7C53
Crystal Structure of SARS-CoV-2 HR1 motif in complex with pan-CoVs inhibitor EK1
Summary for 7C53
Entry DOI | 10.2210/pdb7c53/pdb |
Descriptor | Spike protein S2',pan-CoVs inhibitor EK1, CALCIUM ION (3 entities in total) |
Functional Keywords | sars-cov-2 hr1, pan-covs inhibitor, ek1 peptide, virus, viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) More |
Total number of polymer chains | 6 |
Total formula weight | 70040.53 |
Authors | |
Primary citation | Xia, S.,Lan, Q.,Zhu, Y.,Wang, C.,Xu, W.,Li, Y.,Wang, L.,Jiao, F.,Zhou, J.,Hua, C.,Wang, Q.,Cai, X.,Wu, Y.,Gao, J.,Liu, H.,Sun, G.,Munch, J.,Kirchhoff, F.,Yuan, Z.,Xie, Y.,Sun, F.,Jiang, S.,Lu, L. Structural and functional basis for pan-CoV fusion inhibitors against SARS-CoV-2 and its variants with preclinical evaluation. Signal Transduct Target Ther, 6:288-288, 2021 Cited by PubMed: 34326308DOI: 10.1038/s41392-021-00712-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.278 Å) |
Structure validation
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