Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
8XJK
DownloadVisualize
BU of 8xjk by Molmil
Cloprosetnol bound Prostaglandin F2-alpha receptor-Gq Protein Complex
Descriptor: Antibody fragment scFv16, Cloprostenol, Engineered miniGq, ...
Authors:Zhang, X, Li, X, Liu, G, Gong, W.
Deposit date:2023-12-21
Release date:2024-02-28
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (2.63 Å)
Cite:Structural basis for ligand recognition and activation of the prostanoid receptors.
Cell Rep, 43, 2024
8XJO
DownloadVisualize
BU of 8xjo by Molmil
U46619 bound Thromboxane A2 receptor-Gq Protein Complex
Descriptor: (5Z)-7-{(1R,4S,5S,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid, Antibody fragment scFv16, Engineered miniGq, ...
Authors:Zhang, X, Li, X, Liu, G, Gong, W.
Deposit date:2023-12-21
Release date:2024-02-28
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (3.11 Å)
Cite:Structural basis for ligand recognition and activation of the prostanoid receptors.
Cell Rep, 43, 2024
8XJM
DownloadVisualize
BU of 8xjm by Molmil
Latanoprost acid bound Prostaglandin F2-alpha receptor-Gq Protein Complex
Descriptor: Antibody fragment scFv16, Engineered miniGq, Fusion tag,Prostaglandin F2-alpha receptor,LgBiT, ...
Authors:Zhang, X, Li, X, Liu, G, Gong, W.
Deposit date:2023-12-21
Release date:2024-02-28
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Structural basis for ligand recognition and activation of the prostanoid receptors.
Cell Rep, 43, 2024
8KIE
DownloadVisualize
BU of 8kie by Molmil
Structure of YchF with 50S ribosomal subunit (local map)
Descriptor: 23S rRNA (partial), 50S ribosomal protein L14, 50S ribosomal protein L19, ...
Authors:Yu, T, Li, X, Zeng, F.
Deposit date:2023-08-23
Release date:2024-08-28
Last modified:2025-06-25
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structure basis of translation regulation by YchF bound to ribosome
To Be Published
8YRY
DownloadVisualize
BU of 8yry by Molmil
HER3 in complex with FAb Hu3f8
Descriptor: Receptor tyrosine-protein kinase erbB-3, fab Hu3f8 heavy chain, fab Hu3f8 light chain
Authors:Wang, M, Li, X.
Deposit date:2024-03-22
Release date:2025-06-25
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:DB-1310,a novel HER3-targeting antibody-drug conjugate,shows synergistic antitumor activity with trastuzumab in breast cancer
To Be Published
7W7F
DownloadVisualize
BU of 7w7f by Molmil
Cryo-EM structure of human NaV1.3/beta1/beta2-ICA121431
Descriptor: (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 2,2-diphenyl-~{N}-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]ethanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Jiang, D, Li, X.
Deposit date:2021-12-04
Release date:2022-04-06
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Structural basis for modulation of human Na V 1.3 by clinical drug and selective antagonist.
Nat Commun, 13, 2022
7W77
DownloadVisualize
BU of 7w77 by Molmil
cryo-EM structure of human NaV1.3/beta1/beta2-bulleyaconitineA
Descriptor: (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Jiang, D, Li, X.
Deposit date:2021-12-03
Release date:2022-04-06
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis for modulation of human Na V 1.3 by clinical drug and selective antagonist.
Nat Commun, 13, 2022
8ZDY
DownloadVisualize
BU of 8zdy by Molmil
Cryo-EM structure of Cas8-HNH system at target free state
Descriptor: RNA (58-MER), a protein
Authors:Zhang, H, Zhu, H, Li, X, Liu, Y.
Deposit date:2024-05-03
Release date:2024-10-02
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural basis for the type I-F Cas8-HNH system.
Embo J., 43, 2024
8ZNR
DownloadVisualize
BU of 8znr by Molmil
Cryo-EM structure of Cas8-HNH system at ssDNA-bound state
Descriptor: DNA (35-MER), RNA (56-MER), protein structure
Authors:Zhang, H, Zhu, H, Li, X, Liu, Y.
Deposit date:2024-05-28
Release date:2024-10-02
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis for the type I-F Cas8-HNH system.
Embo J., 43, 2024
8Z0L
DownloadVisualize
BU of 8z0l by Molmil
Cryo-EM structure of Cas8-HNH system at partial R-loop state
Descriptor: DNA (32-MER), DNA (5'-D(P*GP*TP*GP*CP*GP*GP*A)-3'), HNH endonuclease, ...
