Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
7CWM
DownloadVisualize
BU of 7cwm by Molmil
Complex of SARS-CoV-2 spike protein and Fab P17 with one RBD in open state and two RBD in closed state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, P17 heavy chain, ...
Authors:Wang, N, Wang, X.
Deposit date:2020-08-29
Release date:2020-12-16
Last modified:2021-01-13
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection.
Cell Res., 31, 2021
7TVA
DownloadVisualize
BU of 7tva by Molmil
Stat5a Core in complex with AK2292
Descriptor: DI(HYDROXYETHYL)ETHER, MALONATE ION, N-{5-[difluoro(phosphono)methyl]-1-benzothiophene-2-carbonyl}-3-methyl-L-valyl-L-prolyl-N-(5-{2-[(3R)-2,6-dioxopiperidin-3-yl]-1-oxo-2,3-dihydro-1H-isoindol-4-yl}pent-4-yn-1-yl)-N-methyl-N~3~-[4-(1,3-thiazol-2-yl)phenyl]-beta-alaninamide, ...
Authors:Meagher, J.L, Stuckey, J.A.
Deposit date:2022-02-04
Release date:2023-02-15
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.835 Å)
Cite:A selective small-molecule STAT5 PROTAC degrader capable of achieving tumor regression in vivo.
Nat.Chem.Biol., 19, 2023
7TVB
DownloadVisualize
BU of 7tvb by Molmil
Stat5A Core in Complex with AK305
Descriptor: GLYCEROL, N-{5-[difluoro(phosphono)methyl]-1-benzothiophene-2-carbonyl}-3-methyl-L-valyl-L-prolyl-N,N-dimethyl-N~3~-[4-(1,3-thiazol-2-yl)phenyl]-beta-alaninamide, Signal transducer and activator of transcription 5A
Authors:Meagher, J.L, Stuckey, J.A.
Deposit date:2022-02-04
Release date:2023-02-15
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.653 Å)
Cite:A selective small-molecule STAT5 PROTAC degrader capable of achieving tumor regression in vivo.
Nat.Chem.Biol., 19, 2023
4O1I
DownloadVisualize
BU of 4o1i by Molmil
Crystal Structure of the regulatory domain of MtbGlnR
Descriptor: Transcriptional regulatory protein
Authors:Lin, W, Wang, C, Zhang, P.
Deposit date:2013-12-16
Release date:2014-04-23
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Atypical OmpR/PhoB Subfamily Response Regulator GlnR of Actinomycetes Functions as a Homodimer, Stabilized by the Unphosphorylated Conserved Asp-focused Charge Interactions
J.Biol.Chem., 289, 2014
4O1H
DownloadVisualize
BU of 4o1h by Molmil
Crystal Structure of the regulatory domain of AmeGlnR
Descriptor: Transcription regulator GlnR
Authors:Lin, W, Wang, C, Zhang, P.
Deposit date:2013-12-16
Release date:2014-04-23
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Atypical OmpR/PhoB Subfamily Response Regulator GlnR of Actinomycetes Functions as a Homodimer, Stabilized by the Unphosphorylated Conserved Asp-focused Charge Interactions
J.Biol.Chem., 289, 2014
6J8L
DownloadVisualize
BU of 6j8l by Molmil
Phytophthora sojae effector PsAvh240 inhibits a host aspartic protease secretion to promote infection
Descriptor: Avh240, SULFATE ION
Authors:Guo, B.
Deposit date:2019-01-19
Release date:2019-02-06
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Phytophthora sojae Effector PsAvh240 Inhibits Host Aspartic Protease Secretion to Promote Infection.
Mol Plant, 12, 2019
6IIO
DownloadVisualize
BU of 6iio by Molmil
Cryo-EM structure of CV-A10 native empty particle
Descriptor: VP0, VP1, VP3
Authors:Chen, J.H, Ye, X.H, Cong, Y, Huang, Z.
Deposit date:2018-10-07
Release date:2018-11-07
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Coxsackievirus A10 atomic structure facilitating the discovery of a broad-spectrum inhibitor against human enteroviruses.
Cell Discov, 5, 2019
7XR2
DownloadVisualize
BU of 7xr2 by Molmil
3.1 Angstrom cryoEM icosahedral reconstruction of mud crab reovirus
Descriptor: VP11, VP12, VP3
Authors:Zhang, Q, Gao, Y.
Deposit date:2022-05-09
Release date:2023-04-19
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:The structure of a 12-segmented dsRNA reovirus: New insights into capsid stabilization and organization.
Plos Pathog., 19, 2023
7XR3
DownloadVisualize
BU of 7xr3 by Molmil
3.4 Angstrom cryoEM D5 reconstruction of mud crab reovirus
Descriptor: VP1, VP3
Authors:Zhang, Q.F, Gao, Y.Z.
