7C53

Crystal Structure of SARS-CoV-2 HR1 motif in complex with pan-CoVs inhibitor EK1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016020	cellular_component	membrane
A	0019031	cellular_component	viral envelope
A	0019064	biological_process	fusion of virus membrane with host plasma membrane
A	0039654	biological_process	fusion of virus membrane with host endosome membrane
A	0046813	biological_process	receptor-mediated virion attachment to host cell
A	0055036	cellular_component	virion membrane
A	0075509	biological_process	endocytosis involved in viral entry into host cell
B	0016020	cellular_component	membrane
B	0019031	cellular_component	viral envelope
B	0019064	biological_process	fusion of virus membrane with host plasma membrane
B	0039654	biological_process	fusion of virus membrane with host endosome membrane
B	0046813	biological_process	receptor-mediated virion attachment to host cell
B	0055036	cellular_component	virion membrane
B	0075509	biological_process	endocytosis involved in viral entry into host cell
C	0016020	cellular_component	membrane
C	0019031	cellular_component	viral envelope
C	0019064	biological_process	fusion of virus membrane with host plasma membrane
C	0039654	biological_process	fusion of virus membrane with host endosome membrane
C	0046813	biological_process	receptor-mediated virion attachment to host cell
C	0055036	cellular_component	virion membrane
C	0075509	biological_process	endocytosis involved in viral entry into host cell
D	0016020	cellular_component	membrane
D	0019031	cellular_component	viral envelope
D	0019064	biological_process	fusion of virus membrane with host plasma membrane
D	0039654	biological_process	fusion of virus membrane with host endosome membrane
D	0046813	biological_process	receptor-mediated virion attachment to host cell
D	0055036	cellular_component	virion membrane
D	0075509	biological_process	endocytosis involved in viral entry into host cell
E	0016020	cellular_component	membrane
E	0019031	cellular_component	viral envelope
E	0019064	biological_process	fusion of virus membrane with host plasma membrane
E	0039654	biological_process	fusion of virus membrane with host endosome membrane
E	0046813	biological_process	receptor-mediated virion attachment to host cell
E	0055036	cellular_component	virion membrane
E	0075509	biological_process	endocytosis involved in viral entry into host cell
F	0016020	cellular_component	membrane
F	0019031	cellular_component	viral envelope
F	0019064	biological_process	fusion of virus membrane with host plasma membrane
F	0039654	biological_process	fusion of virus membrane with host endosome membrane
F	0046813	biological_process	receptor-mediated virion attachment to host cell
F	0055036	cellular_component	virion membrane
F	0075509	biological_process	endocytosis involved in viral entry into host cell

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue CA D 1101

Chain	Residue
A	HOH1102
D	ASP950
D	HOH1206

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site_id	AC2
Number of Residues	5
Details	binding site for residue CA E 1101

Chain	Residue
E	ASP1032
E	LEU1033
E	GLU1035
E	HOH1206
E	HOH1226

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