8BJ6
| Crystal structure of YopR | Descriptor: | SPbeta prophage-derived uncharacterized protein YopR | Authors: | Gallego del Sol, F, Marina, A. | Deposit date: | 2022-11-03 | Release date: | 2023-11-15 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Characterization of a unique repression system present in arbitrium phages of the SPbeta family. Cell Host Microbe, 31, 2023
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8BJV
| Crystal structure of YopR | Descriptor: | GLYCEROL, SPbeta prophage-derived uncharacterized protein YopR | Authors: | Gallego del Sol, F, Marina, A. | Deposit date: | 2022-11-08 | Release date: | 2023-11-22 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Characterization of a unique repression system present in arbitrium phages of the SPbeta family. Cell Host Microbe, 31, 2023
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8BPZ
| Crystal structure of YopR | Descriptor: | SPbeta prophage-derived uncharacterized protein YopR | Authors: | Gallego del Sol, F, Marina, A. | Deposit date: | 2022-11-18 | Release date: | 2023-11-29 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Characterization of a unique repression system present in arbitrium phages of the SPbeta family. Cell Host Microbe, 31, 2023
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8C8E
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8CCX
| Human SOD1 in complex with S-XL6 cross-linker | Descriptor: | COPPER (II) ION, DIMETHYL SULFOXIDE, SULFATE ION, ... | Authors: | Antonyuk, S.V, Hossain, A, Agar, J.N, Hasnain, S.S. | Deposit date: | 2023-01-27 | Release date: | 2023-12-13 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.665 Å) | Cite: | Evaluating protein cross-linking as a therapeutic strategy to stabilize SOD1 variants in a mouse model of familial ALS. Plos Biol., 22, 2024
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8D8R
| SARS-CoV-2 Spike RBD in complex with DMAb 2196 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2196 heavy chain, 2196 light chain, ... | Authors: | Du, J, Cui, J, Pallesen, J. | Deposit date: | 2022-06-08 | Release date: | 2022-10-19 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | DNA-delivered antibody cocktail exhibits improved pharmacokinetics and confers prophylactic protection against SARS-CoV-2. Nat Commun, 13, 2022
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8D8Q
| SARS-CoV-2 Spike RBD in complex with DMAbs 2130 and 2196 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2130 heavy chain, 2130 light chain, ... | Authors: | Du, J, Cui, J, Pallesen, J. | Deposit date: | 2022-06-08 | Release date: | 2022-10-19 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | DNA-delivered antibody cocktail exhibits improved pharmacokinetics and confers prophylactic protection against SARS-CoV-2. Nat Commun, 13, 2022
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8DF5
| SARS-CoV-2 Beta RBD in complex with human ACE2 and S304 Fab and S309 Fab | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | McCallum, M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Snell, G, Veesler, D. | Deposit date: | 2022-06-21 | Release date: | 2022-08-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Shifting mutational constraints in the SARS-CoV-2 receptor-binding domain during viral evolution. Science, 377, 2022
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8DIJ
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6ZCI
| Crystal structure of BRD4-BD1 in complex with NVS-BET-1 | Descriptor: | (4~{R})-4-(4-chlorophenyl)-1-cyclopropyl-5-(1,5-dimethyl-6-oxidanylidene-pyridin-3-yl)-3-methyl-4~{H}-pyrrolo[3,4-c]pyrazol-6-one, Bromodomain-containing protein 4 | Authors: | Faller, M. | Deposit date: | 2020-06-11 | Release date: | 2020-12-23 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.976 Å) | Cite: | BET bromodomain inhibitors regulate keratinocyte plasticity. Nat.Chem.Biol., 17, 2021
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1TKZ
| CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH GW429576 | Descriptor: | 6-CHLORO-4-(CYCLOHEXYLSULFANYL)-3-PROPYLQUINOLIN-2(1H)-ONE, PHOSPHATE ION, Pol polyprotein, ... | Authors: | Hopkins, A.L, Ren, J, Stuart, D.I, Stammers, D.K. | Deposit date: | 2004-06-09 | Release date: | 2004-12-07 | Last modified: | 2020-01-15 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 1. J.Med.Chem., 47, 2004
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6ZK0
| 1.47A human IMPase with ebselen | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, Inositol monophosphatase 1, ... | Authors: | Bax, B.D, Fenn, G.D. | Deposit date: | 2020-06-29 | Release date: | 2020-09-23 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Crystallization and structure of ebselen bound to Cys141 of human inositol monophosphatase. Acta Crystallogr.,Sect.F, 76, 2020
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1TXJ
| Crystal structure of translationally controlled tumour-associated protein (TCTP) from Plasmodium knowlesi | Descriptor: | translationally controlled tumour-associated protein (TCTP) from Plasmodium knowlesi, PKN_PFE0545c | Authors: | Walker, J.R, Vedadi, M, Sharma, S, Houston, S, Lew, J, Amani, M, Wasney, G, Skarina, T, Bray, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Hui, R, Structural Genomics Consortium (SGC) | Deposit date: | 2004-07-05 | Release date: | 2004-07-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms. Mol.Biochem.Parasitol., 151, 2007