Deposit date:2022-05-09
Release date:2023-04-19
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:The structure of a 12-segmented dsRNA reovirus: New insights into capsid stabilization and organization.
Plos Pathog., 19, 2023
7XZO
DownloadVisualize
BU of 7xzo by Molmil
Formate-tetrahydrofolate ligase in complex with ATP
Descriptor: (R,R)-2,3-BUTANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, Formate--tetrahydrofolate ligase, ...
Authors:Fang, C.L, Zhang, Y.
Deposit date:2022-06-03
Release date:2023-06-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Identification of FtfL as a novel target of berberine in intestinal bacteria.
Bmc Biol., 21, 2023
7XZN
DownloadVisualize
BU of 7xzn by Molmil
Formate-tetrahydrofolate ligase from Peptostreptococcus anaerobius
Descriptor: 1,2-ETHANEDIOL, Formate--tetrahydrofolate ligase, TRIS(HYDROXYETHYL)AMINOMETHANE
Authors:Fang, C.L, Zhang, Y.
Deposit date:2022-06-03
Release date:2023-06-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Identification of FtfL as a novel target of berberine in intestinal bacteria.
Bmc Biol., 21, 2023
7XZP
DownloadVisualize
BU of 7xzp by Molmil
Formate-tetrahydrofolate ligase in complex with berberine
Descriptor: BERBERINE, Formate--tetrahydrofolate ligase, PROLINE, ...
Authors:Fang, C.L, Zhang, Y.
Deposit date:2022-06-03
Release date:2023-06-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Identification of FtfL as a novel target of berberine in intestinal bacteria.
Bmc Biol., 21, 2023
4ISI
DownloadVisualize
BU of 4isi by Molmil
Structure of FACTOR VIIA in complex with the inhibitor (6S)-N-(4-CARBAMIMIDOYLBENZYL)-1-CHLORO-3-(CYCLOBUTYLAMINO)-8,8-DIETHYL-4-OXO-4,6,7,8-TETRAHYDROPYRROLO[1,2-A]PYRAZINE-6-CARBOXAMIDE
Descriptor: (6S)-N-(4-carbamimidoylbenzyl)-1-chloro-3-(cyclobutylamino)-8,8-diethyl-4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-a]pyrazine-6-carboxamide, CALCIUM ION, Factor VII heavy chain, ...
Authors:Wei, A.
Deposit date:2013-01-16
Release date:2013-02-27
Last modified:2013-03-06
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Design and synthesis of bicyclic pyrazinone and pyrimidinone amides as potent TF-FVIIa inhibitors.
Bioorg.Med.Chem.Lett., 23, 2013
4KQ8
DownloadVisualize
BU of 4kq8 by Molmil
Structure of Recombinant Human Cytochrome P450 Aromatase
Descriptor: 4-ANDROSTENE-3-17-DIONE, Cytochrome P450 19A1, PHOSPHATE ION, ...
Authors:Ghosh, D, Di Nardo, G, Griswold, J.
Deposit date:2013-05-14
Release date:2013-08-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.29 Å)
Cite:Structural basis for the functional roles of critical residues in human cytochrome p450 aromatase.
Biochemistry, 52, 2013
5W3M
DownloadVisualize
BU of 5w3m by Molmil
CryoEM structure of rhinovirus B14 in complex with C5 Fab (33 degrees Celsius, molar ratio 1:1, full particle)
Descriptor: C5 antibody variable heavy domain, C5 antibody variable light domain, viral protein 1, ...
Authors:Liu, Y, Dong, Y, Rossmann, M.G.
Deposit date:2017-06-08
Release date:2017-07-12
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (2.26 Å)
Cite:Antibody-induced uncoating of human rhinovirus B14.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5VEB
DownloadVisualize
BU of 5veb by Molmil
Crystal structure of a Fab binding to extracellular domain 5 of Cadherin-6
Descriptor: 2-acetamido-2-deoxy-alpha-D-galactopyranose, Cadherin-6, anti-CDH6 Fab heavy chain, ...
Authors:Zhu, X, Bialucha, C.U, London, A, Clark, K, Hu, T.
Deposit date:2017-04-04
Release date:2017-06-07
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Discovery and Optimization of HKT288, a Cadherin-6-Targeting ADC for the Treatment of Ovarian and Renal Cancers.
Cancer Discov, 7, 2017
6IIJ
DownloadVisualize
BU of 6iij by Molmil
Cryo-EM structure of CV-A10 mature virion
Descriptor: SPHINGOSINE, VP1, VP2, ...
Authors:Chen, J.H, Ye, X.H, Cong, Y, Huang, Z.
Deposit date:2018-10-06
Release date:2018-11-07
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (2.84 Å)
Cite:Coxsackievirus A10 atomic structure facilitating the discovery of a broad-spectrum inhibitor against human enteroviruses.