Authors:Zhang, H, Zhu, H, Li, X, Liu, Y.
Deposit date:2024-04-09
Release date:2024-10-02
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (2.57 Å)
Cite:Structural basis for the type I-F Cas8-HNH system.
Embo J., 43, 2024
8Z0K
DownloadVisualize
BU of 8z0k by Molmil
Cryo-EM structure of Cas8-HNH system at full R-loop state
Descriptor: DNA (37-MER), DNA (5'-D(P*GP*TP*GP*CP*GP*GP*A)-3'), HNH endonuclease, ...
Authors:Zhang, H, Zhu, H, Li, X, Liu, Y.
Deposit date:2024-04-09
Release date:2024-10-02
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (2.51 Å)
Cite:Structural basis for the type I-F Cas8-HNH system.
Embo J., 43, 2024
8ZDR
DownloadVisualize
BU of 8zdr by Molmil
Cryo-EM structure of the Cas9d-sgRNA-target DNA complex
Descriptor: DNA (32-MER), DNA (5'-D(P*CP*GP*GP*GP*TP*CP*AP*AP*AP*TP*G)-3'), RNA (144-MER), ...
Authors:Zhang, H, Li, X, Liu, Z.
Deposit date:2024-05-03
Release date:2025-02-19
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (2.65 Å)
Cite:Cryo-EM structure of the Cas9d-sgRNA-target DNA complex
To Be Published
8ZQ9
DownloadVisualize
BU of 8zq9 by Molmil
Cryo-EM structure of the Cas9d-sgRNA complex
Descriptor: RNA (128-MER), ZINC ION, a protein
Authors:Zhang, H, Li, X, Liu, Z.
Deposit date:2024-06-01
Release date:2025-02-05
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (2.87 Å)
Cite:Cryo-EM structure of the Cas9d-sgRNA complex
To Be Published
3CTM
DownloadVisualize
BU of 3ctm by Molmil
Crystal Structure of a Carbonyl Reductase from Candida Parapsilosis with anti-Prelog Stereo-specificity
Descriptor: Carbonyl Reductase
Authors:Zhang, R, Zhu, G, Li, X, Xu, Y, Zhang, X.C, Rao, Z.
Deposit date:2008-04-14
Release date:2008-05-27
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Crystal structure of a carbonyl reductase from Candida parapsilosis with anti-Prelog stereospecificity.
Protein Sci., 17, 2008
5JYY
DownloadVisualize
BU of 5jyy by Molmil
Structure-based Tetravalent Zanamivir with Potent Inhibitory Activity against Drug-resistant Influenza Viruses
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-acetamido-2,6-anhydro-4-carbamimidamido-3,4,5-trideoxy-7-O-[(2-methoxyethyl)carbamoyl]-D-glycero-D-galacto-non-2-enon ic acid, CALCIUM ION, ...
Authors:Fu, L, Wu, Y, Bi, Y, Zhang, S, Lv, X, Qi, J, Li, Y, Lu, X, Yan, J, Gao, G.F, Li, X.
Deposit date:2016-05-15
Release date:2016-06-29
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure-Based Tetravalent Zanamivir with Potent Inhibitory Activity against Drug-Resistant Influenza Viruses
J.Med.Chem., 59, 2016
3S5J
DownloadVisualize
BU of 3s5j by Molmil
2.0A Crystal structure of human phosphoribosyl pyrophosphate synthetase 1
Descriptor: Ribose-phosphate pyrophosphokinase 1, SULFATE ION
Authors:Chen, P, Teng, M, Li, X.
Deposit date:2011-05-23
Release date:2012-05-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Crystal and EM Structures of Human Phosphoribosyl Pyrophosphate Synthase I (PRS1) Provide Novel Insights into the Disease-Associated Mutations
Plos One, 10, 2015
4LA1
DownloadVisualize
BU of 4la1 by Molmil
Crystal structure of SjTGR (thioredoxin glutathione reductase from Schistosoma japonicumi)complex with FAD
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Thioredoxin glutathione reductase
Authors:Peng, Y, Wu, Q, Huang, F, Chen, J, Li, X, Zhou, X, Fan, X.
Deposit date:2013-06-18
Release date:2014-07-30
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.348 Å)
Cite:Crystal structure of SjTGR complex with FAD
To be Published
7RR5
DownloadVisualize
BU of 7rr5 by Molmil
Structure of ribosomal complex bound with Rbg1/Tma46
Descriptor: 18S rRNA, 25S rRNA, 40S ribosomal protein S0, ...
