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3KXI
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BU of 3kxi by Molmil
crystal structure of SsGBP and GDP complex
Descriptor: GTP-binding protein (HflX), GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Huang, B, Li, X, Zhang, X.C, Rao, Z.
Deposit date:2009-12-03
Release date:2010-05-26
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Functional study on GTP hydrolysis by the GTP binding protein from Sulfolobus solfataricus, a member of the HflX family.
J.Biochem., 2010
3KXK
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BU of 3kxk by Molmil
Crystal structure of SsGBP mutation variant G235P
Descriptor: GTP-binding protein (HflX)
Authors:Huang, B, Li, X, Zhang, X.C, Rao, Z.
Deposit date:2009-12-03
Release date:2010-05-26
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Functional study on GTP hydrolysis by the GTP binding protein from Sulfolobus solfataricus, a member of the HflX family.
J.Biochem., 2010
6E7P
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BU of 6e7p by Molmil
cryo-EM structure of human TRPML1 with PI35P2
Descriptor: (1R,2S,3S,4R,5S,6R)-5-{[(R)-[(2R)-2,3-bis{[(1S)-1-hydroxyoctyl]oxy}propoxy](hydroxy)phosphoryl]oxy}-2,4,6-trihydroxycyclohexane-1,3-diyl bis[dihydrogen (phosphate)], Mucolipin-1
Authors:Schmiege, P, Li, X.
Deposit date:2018-07-27
Release date:2018-11-28
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis for PtdInsP2-mediated human TRPML1 regulation.
Nat Commun, 9, 2018
6E7Y
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BU of 6e7y by Molmil
cryo-EM structure of human TRPML1 with PI45P2
Descriptor: Mucolipin-1, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
Authors:Schmiege, P, Li, X.
Deposit date:2018-07-27
Release date:2018-11-28
Method:ELECTRON MICROSCOPY (3.57 Å)
Cite:Structural basis for PtdInsP2-mediated human TRPML1 regulation.
Nat Commun, 9, 2018
6E7Z
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BU of 6e7z by Molmil
cryo-EM structure of human TRPML1 with ML-SA1 and PI35P2
Descriptor: (1R,2S,3S,4R,5S,6R)-5-{[(R)-[(2R)-2,3-bis{[(1S)-1-hydroxyoctyl]oxy}propoxy](hydroxy)phosphoryl]oxy}-2,4,6-trihydroxycyclohexane-1,3-diyl bis[dihydrogen (phosphate)], 2-{2-oxo-2-[(4S)-2,2,4-trimethyl-3,4-dihydroquinolin-1(2H)-yl]ethyl}-1H-isoindole-1,3(2H)-dione, Mucolipin-1
Authors:Schmiege, P, Li, X.
Deposit date:2018-07-27
Release date:2018-11-28
Method:ELECTRON MICROSCOPY (3.73 Å)
Cite:Structural basis for PtdInsP2-mediated human TRPML1 regulation.
Nat Commun, 9, 2018
5JYY
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BU of 5jyy by Molmil
Structure-based Tetravalent Zanamivir with Potent Inhibitory Activity against Drug-resistant Influenza Viruses
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-acetamido-2,6-anhydro-4-carbamimidamido-3,4,5-trideoxy-7-O-[(2-methoxyethyl)carbamoyl]-D-glycero-D-galacto-non-2-enon ic acid, CALCIUM ION, ...
Authors:Fu, L, Wu, Y, Bi, Y, Zhang, S, Lv, X, Qi, J, Li, Y, Lu, X, Yan, J, Gao, G.F, Li, X.
Deposit date:2016-05-15
Release date:2016-06-29
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure-Based Tetravalent Zanamivir with Potent Inhibitory Activity against Drug-Resistant Influenza Viruses
J.Med.Chem., 59, 2016
7P5R
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BU of 7p5r by Molmil
Racemic protein crystal structure of lacticin Q from Lactococcus lactis
Descriptor: D-Lacticin Q, FORMIC ACID, Lacticin Q
Authors:Lander, A.J, Li, X, Baumann, P, Rizkallah, P, Luk, L.Y.P, Jin, Y.
Deposit date:2021-07-14
Release date:2022-07-27
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (0.96 Å)
Cite:Roles of inter- and intramolecular tryptophan interactions in membrane-active proteins revealed by racemic protein crystallography.
Commun Chem, 6, 2023
7TBW
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BU of 7tbw by Molmil
The structure of ATP-bound ABCA1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Sun, Y, Li, X.
Deposit date:2021-12-22
Release date:2022-01-26
Last modified:2023-05-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cholesterol efflux mechanism revealed by structural analysis of human ABCA1 conformational states.
Nat Cardiovasc Res, 1, 2022
7TC0
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BU of 7tc0 by Molmil
The structure of human ABCA1 in digitonin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ATP-binding cassette, ...
Authors:Sun, Y, Li, X.