Cell Discov, 5, 2019
4KVC
DownloadVisualize
BU of 4kvc by Molmil
2H2 Fab fragment of immature Dengue virus
Descriptor: Ig heavy chain V region MOPC 21, Igh protein, Ig kappa chain V-V region MOPC 21, ...
Authors:Wang, Z, Rossmann, M.G.
Deposit date:2013-05-22
Release date:2013-07-24
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2.306 Å)
Cite:Obstruction of Dengue Virus Maturation by Fab Fragments of the 2H2 Antibody.
J.Virol., 87, 2013
5U6J
DownloadVisualize
BU of 5u6j by Molmil
Factor VIIa in complex with the inhibitor 3-{[(2R)-17-ethyl-4-methyl-3,12-dioxo-7-[(propan-2-yl)sulfonyl]-13-oxa-4,11-diazatricyclo[14.2.2.1~6,10~]henicosa-1(18),6(21),7,9,16,19-hexaen-2-yl]amino}benzamide
Descriptor: 3-{[(2R)-17-ethyl-4-methyl-3,12-dioxo-7-[(propan-2-yl)sulfonyl]-13-oxa-4,11-diazatricyclo[14.2.2.1~6,10~]henicosa-1(18),6(21),7,9,16,19-hexaen-2-yl]amino}benzamide, CALCIUM ION, Coagulation factor VII Heavy Chain, ...
Authors:Wei, A.
Deposit date:2016-12-08
Release date:2017-05-10
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Neutral macrocyclic factor VIIa inhibitors.
Bioorg. Med. Chem. Lett., 27, 2017
5W3O
DownloadVisualize
BU of 5w3o by Molmil
CryoEM structure of rhinovirus B14 in complex with C5 Fab (33 degrees Celsius, molar ratio 1:3, empty particle)
Descriptor: C5 antibody variable heavy domain, C5 antibody variable light domain, viral protein 1, ...
Authors:Liu, Y, Dong, Y, Rossmann, M.G.
Deposit date:2017-06-08
Release date:2017-07-12
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.01 Å)
Cite:Antibody-induced uncoating of human rhinovirus B14.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W3L
DownloadVisualize
BU of 5w3l by Molmil
CryoEM structure of rhinovirus B14 in complex with C5 Fab (4 degrees Celsius, molar ratio 1:3, full particle)
Descriptor: C5 antibody variable heavy domain, C5 antibody variable light domain, viral protein 1, ...
Authors:Liu, Y, Dong, Y, Rossmann, M.G.
Deposit date:2017-06-08
Release date:2017-07-12
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (2.71 Å)
Cite:Antibody-induced uncoating of human rhinovirus B14.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W3E
DownloadVisualize
BU of 5w3e by Molmil
CryoEM structure of rhinovirus B14 in complex with C5 Fab (33 degrees Celsius, molar ratio 1:3, full particle)
Descriptor: C5 antibody variable heavy domain, C5 antibody variable light domain, viral protein 1, ...
Authors:Liu, Y, Dong, Y, Rossmann, M.G.
Deposit date:2017-06-07
Release date:2017-07-12
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (2.53 Å)
Cite:Antibody-induced uncoating of human rhinovirus B14.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
7E9B
DownloadVisualize
BU of 7e9b by Molmil
Structural basis of HLX10 PD-1 receptor recognition, a promising anti-PD-1 antibody clinical candidate for cancer immunotherapy
Descriptor: Programmed cell death protein 1, heavy chain of Fab fragment of HLX10, light chain of Fab fragment of HLX10
Authors:Fan, S.L, Jiang, W.D.
Deposit date:2021-03-04
Release date:2021-07-28
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structural basis of HLX10 PD-1 receptor recognition, a promising anti-PD-1 antibody clinical candidate for cancer immunotherapy.
Plos One, 16, 2021
4PLI
DownloadVisualize
BU of 4pli by Molmil
Structure of the chromodomain of MRG2 in complex with H3K36me3
Descriptor: At1g02740, H3K36me3
Authors:Liu, Y, Huang, Y.
Deposit date:2014-05-18
Release date:2015-07-22
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.651 Å)
Cite:Regulation of arabidopsis flowering by the histone mark readers MRG1/2 via interaction with CONSTANS to modulate FT expression.
Plos Genet., 10, 2014
4PL6
DownloadVisualize
BU of 4pl6 by Molmil
Structure of the chromodomain of MRG2 in complex with H3K4me3
Descriptor: At1g02740, H3K4me3
Authors:Liu, Y.C, Huang, Y.
Deposit date:2014-05-16
Release date:2015-07-22
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.681 Å)
Cite:Regulation of arabidopsis flowering by the histone mark readers MRG1/2 via interaction with CONSTANS to modulate FT expression.
Plos Genet., 10, 2014

226707

数据于2024-10-30公开中

PDB statisticsPDBj update infoContact PDBjnumon