, K, Birkholz, E.A, Amaro, R.E, Pogliano, J, Corbett, K.D, Villa, E. | Deposit date: | 2021-11-06 | Release date: | 2022-07-27 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Architecture and self-assembly of the jumbo bacteriophage nuclear shell. Nature, 608, 2022
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7SQR
| 201phi2-1 Chimallin localized tetramer reconstruction | Descriptor: | Chimallin | Authors: | Laughlin, T.G, Deep, A, Prichard, A.M, Seitz, C, Gu, Y, Enustun, E, Suslov, S, Khanna, K, Birkholz, E.A, Amaro, R.E, Pogliano, J, Corbett, K.D, Villa, E. | Deposit date: | 2021-11-06 | Release date: | 2022-07-27 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Architecture and self-assembly of the jumbo bacteriophage nuclear shell. Nature, 608, 2022
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7SQV
| Goslar chimallin C1 localized reconstruction | Descriptor: | Chimallin | Authors: | Laughlin, T.G, Deep, A, Prichard, A.M, Seitz, C, Gu, Y, Enustun, E, Suslov, S, Khanna, K, Birkholz, E.A, Amaro, R.E, Pogliano, J, Corbett, K.D, Villa, E. | Deposit date: | 2021-11-06 | Release date: | 2022-07-27 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | Architecture and self-assembly of the jumbo bacteriophage nuclear shell. Nature, 608, 2022
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7SQU
| Goslar chimallin C4 tetramer localized reconstruction | Descriptor: | Chimallin | Authors: | Laughlin, T.G, Deep, A, Prichard, A.M, Seitz, C, Gu, Y, Enustun, E, Suslov, S, Khanna, K, Birkholz, E.A, Amaro, R.E, Pogliano, J, Corbett, K.D, Villa, E. | Deposit date: | 2021-11-06 | Release date: | 2022-07-27 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Architecture and self-assembly of the jumbo bacteriophage nuclear shell. Nature, 608, 2022
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6EF8
| Cryo-EM of the OmcS nanowires from Geobacter sulfurreducens | Descriptor: | C-type cytochrome OmcS, HEME C | Authors: | Wang, F, Gu, Y, Egelman, E.H, Malvankar, N.S. | Deposit date: | 2018-08-16 | Release date: | 2019-04-10 | Last modified: | 2019-11-27 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structure of Microbial Nanowires Reveals Stacked Hemes that Transport Electrons over Micrometers. Cell, 177, 2019
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6L31
| L1 protein of human papillomavirus 6 | Descriptor: | Major capsid protein L1 | Authors: | Li, S.W, Liu, X.L, Gu, Y. | Deposit date: | 2019-10-07 | Release date: | 2019-12-25 | Method: | ELECTRON MICROSCOPY (4.18 Å) | Cite: | Neutralization sites of human papillomavirus-6 relate to virus attachment and entry phase in viral infection. Emerg Microbes Infect, 8, 2019
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1RHH
| Crystal Structure of the Broadly HIV-1 Neutralizing Fab X5 at 1.90 Angstrom Resolution | Descriptor: | Fab X5, heavy chain, light chain | Authors: | Darbha, R, Phogat, S, Labrijn, A.F, Shu, Y, Gu, Y, Andrykovitch, M, Zhang, M.Y, Pantophlet, R, Martin, L, Vita, C, Burton, D.R, Dimitrov, D.S, Ji, X. | Deposit date: | 2003-11-14 | Release date: | 2004-02-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structure of the Broadly Cross-Reactive HIV-1-Neutralizing Fab X5 and Fine Mapping of Its Epitope Biochemistry, 43, 2004
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7TSX
| Structure of Enterobacter cloacae Cap2 bound to CdnD02 C-terminus, Apo state | Descriptor: | Cap2, Cyclic AMP-AMP-GMP synthase | Authors: | Ye, Q, Gu, Y, Ledvina, H.E, Quan, Y, Lau, R.K, Zhou, H, Whiteley, A.T, Corbett, K.D. | Deposit date: | 2022-01-31 | Release date: | 2023-01-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | An E1-E2 fusion protein primes antiviral immune signalling in bacteria. Nature, 616, 2023