Deposit date:2021-12-22
Release date:2022-01-26
Last modified:2023-05-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cholesterol efflux mechanism revealed by structural analysis of human ABCA1 conformational states.
Nat Cardiovasc Res, 1, 2022
7TBZ
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BU of 7tbz by Molmil
The structure of ABCA1 Y482C
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ATP-binding cassette, ...
Authors:Sun, Y, Li, X.
Deposit date:2021-12-22
Release date:2022-01-26
Last modified:2023-05-24
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Cholesterol efflux mechanism revealed by structural analysis of human ABCA1 conformational states.
Nat Cardiovasc Res, 1, 2022
7TBY
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BU of 7tby by Molmil
The structure of human ABCA1 in nanodisc
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ATP-binding cassette, ...
Authors:Sun, Y, Li, X.
Deposit date:2021-12-22
Release date:2022-01-26
Last modified:2023-05-24
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Cholesterol efflux mechanism revealed by structural analysis of human ABCA1 conformational states.
Nat Cardiovasc Res, 1, 2022
5XRA
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BU of 5xra by Molmil
Crystal structure of the human CB1 in complex with agonist AM11542
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (6aR,10aR)-3-(8-bromanyl-2-methyl-octan-2-yl)-6,6,9-trimethyl-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol, CHOLESTEROL, ...
Authors:Hua, T, Vemuri, K, Nikas, P.S, Laprairie, R.B, Wu, Y, Qu, L, Pu, M, Korde, A, Shan, J, Ho, J.H, Han, G.W, Ding, K, Li, X, Liu, H, Hanson, M.A, Zhao, S, Bohn, L.M, Makriyannis, A, Stevens, R.C, Liu, Z.J.
Deposit date:2017-06-08
Release date:2017-07-12
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of agonist-bound human cannabinoid receptor CB1
Nature, 547, 2017
7RR5
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BU of 7rr5 by Molmil
Structure of ribosomal complex bound with Rbg1/Tma46
Descriptor: 18S rRNA, 25S rRNA, 40S ribosomal protein S0, ...
Authors:Zeng, F, Li, X, Pires-Alves, M, Chen, X, Hawk, C.W, Jin, H.
Deposit date:2021-08-09
Release date:2021-11-10
Method:ELECTRON MICROSCOPY (3.23 Å)
Cite:Conserved heterodimeric GTPase Rbg1/Tma46 promotes efficient translation in eukaryotic cells.
Cell Rep, 37, 2021
6WEK
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BU of 6wek by Molmil
Structure of cGMP-bound WT TAX-4 reconstituted in lipid nanodiscs
Descriptor: 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CYCLIC GUANOSINE MONOPHOSPHATE, ...
Authors:Zheng, X, Fu, Z, Su, D, Zhang, Y, Li, M, Pan, Y, Li, H, Li, S, Grassucci, R.A, Ren, Z, Hu, Z, Li, X, Zhou, M, Li, G, Frank, J, Yang, J.
Deposit date:2020-04-02
Release date:2020-06-03
Last modified:2020-07-22
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Mechanism of ligand activation of a eukaryotic cyclic nucleotide-gated channel.
Nat.Struct.Mol.Biol., 27, 2020
6WEL
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BU of 6wel by Molmil
Structure of cGMP-unbound F403V/V407A mutant TAX-4 reconstituted in lipid nanodiscs
Descriptor: 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Cyclic nucleotide-gated cation channel, ...
Authors:Zheng, X, Fu, Z, Su, D, Zhang, Y, Li, M, Pan, Y, Li, H, Li, S, Grassucci, R.A, Ren, Z, Hu, Z, Li, X, Zhou, M, Li, G, Frank, J, Yang, J.
Deposit date:2020-04-02
Release date:2020-06-03
Last modified:2020-07-22
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Mechanism of ligand activation of a eukaryotic cyclic nucleotide-gated channel.
Nat.Struct.Mol.Biol., 27, 2020
6WEJ
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BU of 6wej by Molmil
Structure of cGMP-unbound WT TAX-4 reconstituted in lipid nanodiscs
Descriptor: 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Cyclic nucleotide-gated cation channel, ...
Authors:Zheng, X, Fu, Z, Su, D, Zhang, Y, Li, M, Pan, Y, Li, H, Li, S, Grassucci, R.A, Ren, Z, Hu, Z, Li, X, Zhou, M, Li, G, Frank, J, Yang, J.
Deposit date:2020-04-02
Release date:2020-06-03
Last modified:2020-07-22
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Mechanism of ligand activation of a eukaryotic cyclic nucleotide-gated channel.
Nat.Struct.Mol.Biol., 27, 2020
4RM0
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BU of 4rm0 by Molmil
Crystal structure of Norovirus OIF P domain in complex with Lewis a trisaccharide
Descriptor: Capsid protein, beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-alpha-D-glucopyranose, beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Liu, W, Chen, Y, Tan, M, Xia, M, Li, X, Jiang, X, Rao, Z.