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1U49
| Adenine-8oxoguanine mismatch at the polymerase active site | Descriptor: | DNA polymerase I, DNA primer strand, DNA template strand with 8-oxoguanine, ... | Authors: | Hsu, G.W, Ober, M, Carell, T, Beese, L.S. | Deposit date: | 2004-07-23 | Release date: | 2004-09-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase. Nature, 431, 2004
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1U7J
| Solution structure of a diiron protein model | Descriptor: | Four-helix bundle model, ZINC ION | Authors: | Maglio, O, Nastri, F, Calhoun, J.R, Lahr, S, Pavone, V, DeGrado, W.F, Lombardi, A. | Deposit date: | 2004-08-04 | Release date: | 2005-03-01 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Analysis and Design of Turns in alpha-Helical Hairpins J.Mol.Biol., 346, 2005
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1U48
| Extension of a cytosine-8-oxoguanine base pair | Descriptor: | DNA polymerase I, DNA primer strand, DNA template strand with 8-oxoguanine, ... | Authors: | Hsu, G.W, Ober, M, Carell, T, Beese, L.S. | Deposit date: | 2004-07-23 | Release date: | 2004-09-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase. Nature, 431, 2004
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1U45
| 8oxoguanine at the pre-insertion site of the polymerase active site | Descriptor: | DNA polymerase I, DNA primer strand, DNA template strand with 8-oxoguanine, ... | Authors: | Hsu, G.W, Ober, M, Carell, T, Beese, L.S. | Deposit date: | 2004-07-23 | Release date: | 2004-09-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase. Nature, 431, 2004
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7A3W
| Structure of Imine Reductase from Pseudomonas sp. | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, NAD(P)-dependent oxidoreductase, ... | Authors: | Cuetos, A, Thorpe, T, Turner, N.J, Grogan, G. | Deposit date: | 2020-08-18 | Release date: | 2021-08-25 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Multifunctional biocatalyst for conjugate reduction and reductive amination. Nature, 604, 2022
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6ZVP
| Atomic model of the EM-based structure of the full-length tyrosine hydroxylase in complex with dopamine (residues 40-497) in which the regulatory domain (residues 40-165) has been included only with the backbone atoms | Descriptor: | FE (III) ION, L-DOPAMINE, Tyrosine 3-monooxygenase | Authors: | Bueno-Carrasco, M.T, Cuellar, J, Santiago, C, Valpuesta, J.M, Martinez, A, Flydal, M.I. | Deposit date: | 2020-07-27 | Release date: | 2021-11-17 | Last modified: | 2022-02-02 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structural mechanism for tyrosine hydroxylase inhibition by dopamine and reactivation by Ser40 phosphorylation. Nat Commun, 13, 2022
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6ZZU
| Partial structure of the substrate-free tyrosine hydroxylase (apo-TH). | Descriptor: | FE (III) ION, Tyrosine 3-monooxygenase | Authors: | Bueno-Carrasco, M.T, Cuellar, J, Santiago, C, Valpuesta, J.M, Martinez, A, Flydal, M.I. | Deposit date: | 2020-08-05 | Release date: | 2021-11-17 | Last modified: | 2022-06-22 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural mechanism for tyrosine hydroxylase inhibition by dopamine and reactivation by Ser40 phosphorylation. Nat Commun, 13, 2022
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7A2G
| Full-length structure of the substrate-free tyrosine hydroxylase (apo-TH). | Descriptor: | FE (III) ION, Tyrosine 3-monooxygenase | Authors: | Bueno-Carrasco, M.T, Cuellar, J, Santiago, C, Flydal, M.I, Martinez, A, Valpuesta, J.M. | Deposit date: | 2020-08-17 | Release date: | 2021-12-01 | Last modified: | 2022-06-22 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural mechanism for tyrosine hydroxylase inhibition by dopamine and reactivation by Ser40 phosphorylation. Nat Commun, 13, 2022
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6ZN2
| Partial structure of tyrosine hydroxylase in complex with dopamine showing the catalytic domain and an alpha-helix from the regulatory domain involved in dopamine binding. | Descriptor: | FE (III) ION, L-DOPAMINE, SER-LEU-ILE-GLU-ASP-ALA-ARG-LYS-GLU-ARG-GLU-ALA-ALA-VAL-ALA-ALA-ALA-ALA, ... | Authors: | Bueno-Carrasco, M.T, Cuellar, J, Santiago, C, Valpuesta, J.M, Martinez, A, Flydal, M.I. | Deposit date: | 2020-07-06 | Release date: | 2021-12-08 | Last modified: | 2022-02-02 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structural mechanism for tyrosine hydroxylase inhibition by dopamine and reactivation by Ser40 phosphorylation. Nat Commun, 13, 2022
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7AUD
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7AUC
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7AQO
| yeast THO-Sub2 complex dimer | Descriptor: | BJ4_G0025130.mRNA.1.CDS.1, EM14S01-3B_G0007820.mRNA.1.CDS.1, TEX1 isoform 1, ... | Authors: | Schuller, S.K, Schuller, J.M, Prabu, R.J, Baumgartner, M, Bonneau, F, basquin, J, Conti, E. | Deposit date: | 2020-10-22 | Release date: | 2020-12-02 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structural insights into the nucleic acid remodeling mechanisms of the yeast THO-Sub2 complex. Elife, 9, 2020
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