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7D08
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BU of 7d08 by Molmil
Acinetobacter MlaFEDB complex in ATP-bound Vtrans1 conformation
Descriptor: ABC transporter ATP-binding protein, ADENOSINE-5'-TRIPHOSPHATE, Anti-sigma factor antagonist, ...
Authors:Zhang, Y.Y, Fan, Q.X, Chi, X.M, Zhou, Q, Li, Y.Y.
Deposit date:2020-09-09
Release date:2020-12-16
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Cryo-EM structures of Acinetobacter baumannii glycerophospholipid transporter.
Cell Discov, 6, 2020
7D06
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BU of 7d06 by Molmil
Cryo EM structure of the nucleotide free Acinetobacter MlaFEDB complex
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, ABC transporter ATP-binding protein, Anti-sigma factor antagonist, ...
Authors:Zhang, Y.Y, Fan, Q.X, Chi, X.M, Zhou, Q, Li, Y.Y.
Deposit date:2020-09-09
Release date:2020-12-16
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM structures of Acinetobacter baumannii glycerophospholipid transporter.
Cell Discov, 6, 2020
1H1C
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BU of 1h1c by Molmil
Histidinol-phosphate aminotransferase (HisC) from Thermotoga maritima
Descriptor: HISTIDINOL-PHOSPHATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE
Authors:Vega, M.C, Fernandez, F.J, Wilmanns, M.
Deposit date:2002-07-08
Release date:2004-03-19
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural Studies of the Catalytic Reaction Pathway of a Hyperthermophilic Histidinol-Phosphate Aminotransferase
J.Biol.Chem., 279, 2004
7E7L
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BU of 7e7l by Molmil
The crystal structure of arylacetate decarboxylase from Olsenella scatoligenes.
Descriptor: 4-HYDROXYPHENYLACETATE, Hydroxyphenylacetic acid decarboxylase
Authors:Lu, Q, Duan, Y, Zhang, Y, Yuchi, Z.
Deposit date:2021-02-26
Release date:2021-07-28
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.53 Å)
Cite:The Glycyl Radical Enzyme Arylacetate Decarboxylase from Olsenella scatoligenes
Acs Catalysis, 11, 2021
7C53
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BU of 7c53 by Molmil
Crystal Structure of SARS-CoV-2 HR1 motif in complex with pan-CoVs inhibitor EK1
Descriptor: CALCIUM ION, Spike protein S2',pan-CoVs inhibitor EK1
Authors:Zhu, Y, Yang, X, Sun, F.
Deposit date:2020-05-19
Release date:2021-05-19
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.278 Å)
Cite:Structural and functional basis for pan-CoV fusion inhibitors against SARS-CoV-2 and its variants with preclinical evaluation.
Signal Transduct Target Ther, 6, 2021
8HCT
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BU of 8hct by Molmil
Crystal structure of Cu2+ binding to Dendrorhynchus zhejiangensis ferritin
Descriptor: COPPER (II) ION, FE (III) ION, Ferritin, ...
Authors:Ming, T.H, Su, X.R, Huo, C.H.
Deposit date:2022-11-03
Release date:2023-03-29
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Structural and Biochemical Characterization of Silver/Copper Binding by Dendrorhynchus zhejiangensis Ferritin.
Polymers (Basel), 15, 2023
6I5Z
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BU of 6i5z by Molmil
Papaver somniferum O-methyltransferase
Descriptor: O-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE, S-ADENOSYLMETHIONINE
Authors:Davies, G.J, Cabry, M.P, Offen, W.A.
Deposit date:2018-11-15
Release date:2019-03-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of Papaver somniferum O-Methyltransferase 1 Reveals Initiation of Noscapine Biosynthesis with Implications for Plant Natural Product Methylation
Acs Catalysis, 2019
6IXQ
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BU of 6ixq by Molmil
Structure of Myo2-GTD in complex with Smy1
Descriptor: Kinesin-related protein SMY1, Myosin-2
Authors:Tang, K, Wei, Z.
Deposit date:2018-12-11
Release date:2019-03-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.06 Å)
Cite:Structural mechanism for versatile cargo recognition by the yeast class V myosin Myo2.