Authors:Zeng, F, Li, X, Pires-Alves, M, Chen, X, Hawk, C.W, Jin, H.
Deposit date:2021-08-09
Release date:2021-11-10
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (3.23 Å)
Cite:Conserved heterodimeric GTPase Rbg1/Tma46 promotes efficient translation in eukaryotic cells.
Cell Rep, 37, 2021
5XSG
DownloadVisualize
BU of 5xsg by Molmil
Ultrahigh resolution structure of FUS (37-42) SYSGYS determined by MicroED
Descriptor: RNA-binding protein FUS
Authors:Luo, F, Gui, X, Zhou, H, Li, D, Li, X, Liu, C.
Deposit date:2017-06-14
Release date:2018-04-04
Last modified:2024-03-27
Method:ELECTRON CRYSTALLOGRAPHY (0.73 Å)
Cite:Atomic structures of FUS LC domain segments reveal bases for reversible amyloid fibril formation.
Nat. Struct. Mol. Biol., 25, 2018
4D1Q
DownloadVisualize
BU of 4d1q by Molmil
Hermes transposase bound to its terminal inverted repeat
Descriptor: SODIUM ION, TERMINAL INVERTED REPEAT, TRANSPOSASE
Authors:Hickman, A.B, Ewis, H, Li, X, Knapp, J, Laver, T, Doss, A.L, Tolun, G, Steven, A, Grishaev, A, Bax, A, Atkinson, P, Craig, N.L, Dyda, F.
Deposit date:2014-05-04
Release date:2014-07-30
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural Basis of Hat Transposon End Recognition by Hermes, an Octameric DNA Transposase from Musca Domestica.
Cell(Cambridge,Mass.), 158, 2014
4UIS
DownloadVisualize
BU of 4uis by Molmil
The cryoEM structure of human gamma-Secretase complex
Descriptor: GAMMA-SECRETASE, LYSOZYME
Authors:Sun, L, Zhao, L, Yang, G, Yan, C, Zhou, R, Zhou, X, Xie, T, Zhao, Y, Wu, S, Li, X, Shi, Y.
Deposit date:2015-04-03
Release date:2015-06-10
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structural Basis of Human Gamma-Secretase Assembly.
Proc.Natl.Acad.Sci.USA, 112, 2015
9B4E
DownloadVisualize
BU of 9b4e by Molmil
Structure of wild type human PSS1
Descriptor: (2R)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dihexadecanoate, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, CALCIUM ION, ...
Authors:Long, T, Li, X.
Deposit date:2024-03-20
Release date:2024-09-04
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Molecular insights into human phosphatidylserine synthase 1 reveal its inhibition promotes LDL uptake.
Cell, 187, 2024
9B4G
DownloadVisualize
BU of 9b4g by Molmil
Structure of inhibitor-bound human PSS1
Descriptor: (2R)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dihexadecanoate, (7P)-7-[(4S)-4-{4-[3,5-bis(trifluoromethyl)phenoxy]phenyl}-5-(2,2-difluoropropyl)-6-oxo-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl]-1,3-benzoxazol-2(3H)-one, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, ...
Authors:Long, T, Li, X.
Deposit date:2024-03-20
Release date:2024-09-04
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.87 Å)
Cite:Molecular insights into human phosphatidylserine synthase 1 reveal its inhibition promotes LDL uptake.
Cell, 187, 2024
9B4F
DownloadVisualize
BU of 9b4f by Molmil
Structure of human PSS1-P269S
Descriptor: CALCIUM ION, Phosphatidylserine synthase 1
Authors:Long, T, Li, X.
Deposit date:2024-03-20
Release date:2024-09-04
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:Molecular insights into human phosphatidylserine synthase 1 reveal its inhibition promotes LDL uptake.
Cell, 187, 2024
5XMK
DownloadVisualize
BU of 5xmk by Molmil
Cryo-EM structure of the ATP-bound Vps4 mutant-E233Q complex with Vta1 (masked)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Vacuolar protein sorting-associated protein 4, Vacuolar protein sorting-associated protein VTA1
Authors:Sun, S, Li, L, Yang, F, Wang, X, Fan, F, Li, X, Wang, H, Sui, S.
Deposit date:2017-05-15
Release date:2017-08-09
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.18 Å)
Cite:Cryo-EM structures of the ATP-bound Vps4(E233Q) hexamer and its complex with Vta1 at near-atomic resolution
Nat Commun, 8, 2017

238582

数据于2025-07-09公开中

PDB statisticsPDBj update infoContact PDBjnumon