4OLY
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4TWO
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![BU of 4two by Molmil](/molmil-images/mine/4two) | Human EphA3 Kinase domain in complex with compound 164 | Descriptor: | 5-{[3-carbamoyl-4-(3,4-dimethylphenyl)-5-methylthiophen-2-yl]amino}-5-oxopentanoic acid, Ephrin type-A receptor 3 | Authors: | Dong, J, Caflisch, A. | Deposit date: | 2014-07-01 | Release date: | 2015-05-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.047 Å) | Cite: | Structural Analysis of the Binding of Type I, I1/2, and II Inhibitors to Eph Tyrosine Kinases. Acs Med.Chem.Lett., 6, 2015
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3Q6Q
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![BU of 3q6q by Molmil](/molmil-images/mine/3q6q) | Crystal Structure of P Domain from Norwalk Virus Strain Vietnam 026 in complex with disordered HBGA type Lea | Descriptor: | 1,2-ETHANEDIOL, Capsid protein, IMIDAZOLE | Authors: | Hansman, G.S, Biertumpfel, C, Chen, L, Georgiev, I, McLellan, J.S, Katayama, K, Kwong, P.D. | Deposit date: | 2011-01-03 | Release date: | 2011-05-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | Crystal structures of GII.10 and GII.12 norovirus protruding domains in complex with histo-blood group antigens reveal details for a potential site of vulnerability. J.Virol., 85, 2011
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3Q6R
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![BU of 3q6r by Molmil](/molmil-images/mine/3q6r) | Crystal Structure of P Domain from Norwalk Virus Strain Vietnam 026 in complex with disordered HBGA type Lex | Descriptor: | 1,2-ETHANEDIOL, Capsid protein, IMIDAZOLE | Authors: | Hansman, G.S, Biertumpfel, C, McLellan, J.S, Chen, L, Georgiev, I, Katayama, K, Kwong, P.D. | Deposit date: | 2011-01-03 | Release date: | 2011-05-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystal structures of GII.10 and GII.12 norovirus protruding domains in complex with histo-blood group antigens reveal details for a potential site of vulnerability. J.Virol., 85, 2011
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3U46
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![BU of 3u46 by Molmil](/molmil-images/mine/3u46) | CH04H/CH02L P212121 | Descriptor: | CH02 Light chain Fab, CH04 Heavy chain Fab | Authors: | Louder, R, Pancera, M, McLellan, J.S, Kwong, P.D. | Deposit date: | 2011-10-07 | Release date: | 2011-11-30 | Last modified: | 2011-12-21 | Method: | X-RAY DIFFRACTION (2.906 Å) | Cite: | Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9. Nature, 480, 2011
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4I3R
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![BU of 4i3r by Molmil](/molmil-images/mine/4i3r) | Crystal structure of the outer domain of HIV-1 gp120 in complex with VRC-PG04 space group P3221 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of VRC-PG04 Fab, Light chain of VRC-PG04 Fab, ... | Authors: | Joyce, M.G, Biertumpfel, C, Nabel, G.J, Kwong, P.D. | Deposit date: | 2012-11-26 | Release date: | 2013-01-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Outer Domain of HIV-1 gp120: Antigenic Optimization, Structural Malleability, and Crystal Structure with Antibody VRC-PG04. J.Virol., 87, 2013
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4GW4
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![BU of 4gw4 by Molmil](/molmil-images/mine/4gw4) | Crystal structure of 3BNC60 Fab with P61A mutation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3BNC60 Fab Heavy-chain, 3BNC60 Fab Light-chain | Authors: | Diskin, R, Fu, B.Z, Bjorkman, P.J. | Deposit date: | 2012-08-31 | Release date: | 2013-04-17 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization. Cell(Cambridge,Mass.), 153, 2013
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4I3S
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![BU of 4i3s by Molmil](/molmil-images/mine/4i3s) | Crystal structure of the outer domain of HIV-1 gp120 in complex with VRC-PG04 space group P21 | Descriptor: | CALCIUM ION, Heavy chain of VRC-PG04 Fab, Light chain of VRC-PG04 Fab, ... | Authors: | Joyce, M.G, Biertumpfel, C, Nabel, G.J, Kwong, P.D. | Deposit date: | 2012-11-26 | Release date: | 2013-01-09 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Outer Domain of HIV-1 gp120: Antigenic Optimization, Structural Malleability, and Crystal Structure with Antibody VRC-PG04. J.Virol., 87, 2013
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1QD0
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![BU of 1qd0 by Molmil](/molmil-images/mine/1qd0) | CAMELID HEAVY CHAIN VARIABLE DOMAINS PROVIDE EFFICIENT COMBINING SITES TO HAPTENS | Descriptor: | 3-HYDROXY-7-(4-{1-[2-HYDROXY-3-(2-HYDROXY-5-SULFO-PHENYLAZO)-BENZYL]-2-SULFO-ETHYLAMINO}-[1,2,5]TRIAZIN-2-YLAMINO)-2-(2-HYDROXY-5-SULFO-PHENYLAZO)-NAPTHALENE-1,8-DISULFONIC ACID, COPPER (II) ION, VHH-R2 ANTI-RR6 ANTIBODY | Authors: | Spinelli, S, Frenken, L.G.J, Hermans, P, Verrips, T, Brown, K, Tegoni, M, Cambillau, C. | Deposit date: | 1999-07-08 | Release date: | 2000-07-19 | Last modified: | 2018-02-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Camelid heavy-chain variable domains provide efficient combining sites to haptens. Biochemistry, 39, 2000
