1RHH

Crystal Structure of the Broadly HIV-1 Neutralizing Fab X5 at 1.90 Angstrom Resolution

Summary for 1RHH

• Entry DOI: 10.2210/pdb1rhh/pdb
• Related: 1G9M 1G9N 1HZH 3FCT
• Descriptor: Fab X5, light chain, Fab X5, heavy chain (3 entities in total)
• Functional Keywords: fab, antibody, x5, hiv-1, broadly neutralizing, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 97381.93

Authors

Darbha, R.,Phogat, S.,Labrijn, A.F.,Shu, Y.,Gu, Y.,Andrykovitch, M.,Zhang, M.Y.,Pantophlet, R.,Martin, L.,Vita, C.,Burton, D.R.,Dimitrov, D.S.,Ji, X. (deposition date: 2003-11-14, release date: 2004-02-24, Last modification date: 2023-08-30)

• Primary citation: Darbha, R.,Phogat, S.,Labrijn, A.F.,Shu, Y.,Gu, Y.,Andrykovitch, M.,Zhang, M.Y.,Pantophlet, R.,Martin, L.,Vita, C.,Burton, D.R.,Dimitrov, D.S.,Ji, X.; Crystal Structure of the Broadly Cross-Reactive HIV-1-Neutralizing Fab X5 and Fine Mapping of Its Epitope; Biochemistry, 43:1410-1417, 2004; PubMed: 14769016; DOI: 10.1021/bi035323x

Experimental method

X-RAY DIFFRACTION (1.9 Å)