2KJI
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![BU of 2kji by Molmil](/molmil-images/mine/2kji) | A divergent ins protein in c. elegans structurally resemble insulin and activates the human insulin receptor | Descriptor: | Probable insulin-like peptide beta-type 5 | Authors: | Hua, Q.X, Nakarawa, S.H, Wilken, R, Ramos, R.R, Jia, W.H, Bass, J, Weiss, M.A. | Deposit date: | 2009-05-28 | Release date: | 2009-06-16 | Last modified: | 2019-09-18 | Method: | SOLUTION NMR | Cite: | A divergent INS protein in Caenorhabditis elegans structurally resembles human insulin and activates the human insulin receptor. Genes Dev., 17, 2003
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8BGU
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![BU of 8bgu by Molmil](/molmil-images/mine/8bgu) | human MDM2-5S RNP | Descriptor: | 5S rRNA, 60S ribosomal protein L11, 60S ribosomal protein L5, ... | Authors: | Castillo, N, Thoms, M, Flemming, D, Hammaren, H.M, Buschauer, R, Ameismeier, M, Bassler, J, Beck, M, Beckmann, R, Hurt, E. | Deposit date: | 2022-10-28 | Release date: | 2023-06-14 | Last modified: | 2023-08-30 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structure of nascent 5S RNPs at the crossroad between ribosome assembly and MDM2-p53 pathways. Nat.Struct.Mol.Biol., 30, 2023
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7S5U
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6VPP
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![BU of 6vpp by Molmil](/molmil-images/mine/6vpp) | Cryo-EM structure of microtubule-bound KLP61F motor with tail domain in the nucleotide-free state | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein Klp61F, ... | Authors: | Bodrug, T, Wilson-Kubalek, E.M, Nithianantham, S, Debs, G, Sindelar, C.V, Milligan, R, Al-Bassam, J. | Deposit date: | 2020-02-04 | Release date: | 2020-02-19 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | The kinesin-5 tail domain directly modulates the mechanochemical cycle of the motor domain for anti-parallel microtubule sliding. Elife, 9, 2020
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6VPO
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![BU of 6vpo by Molmil](/molmil-images/mine/6vpo) | Cryo-EM structure of microtubule-bound KLP61F motor domain in the AMPPNP state | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein Klp61F, ... | Authors: | Bodrug, T, Wilson-Kubalek, E.M, Nithianantham, S, Debs, G, Sindelar, C.V, Milligan, R, Al-Bassam, J. | Deposit date: | 2020-02-04 | Release date: | 2020-02-19 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | The kinesin-5 tail domain directly modulates the mechanochemical cycle of the motor domain for anti-parallel microtubule sliding. Elife, 9, 2020
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5CYA
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![BU of 5cya by Molmil](/molmil-images/mine/5cya) | Crystal structure of Arl2 GTPase-activating protein tubulin cofactor C (TBCC) | Descriptor: | SULFATE ION, Tubulin-specific chaperone C | Authors: | Nithianantham, S, Le, S, Seto, E, Jia, W, Leary, J, Corbett, K.D, Moore, J.K, Al-Bassam, J. | Deposit date: | 2015-07-30 | Release date: | 2015-08-12 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Tubulin cofactors and Arl2 are cage-like chaperones that regulate the soluble alpha beta-tubulin pool for microtubule dynamics. Elife, 4, 2015
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6B5D
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6B5C
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4PXU
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![BU of 4pxu by Molmil](/molmil-images/mine/4pxu) | Structural basis for the assembly of the mitotic motor kinesin-5 into bipolar tetramers | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Bipolar kinesin KRP-130 | Authors: | Scholey, J.E, Nithianantham, S, Scholey, J.M, Al-Bassam, J. | Deposit date: | 2014-03-25 | Release date: | 2014-04-23 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.601 Å) | Cite: | Structural basis for the assembly of the mitotic motor Kinesin-5 into bipolar tetramers. Elife, 3, 2014
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4PXT
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2OF3
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6MZE
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6MZF
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6MZG
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![BU of 6mzg by Molmil](/molmil-images/mine/6mzg) | |
7OZS
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![BU of 7ozs by Molmil](/molmil-images/mine/7ozs) | Structure of the hexameric 5S RNP from C. thermophilum | Descriptor: | 5S rRNA, 60S ribosomal protein l5-like protein, Putative ribosomal protein, ... | Authors: | Castillo, N, Thoms, M, Flemming, D, Hammaren, H.M, Buschauer, R, Ameismeier, M, Bassler, J, Beck, M, Beckmann, R, Hurt, E. | Deposit date: | 2021-06-28 | Release date: | 2022-10-12 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of nascent 5S RNPs at the crossroad between ribosome assembly and MDM2-p53 pathways. Nat.Struct.Mol.Biol., 2023
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5JCS
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![BU of 5jcs by Molmil](/molmil-images/mine/5jcs) | CRYO-EM STRUCTURE OF THE RIX1-REA1 PRE-60S PARTICLE | Descriptor: | 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Barrio-Garcia, C, Thoms, M, Flemming, D, Kater, L, Berninghausen, O, Bassler, J, Beckmann, R, Hurt, E. | Deposit date: | 2016-04-15 | Release date: | 2016-11-16 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (9.5 Å) | Cite: | Architecture of the Rix1-Rea1 checkpoint machinery during pre-60S-ribosome remodeling Nat.Struct.Mol.Biol., 23, 2016
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5UGM
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![BU of 5ugm by Molmil](/molmil-images/mine/5ugm) | Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with Edaglitazone | Descriptor: | (5R)-5-({4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]-1-benzothiophen-7-yl}methyl)-1,3-thiazolidine-2,4-dione, Peroxisome proliferator-activated receptor gamma, nonanoic acid | Authors: | Shang, J, Kojetin, D.J. | Deposit date: | 2017-01-09 | Release date: | 2018-01-17 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPAR gamma. Elife, 7, 2018
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6ONJ
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6ONI
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![BU of 6oni by Molmil](/molmil-images/mine/6oni) | |
6PDZ
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6C1I
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![BU of 6c1i by Molmil](/molmil-images/mine/6c1i) | Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with T0070907 | Descriptor: | 2-chloro-5-nitro-N-(pyridin-4-yl)benzamide, Peroxisome proliferator-activated receptor gamma, nonanoic acid | Authors: | Shang, J, Fuhrmann, J, Brust, R, Kojetin, D.J. | Deposit date: | 2018-01-04 | Release date: | 2018-12-12 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | A structural mechanism for directing corepressor-selective inverse agonism of PPAR gamma. Nat Commun, 9, 2018
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6AUG
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6AVI
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6MD4
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6MD1
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![BU of 6md1 by Molmil](/molmil-images/mine/6md1) | |