J.Biol.Chem., 294, 2019
8HQN
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BU of 8hqn by Molmil
Activation mechanism of GPR132 by 9(S)-HODE
Descriptor: (9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Wang, J.L, Ding, J.H, Sun, J.P, Yu, X.
Deposit date:2022-12-13
Release date:2023-10-11
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Functional screening and rational design of compounds targeting GPR132 to treat diabetes.
Nat Metab, 5, 2023
1K94
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BU of 1k94 by Molmil
Crystal structure of des(1-52)grancalcin with bound calcium
Descriptor: CALCIUM ION, GRANCALCIN
Authors:Jia, J, Borregaard, N, Lollike, K, Cygler, M.
Deposit date:2001-10-26
Release date:2001-12-07
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of Ca(2+)-loaded human grancalcin.
Acta Crystallogr.,Sect.D, 57, 2001
8HVI
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BU of 8hvi by Molmil
Activation mechanism of GPR132 by compound NOX-6-7
Descriptor: 3-methyl-5-[(4-oxidanylidene-4-phenyl-butanoyl)amino]-1-benzofuran-2-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Wang, J.L, Ding, J.H, Sun, J.P, Yu, X.
Deposit date:2022-12-26
Release date:2023-10-11
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Functional screening and rational design of compounds targeting GPR132 to treat diabetes.
Nat Metab, 5, 2023
8HQE
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BU of 8hqe by Molmil
Cryo-EM structure of the apo-GPR132-Gi
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Wang, J.L, Ding, J.H, Sun, J.P, Yu, X.
Deposit date:2022-12-13
Release date:2023-10-11
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:Functional screening and rational design of compounds targeting GPR132 to treat diabetes.
Nat Metab, 5, 2023
1K95
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BU of 1k95 by Molmil
Crystal structure of des(1-52)grancalcin with bound calcium
Descriptor: GRANCALCIN
Authors:Jia, J, Borregaard, N, Lollike, K, Cygler, M.
Deposit date:2001-10-26
Release date:2001-12-07
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of Ca(2+)-loaded human grancalcin.
Acta Crystallogr.,Sect.D, 57, 2001
8HQM
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BU of 8hqm by Molmil
Activation mechanism of GPR132 by NPGLY
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Wang, J.L, Ding, J.H, Sun, J.P, Yu, X.
Deposit date:2022-12-13
Release date:2023-10-11
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Functional screening and rational design of compounds targeting GPR132 to treat diabetes.
Nat Metab, 5, 2023
6IXR
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BU of 6ixr by Molmil
Structure of Myo2-GTD in complex with Inp2
Descriptor: Inheritance of peroxisomes protein 2, Myosin-2, SULFATE ION
Authors:Tang, K, Wei, Z.
Deposit date:2018-12-11
Release date:2019-03-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.854 Å)
Cite:Structural mechanism for versatile cargo recognition by the yeast class V myosin Myo2.
J.Biol.Chem., 294, 2019
6J99
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BU of 6j99 by Molmil
Cryo-EM structure of human DOT1L in complex with an H2B-monoubiquitinated nucleosome
Descriptor: DNA (144-MER), DNA (145-MER), Histone H2A, ...
Authors:Yao, T, Huang, J.
Deposit date:2019-01-22
Release date:2019-02-27
Last modified:2019-04-10
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural basis of the crosstalk between histone H2B monoubiquitination and H3 lysine 79 methylation on nucleosome.
Cell Res., 29, 2019
7E5Y
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BU of 7e5y by Molmil
Molecular basis for neutralizing antibody 2B11 targeting SARS-CoV-2 RBD
Descriptor: 2B11 Fab Heavy chain, 2B11 Fab Light chain, Spike protein S1
Authors:Wu, H, Yu, F, Wang, Q.S, Zhou, H, Wang, W.W, Zhao, T, Pan, Y.B, Yang, X.M.
Deposit date:2021-02-21
Release date:2021-06-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.59 Å)
Cite:Screening of potent neutralizing antibodies against SARS-CoV-2 using convalescent patients-derived phage-display libraries.