Deposit date:2014-10-18
Release date:2015-06-24
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:A Unique Human Norovirus Lineage with a Distinct HBGA Binding Interface.
Plos Pathog., 11, 2015
4RLZ
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BU of 4rlz by Molmil
Crystal structure of Norovirus OIF P domain
Descriptor: Capsid protein, GLYCEROL
Authors:Liu, W, Chen, Y, Tan, M, Xia, M, Li, X, Jiang, X, Rao, Z.
Deposit date:2014-10-18
Release date:2015-06-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.19 Å)
Cite:A Unique Human Norovirus Lineage with a Distinct HBGA Binding Interface.
Plos Pathog., 11, 2015
4UIS
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BU of 4uis by Molmil
The cryoEM structure of human gamma-Secretase complex
Descriptor: GAMMA-SECRETASE, LYSOZYME
Authors:Sun, L, Zhao, L, Yang, G, Yan, C, Zhou, R, Zhou, X, Xie, T, Zhao, Y, Wu, S, Li, X, Shi, Y.
Deposit date:2015-04-03
Release date:2015-06-10
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structural Basis of Human Gamma-Secretase Assembly.
Proc.Natl.Acad.Sci.USA, 112, 2015
6LH8
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BU of 6lh8 by Molmil
Structure of aerolysin-like protein (Bombina maxima)
Descriptor: aerolysin-like protein
Authors:Bian, X.L, Wang, Q.Q, Li, X, Teng, M.Q, Zhang, Y.
Deposit date:2019-12-07
Release date:2020-06-10
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.729 Å)
Cite:A cellular endolysosome-modulating pore-forming protein from a toad is negatively regulated by its paralog under oxidizing conditions.
J.Biol.Chem., 295, 2020
6LHZ
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BU of 6lhz by Molmil
Structure of aerolysin-like protein (Bombina maxima)
Descriptor: aerolysin-like protein
Authors:Bian, X.L, Wang, Q.Q, Li, X, Teng, M.Q, Zhang, Y.
Deposit date:2019-12-10
Release date:2020-06-10
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:A cellular endolysosome-modulating pore-forming protein from a toad is negatively regulated by its paralog under oxidizing conditions.
J.Biol.Chem., 295, 2020
5ADY
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BU of 5ady by Molmil
Cryo-EM structures of the 50S ribosome subunit bound with HflX
Descriptor: 23S RRNA, 50S RIBOSOMAL PROTEIN L1, 50S RIBOSOMAL PROTEIN L10, ...
Authors:Zhang, Y, Mandava, C.S, Cao, W, Li, X, Zhang, D, Li, N, Zhang, Y, Zhang, X, Qin, Y, Mi, K, Lei, J, Sanyal, S, Gao, N.
Deposit date:2015-08-25
Release date:2015-10-14
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Hflx is a Ribosome Splitting Factor Rescuing Stalled Ribosomes Under Stress Conditions
Nat.Struct.Mol.Biol., 22, 2015
4I8B
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BU of 4i8b by Molmil
Crystal Structure of Thioredoxin from Schistosoma Japonicum
Descriptor: Thioredoxin
Authors:Wu, Q, Peng, Y, Zhao, J, Li, X, Fan, X, Zhou, X, Chen, J, Luo, Z, Shi, D.
Deposit date:2012-12-03
Release date:2013-12-04
Last modified:2015-06-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Expression, characterization and crystal structure of thioredoxin from Schistosoma japonicum.
Parasitology, 142, 2015
3AQQ
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BU of 3aqq by Molmil
Crystal structure of human CRHSP-24
Descriptor: Calcium-regulated heat stable protein 1
Authors:Hou, H, Wang, F, Zhang, W, Wang, D, Li, X, Bartlam, M, Yao, X, Rao, Z.
Deposit date:2010-11-17
Release date:2010-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.798 Å)
Cite:CRHSP-24 is a novel cargo adaptor trafficking between stress granules and processing bodies
To be Published
8WYI
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BU of 8wyi by Molmil
T cell receptor delta 2 gamma 9 with TCRD TM domain chimera of TRAC
Descriptor: Signal peptide,flag tag,T cell receptor delta variable 2,T cell receptor delta constant,T cell receptor alpha chain constant,T cell receptor delta variable 2,T cell receptor delta constant,T cell receptor alpha chain constant, Signal peptide,flag tag,T cell receptor gamma variable 9,T cell receptor gamma constant 1,T cell receptor gamma variable 9,T cell receptor gamma constant 1, T-cell surface glycoprotein CD3 delta chain, ...
Authors:Xin, W, Huang, B, Chi, X, Liu, Y, Xu, M, Zhang, Y, Li, X, Su, Q, Zhou, Q.
Deposit date:2023-10-31
Release date:2024-05-08
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structures of human gamma delta T cell receptor-CD3 complex.
Nature, 2024

221051

数据于2024-06-12公开中

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