6DMZ
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![BU of 6dmz by Molmil](/molmil-images/mine/6dmz) | Solution structure of ZmD32 | Descriptor: | Flower-specific gamma-thionin | Authors: | Harvey, P.J, Craik, D.J. | Deposit date: | 2018-06-05 | Release date: | 2019-05-15 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Salt-Tolerant Antifungal and Antibacterial Activities of the Corn Defensin ZmD32. Front Microbiol, 10, 2019
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3IEG
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![BU of 3ieg by Molmil](/molmil-images/mine/3ieg) | Crystal Structure of P58(IPK) TPR Domain at 2.5 A | Descriptor: | DnaJ homolog subfamily C member 3 | Authors: | Tao, J, Sha, B. | Deposit date: | 2009-07-22 | Release date: | 2010-03-31 | Last modified: | 2019-07-24 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Crystal Structure of P58(IPK) TPR Fragment Reveals the Mechanism for its Molecular Chaperone Activity in UPR. J.Mol.Biol., 64, 2010
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7QL7
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![BU of 7ql7 by Molmil](/molmil-images/mine/7ql7) | Crystal structure of YTHDF1 YTH domain in complex with the ebsulfur derivative compound 9 | Descriptor: | 1,2-ETHANEDIOL, THIOCYANATE ION, YTH domain-containing family protein 1, ... | Authors: | Dalle Vedove, A, Cazzanelli, G, Quattrone, A, Provenzani, A, Lolli, G. | Deposit date: | 2021-12-19 | Release date: | 2022-11-23 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Small-Molecule Ebselen Binds to YTHDF Proteins Interfering with the Recognition of N 6 -Methyladenosine-Modified RNAs. Acs Pharmacol Transl Sci, 5, 2022
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1QQL
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![BU of 1qql by Molmil](/molmil-images/mine/1qql) | THE CRYSTAL STRUCTURE OF FIBROBLAST GROWTH FACTOR 7/1 CHIMERA | Descriptor: | FIBROBLAST GROWTH FACTOR 7/1 CHIMERA | Authors: | Ye, S, Luo, Y, Pelletier, H, McKeehan, W.L. | Deposit date: | 1999-06-07 | Release date: | 2000-01-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for interaction of FGF-1, FGF-2, and FGF-7 with different heparan sulfate motifs. Biochemistry, 40, 2001
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1QQK
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![BU of 1qqk by Molmil](/molmil-images/mine/1qqk) | THE CRYSTAL STRUCTURE OF FIBROBLAST GROWTH FACTOR 7 (KERATINOCYTE GROWTH FACTOR) | Descriptor: | FIBROBLAST GROWTH FACTOR 7 | Authors: | Ye, S, Luo, Y, Pelletier, H, McKeehan, W.L. | Deposit date: | 1999-06-07 | Release date: | 2000-01-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural basis for interaction of FGF-1, FGF-2, and FGF-7 with different heparan sulfate motifs. Biochemistry, 40, 2001
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7ME0
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![BU of 7me0 by Molmil](/molmil-images/mine/7me0) | Cryo-EM structure of SARS-CoV-2 NSP15 NendoU at pH 6.0 | Descriptor: | Uridylate-specific endoribonuclease | Authors: | Godoy, A.S, Song, Y, Nakamura, A.M, Noske, G.D, Gawriljuk, V.O, Fernandes, R.S, Oliva, G. | Deposit date: | 2021-04-06 | Release date: | 2021-04-14 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.48 Å) | Cite: | Allosteric regulation and crystallographic fragment screening of SARS-CoV-2 NSP15 endoribonuclease. Nucleic Acids Res., 2023
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3LJ1
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![BU of 3lj1 by Molmil](/molmil-images/mine/3lj1) | IRE1 complexed with Cdk1/2 Inhibitor III | Descriptor: | 5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE, Serine/threonine-protein kinase/endoribonuclease IRE1 | Authors: | Lee, K.P.K, Sicheri, F. | Deposit date: | 2010-01-25 | Release date: | 2010-05-12 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.33 Å) | Cite: | Flavonol activation defines an unanticipated ligand-binding site in the kinase-RNase domain of IRE1. Mol.Cell, 38, 2010
