9B4G

Structure of inhibitor-bound human PSS1

This is a non-PDB format compatible entry.

Summary for 9B4G

• Entry DOI: 10.2210/pdb9b4g/pdb
• EMDB information: 44180
• Descriptor: Phosphatidylserine synthase 1, O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, ... (8 entities in total)
• Functional Keywords: membrane protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 107342.85

Authors

Long, T.,Li, X. (deposition date: 2024-03-20, release date: 2024-09-04, Last modification date: 2024-09-11)

• Primary citation: Long, T.,Li, D.,Vale, G.,Jiang, Y.,Schmiege, P.,Yang, Z.J.,McDonald, J.G.,Li, X.; Molecular insights into human phosphatidylserine synthase 1 reveal its inhibition promotes LDL uptake.; Cell, 2024; PubMed: 39208797; DOI: 10.1016/j.cell.2024.08.004

Experimental method

ELECTRON MICROSCOPY (2.87 Å)