Cell Discov, 7, 2021
6IXO
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BU of 6ixo by Molmil
Apo structure of Myo2-GTD
Descriptor: CHLORIDE ION, Myosin-2, SULFATE ION
Authors:Tang, K, Wei, Z.
Deposit date:2018-12-11
Release date:2019-03-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Structural mechanism for versatile cargo recognition by the yeast class V myosin Myo2.
J.Biol.Chem., 294, 2019
6IXP
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BU of 6ixp by Molmil
Structure of Myo2-GTD in complex with Mmr1
Descriptor: Mitochondrial MYO2 receptor-related protein 1, Myosin-2
Authors:Tang, K, Wei, Z.
Deposit date:2018-12-11
Release date:2019-03-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.733 Å)
Cite:Structural mechanism for versatile cargo recognition by the yeast class V myosin Myo2.
J.Biol.Chem., 294, 2019
7D0C
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BU of 7d0c by Molmil
S protein of SARS-CoV-2 in complex bound with P5A-3A1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of P5A-3A1, ...
Authors:Yan, R.H, Wang, R.K, Yu, J.F, Zhang, Y.Y, Liu, N, Wang, H.W, Wang, X.Q, Zhang, L.Q, Zhou, Q.
Deposit date:2020-09-09
Release date:2021-03-10
Last modified:2021-05-19
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis for bivalent binding and inhibition of SARS-CoV-2 infection by human potent neutralizing antibodies.
Cell Res., 31, 2021
7D0B
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BU of 7d0b by Molmil
S protein of SARS-CoV-2 in complex bound with P5A-3C12_1B
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of P5A-3C12, ...
Authors:Yan, R.H, Wang, R.K, Ju, B, Yu, J.F, Zhang, Y.Y, Liu, N, Wang, H.W, Wang, X.Q, Zhang, L.Q, Zhou, Q.
Deposit date:2020-09-09
Release date:2021-03-10
Last modified:2021-05-19
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis for bivalent binding and inhibition of SARS-CoV-2 infection by human potent neutralizing antibodies.
Cell Res., 31, 2021
7D0D
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BU of 7d0d by Molmil
S protein of SARS-CoV-2 in complex bound with P5A-3C12_2B
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of P5A-3C12, ...
Authors:Yan, R.H, Wang, R.K, Ju, B, Yu, J.F, Zhang, Y.Y, Liu, N, Wang, H.W, Wang, X.Q, Zhang, L.Q, Zhou, Q.
Deposit date:2020-09-09
Release date:2021-03-10
Last modified:2021-05-19
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis for bivalent binding and inhibition of SARS-CoV-2 infection by human potent neutralizing antibodies.
Cell Res., 31, 2021
7VCQ
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BU of 7vcq by Molmil
structure of viral protein BKRF4 in complex with H3.3-H4-ASF1
Descriptor: Histone H3.3, Histone H4, Histone chaperone ASF1B, ...
Authors:Liu, Y.R.
Deposit date:2021-09-03
Release date:2022-08-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Epstein-Barr Virus Tegument Protein BKRF4 is a Histone Chaperone.
J.Mol.Biol., 434, 2022
7VCL
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BU of 7vcl by Molmil
structure of viral protein BKRF4 in complex with H2A-H2B
Descriptor: Tegument protein BKRF4, histone H2A-H2B
Authors:Liu, Y.R.
Deposit date:2021-09-03
Release date:2022-08-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Epstein-Barr Virus Tegument Protein BKRF4 is a Histone Chaperone.
J.Mol.Biol., 434, 2022
6K9H
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BU of 6k9h by Molmil
Human LXR-beta in complex with an agonist
Descriptor: Oxysterols receptor LXR-beta, ~{tert}-butyl (2'~{S},3~{S})-2-oxidanylidene-2'-phenyl-spiro[1~{H}-indole-3,3'-pyrrolidine]-1'-carboxylate
Authors:Zhang, Z, Zhou, H.
Deposit date:2019-06-15
Release date:2020-04-22
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Discovery of new LXR beta agonists as glioblastoma inhibitors.
Eur.J.Med.Chem., 194, 2020

222415

数据于2024-07-10公开中

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