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7TSQ
| Structure of Enterobacter cloacae Cap2 bound to CdnD02 C-terminus, AMP state | Descriptor: | ADENOSINE MONOPHOSPHATE, Cap2, Cyclic AMP-AMP-GMP synthase, ... | Authors: | Ye, Q, Gu, Y, Ledvina, H.E, Quan, Y, Lau, R.K, Zhou, H, Whiteley, A.T, Corbett, K.D. | Deposit date: | 2022-01-31 | Release date: | 2023-01-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | An E1-E2 fusion protein primes antiviral immune signalling in bacteria. Nature, 616, 2023
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1YY7
| Crystal structure of stringent starvation protein A (SspA), an RNA polymerase-associated transcription factor | Descriptor: | CITRIC ACID, stringent starvation protein A | Authors: | Hansen, A.-M, Gu, Y, Li, M, Andrykovitch, M, Waugh, D.S, Jin, D.J, Ji, X. | Deposit date: | 2005-02-23 | Release date: | 2005-03-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Structural basis for the function of stringent starvation protein A as a transcription factor J.Biol.Chem., 280, 2005
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7TIL
| CryoEM structure of JetD from Pseudomonas aeruginosa | Descriptor: | JetD | Authors: | Deep, A, Gu, Y, Gao, Y, Ego, K, Herzik, M, Zhou, H, Corbett, K. | Deposit date: | 2022-01-13 | Release date: | 2022-10-05 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | The SMC-family Wadjet complex protects bacteria from plasmid transformation by recognition and cleavage of closed-circular DNA. Mol.Cell, 82, 2022
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3EWH
| Crystal structure of the VEGFR2 kinase domain in complex with a pyridyl-pyrimidine benzimidazole inhibitor | Descriptor: | 1,2-ETHANEDIOL, N-[4-({3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl}oxy)naphthalen-1-yl]-6-(trifluoromethyl)-1H-benzimidazol-2-amine, vascular endothelial growth factor receptor 2 | Authors: | Whittington, D.A, Long, A.M, Rose, P, Gu, Y, Zhao, H. | Deposit date: | 2008-10-15 | Release date: | 2009-08-25 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Pyridyl-pyrimidine benzimidazole derivatives as potent, selective, and orally bioavailable inhibitors of Tie-2 kinase. Bioorg.Med.Chem.Lett., 19, 2009
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1S5O
| Structural and Mutational Characterization of L-carnitine Binding to Human carnitine Acetyltransferase | Descriptor: | CARNITINE, carnitine acetyltransferase isoform 2 | Authors: | Govindasamy, L, Kukar, T, Lian, W, Pedersen, B, Gu, Y, Agbandje-Mckenna, M, Jin, S, Mckenna, R, Wu, D. | Deposit date: | 2004-01-21 | Release date: | 2004-02-03 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural and mutational characterization of l-carnitine binding to human carnitine acetyltransferase. J.Struct.Biol., 146, 2004
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1T1U
| Structural Insights and Functional Implications of Choline Acetyltransferase | Descriptor: | Choline O-acetyltransferase | Authors: | Govindasamy, L, Pedersen, B, Lian, W, Kukar, T, Gu, Y, Jin, S, Agbandje-McKenna, M, Wu, D. | Deposit date: | 2004-04-18 | Release date: | 2005-04-12 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structural insights and functional implications of choline acetyltransferase J.Struct.Biol., 148, 2004
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1NM8
| Structure of Human Carnitine Acetyltransferase: Molecular Basis for Fatty Acyl Transfer | Descriptor: | Carnitine O-acetyltransferase | Authors: | Wu, D, Govindasamy, L, Lian, W, Gu, Y, Kukar, T, Agbandje-McKenna, M, McKenna, R. | Deposit date: | 2003-01-09 | Release date: | 2003-03-11 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of Human Carnitine Acetyltransferase. Molecular Basis for Fatty Acyl Transfer J.Biol.Chem., 278, 2003