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6MQC
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![BU of 6mqc by Molmil](/molmil-images/mine/6mqc) | |
6MPH
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![BU of 6mph by Molmil](/molmil-images/mine/6mph) | Cryo-EM structure at 3.8 A resolution of HIV-1 fusion peptide-directed antibody, DF1W-a.01, elicited by vaccination of Rhesus macaques, in complex with stabilized HIV-1 Env BG505 DS-SOSIP, which was also bound to antibodies VRC03 and PGT122 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DF1W-a.01 Light chain, ... | Authors: | Acharya, P, Xu, K, Kwong, P.D. | Deposit date: | 2018-10-06 | Release date: | 2019-07-24 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019
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6MPG
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![BU of 6mpg by Molmil](/molmil-images/mine/6mpg) | Cryo-EM structure at 3.2 A resolution of HIV-1 fusion peptide-directed antibody, A12V163-b.01, elicited by vaccination of Rhesus macaques, in complex with stabilized HIV-1 Env BG505 DS-SOSIP, which was also bound to antibodies VRC03 and PGT122 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, A12V163-b.01 Heavy Chain, ... | Authors: | Acharya, P, Kwong, P.D. | Deposit date: | 2018-10-06 | Release date: | 2019-07-24 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019
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6MQE
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6MQS
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![BU of 6mqs by Molmil](/molmil-images/mine/6mqs) | |
6MQM
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![BU of 6mqm by Molmil](/molmil-images/mine/6mqm) | |
6N1W
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![BU of 6n1w by Molmil](/molmil-images/mine/6n1w) | |
6N1V
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![BU of 6n1v by Molmil](/molmil-images/mine/6n1v) | |
6NF2
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![BU of 6nf2 by Molmil](/molmil-images/mine/6nf2) | |
6MQR
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![BU of 6mqr by Molmil](/molmil-images/mine/6mqr) | Vaccine-elicited NHP FP-targeting neutralizing antibody 0PV-a.01 in complex with FP (residue 512-519) | Descriptor: | CALCIUM ION, HIV fusion peptide residue 512-519, SULFATE ION, ... | Authors: | Xu, K, Wang, Y, Kwong, P.D. | Deposit date: | 2018-10-10 | Release date: | 2019-07-31 | Last modified: | 2019-11-13 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019
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6MJZ
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![BU of 6mjz by Molmil](/molmil-images/mine/6mjz) | Cryo-EM structure of Human Parainfluenza Virus Type 3 (hPIV3) in complex with antibody PIA174 | Descriptor: | Fusion glycoprotein F0, PIA174 Fab Heavy chain, PIA174 Fab Light chain | Authors: | Acharya, P, Stewart-Jones, G, Carragher, B, Potter, C.S, Kwong, P.D. | Deposit date: | 2018-09-24 | Release date: | 2018-11-14 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structure-based design of a quadrivalent fusion glycoprotein vaccine for human parainfluenza virus types 1-4. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6N16
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2LEO
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![BU of 2leo by Molmil](/molmil-images/mine/2leo) | |
2L2O
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![BU of 2l2o by Molmil](/molmil-images/mine/2l2o) | |
2LCC
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![BU of 2lcc by Molmil](/molmil-images/mine/2lcc) | Solution structure of RBBP1 chromobarrel domain | Descriptor: | AT-rich interactive domain-containing protein 4A | Authors: | Gong, W, Feng, Y. | Deposit date: | 2011-04-28 | Release date: | 2012-02-08 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural insight into recognition of methylated histone tails by retinoblastoma-binding protein 1. J.Biol.Chem., 2012
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1KVK
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![BU of 1kvk by Molmil](/molmil-images/mine/1kvk) | The Structure of Binary complex between a Mammalian Mevalonate Kinase and ATP: Insights into the Reaction Mechanism and Human Inherited Disease | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, mevalonate kinase | Authors: | Fu, Z, Wang, M, Potter, D, Mizioko, H.M, Kim, J.J. | Deposit date: | 2002-01-26 | Release date: | 2002-03-27 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The Structure of a Binary complex
between a Mammalian Mevalonate Kinase and ATP: Insights into the
Reaction Mechanism and Human Inherited Disease J.Biol.Chem., 277, 2002
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