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7RB0
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![BU of 7rb0 by Molmil](/molmil-images/mine/7rb0) | Cryo-EM structure of SARS-CoV-2 NSP15 NendoU at pH 7.5 | Descriptor: | Uridylate-specific endoribonuclease | Authors: | Godoy, A.S, Song, Y, Nakamura, A.M, Noske, G.D, Gawriljuk, V.O, Fernandes, R.S, Oliva, G. | Deposit date: | 2021-07-05 | Release date: | 2021-07-14 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.98 Å) | Cite: | Allosteric regulation and crystallographic fragment screening of SARS-CoV-2 NSP15 endoribonuclease. Nucleic Acids Res., 51, 2023
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7RB2
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![BU of 7rb2 by Molmil](/molmil-images/mine/7rb2) | Cryo-EM structure of SARS-CoV-2 NSP15 NendoU in BIS-Tris pH 6.0 | Descriptor: | Uridylate-specific endoribonuclease | Authors: | Godoy, A.S, Song, Y, Nakamura, A.M, Noske, G.D, Gawriljuk, V.O, Fernandes, R.S, Oliva, G. | Deposit date: | 2021-07-05 | Release date: | 2021-07-14 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.27 Å) | Cite: | Allosteric regulation and crystallographic fragment screening of SARS-CoV-2 NSP15 endoribonuclease. Nucleic Acids Res., 51, 2023
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3LJ0
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![BU of 3lj0 by Molmil](/molmil-images/mine/3lj0) | IRE1 complexed with ADP and Quercetin | Descriptor: | 3,5,7,3',4'-PENTAHYDROXYFLAVONE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Lee, K.P.K, Sicheri, F. | Deposit date: | 2010-01-25 | Release date: | 2010-05-12 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Flavonol activation defines an unanticipated ligand-binding site in the kinase-RNase domain of IRE1. Mol.Cell, 38, 2010
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3QD2
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![BU of 3qd2 by Molmil](/molmil-images/mine/3qd2) | Crystal structure of mouse PERK kinase domain | Descriptor: | Eukaryotic translation initiation factor 2-alpha kinase 3 | Authors: | Wenjun, C, Jingzhi, L, David, R, Bingdong, S. | Deposit date: | 2011-01-17 | Release date: | 2011-04-27 | Last modified: | 2019-01-16 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | The structure of the PERK kinase domain suggests the mechanism for its activation. Acta Crystallogr.,Sect.D, 67, 2011
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3LJ2
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![BU of 3lj2 by Molmil](/molmil-images/mine/3lj2) | IRE1 complexed with JAK Inhibitor I | Descriptor: | 2-TERT-BUTYL-9-FLUORO-3,6-DIHYDRO-7H-BENZ[H]-IMIDAZ[4,5-F]ISOQUINOLINE-7-ONE, Serine/threonine-protein kinase/endoribonuclease IRE1 | Authors: | Lee, K.P.K, Sicheri, F. | Deposit date: | 2010-01-25 | Release date: | 2010-05-12 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.33 Å) | Cite: | Flavonol activation defines an unanticipated ligand-binding site in the kinase-RNase domain of IRE1. Mol.Cell, 38, 2010
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8GLB
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![BU of 8glb by Molmil](/molmil-images/mine/8glb) | Selenomethionine Derivatized Citrate Synthase (CitA) in Mycobacterium tuberculosis with Pyruvate | Descriptor: | 1,2-ETHANEDIOL, PYRUVIC ACID, citrate synthase | Authors: | Pathirage, R, Ronning, D, Favrot, L. | Deposit date: | 2023-03-21 | Release date: | 2023-06-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding. Rsc Med Chem, 14, 2023
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8GMI
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![BU of 8gmi by Molmil](/molmil-images/mine/8gmi) | |
8GI7
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![BU of 8gi7 by Molmil](/molmil-images/mine/8gi7) | |
8GM9
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![BU of 8gm9 by Molmil](/molmil-images/mine/8gm9) | Structure of Citrate Synthase(CitA) in Mycobacterium Tuberculosis | Descriptor: | 1,2-ETHANEDIOL, ACRYLIC ACID, DI(HYDROXYETHYL)ETHER, ... | Authors: | Pathirage, R, Ronning, D, Favrot, L. | Deposit date: | 2023-03-24 | Release date: | 2023-06-07 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding. Rsc Med Chem, 14, 2023