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8DK2
| CryoEM structure of Pseudomonas aeruginosa PA14 JetABC in an unclamped state trapped in ATP dependent dimeric form | Descriptor: | DNA (26-MER), JetA, JetB, ... | Authors: | Deep, A, Gu, Y, Gao, Y, Ego, K, Herzik, M, Zhou, H, Corbett, K. | Deposit date: | 2022-07-01 | Release date: | 2022-10-05 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | The SMC-family Wadjet complex protects bacteria from plasmid transformation by recognition and cleavage of closed-circular DNA. Mol.Cell, 82, 2022
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8DK1
| CryoEM structure of JetABC (head construct) from Pseudomonas aeruginosa PA14 | Descriptor: | JetA, JetB, JetC | Authors: | Deep, A, Gu, Y, Gao, Y, Ego, K, Herzik, M, Zhou, H, Corbett, K. | Deposit date: | 2022-07-01 | Release date: | 2022-10-05 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.95 Å) | Cite: | The SMC-family Wadjet complex protects bacteria from plasmid transformation by recognition and cleavage of closed-circular DNA. Mol.Cell, 82, 2022
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8DK3
| CryoEM structure of Pseudomonas aeruginosa PA14 JetC ATPase domain bound to DNA and cWHD domain of JetA | Descriptor: | DNA (26-MER), JetA, JetC, ... | Authors: | Deep, A, Gu, Y, Gao, Y, Ego, K, Herzik, M, Zhou, H, Corbett, K. | Deposit date: | 2022-07-01 | Release date: | 2022-10-05 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.28 Å) | Cite: | The SMC-family Wadjet complex protects bacteria from plasmid transformation by recognition and cleavage of closed-circular DNA. Mol.Cell, 82, 2022
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3GGQ
| Dimerization of Hepatitis E Virus Capsid Protein E2s Domain is Essential for Virus-Host Interaction | Descriptor: | BROMIDE ION, Capsid protein | Authors: | Li, S.W, Tang, X.H, Seetharaman, J, Yang, C.Y, Gu, Y, Zhang, J, Du, H.L, Shih, J.W.K, Hew, C.L, Sivaraman, J, Xia, N.S. | Deposit date: | 2009-03-02 | Release date: | 2009-08-25 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Dimerization of hepatitis E virus capsid protein E2s domain is essential for virus-host interaction Plos Pathog., 5, 2009
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8JR9
| Small molecule agonist (PCO371) bound to human parathyroid hormone receptor type 1 (PTH1R) | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha-1, ... | Authors: | Zhao, L, He, Q, Yuan, Q, Gu, Y, He, X, Shan, H, Li, J, Wang, K, Li, Y, Hu, W, Wu, K, Shen, J, Xu, H.E. | Deposit date: | 2023-06-16 | Release date: | 2023-08-02 | Last modified: | 2023-10-04 | Method: | ELECTRON MICROSCOPY (2.57 Å) | Cite: | Conserved class B GPCR activation by a biased intracellular agonist. Nature, 621, 2023
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6IGD
| Crystal structure of HPV58/33 chimeric L1 pentamer | Descriptor: | Major capsid protein L1 | Authors: | Li, Z.H, Song, S, He, M.Z, Gu, Y, Li, S.W. | Deposit date: | 2018-09-25 | Release date: | 2018-11-21 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Rational design of a triple-type human papillomavirus vaccine by compromising viral-type specificity. Nat Commun, 9, 2018
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6IGF
| Crystal structure of Human Papillomavirus type 52 pentamer | Descriptor: | Major capsid protein L1 | Authors: | Li, Z.H, Song, S, He, M.Z, Gu, Y, Li, S.W. | Deposit date: | 2018-09-25 | Release date: | 2018-11-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.751 Å) | Cite: | Rational design of a triple-type human papillomavirus vaccine by compromising viral-type specificity. Nat Commun, 9, 2018
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