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8GLL
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![BU of 8gll by Molmil](/molmil-images/mine/8gll) | R149E variant of Citrate Synthase (CitA) in Mycobacterium tuberculosis | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, SULFATE ION, ... | Authors: | Pathirage, R, Ronning, D, Petit, C. | Deposit date: | 2023-03-22 | Release date: | 2023-06-07 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding. Rsc Med Chem, 14, 2023
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8GMK
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![BU of 8gmk by Molmil](/molmil-images/mine/8gmk) | Pyruvate bound structure of Citrate Synthase (CitA) in Mycobacterium Tuberculosis | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, PYRUVIC ACID, ... | Authors: | Pathirage, R, Ronning, D, Yamsek, M. | Deposit date: | 2023-03-26 | Release date: | 2023-06-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding. Rsc Med Chem, 14, 2023
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8GMF
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![BU of 8gmf by Molmil](/molmil-images/mine/8gmf) | |
8GIW
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![BU of 8giw by Molmil](/molmil-images/mine/8giw) | |
7D45
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![BU of 7d45 by Molmil](/molmil-images/mine/7d45) | eIF2B-eIF2(aP), aP1 complex | Descriptor: | Eukaryotic translation initiation factor 2 subunit 1, Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, ... | Authors: | Kashiwagi, K, Ito, T. | Deposit date: | 2020-09-22 | Release date: | 2020-12-09 | Last modified: | 2021-01-27 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | ISRIB Blunts the Integrated Stress Response by Allosterically Antagonising the Inhibitory Effect of Phosphorylated eIF2 on eIF2B. Mol.Cell, 81, 2021
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7D44
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![BU of 7d44 by Molmil](/molmil-images/mine/7d44) | eIF2B-eIF2(aP), aP2 complex | Descriptor: | Eukaryotic translation initiation factor 2 subunit 1, Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, ... | Authors: | Kashiwagi, K, Ito, T. | Deposit date: | 2020-09-22 | Release date: | 2020-12-09 | Last modified: | 2021-01-27 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | ISRIB Blunts the Integrated Stress Response by Allosterically Antagonising the Inhibitory Effect of Phosphorylated eIF2 on eIF2B. Mol.Cell, 81, 2021
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7D46
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![BU of 7d46 by Molmil](/molmil-images/mine/7d46) | eIF2B apo | Descriptor: | Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit delta, ... | Authors: | Kashiwagi, K, Ito, T. | Deposit date: | 2020-09-22 | Release date: | 2020-12-09 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | ISRIB Blunts the Integrated Stress Response by Allosterically Antagonising the Inhibitory Effect of Phosphorylated eIF2 on eIF2B. Mol.Cell, 81, 2021
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7D43
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![BU of 7d43 by Molmil](/molmil-images/mine/7d43) | eIF2B-eIF2(aP), aPg complex | Descriptor: | Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 2, Eukaryotic translation initiation factor 2 subunit 3, ... | Authors: | Kashiwagi, K, Ito, T. | Deposit date: | 2020-09-22 | Release date: | 2020-12-09 | Last modified: | 2021-01-27 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | ISRIB Blunts the Integrated Stress Response by Allosterically Antagonising the Inhibitory Effect of Phosphorylated eIF2 on eIF2B. Mol.Cell, 81, 2021
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8S9D
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![BU of 8s9d by Molmil](/molmil-images/mine/8s9d) | |