7RB2

Cryo-EM structure of SARS-CoV-2 NSP15 NendoU in BIS-Tris pH 6.0

Summary for 7RB2

• Entry DOI: 10.2210/pdb7rb2/pdb
• EMDB information: 24392
• Descriptor: Uridylate-specific endoribonuclease (1 entity in total)
• Functional Keywords: nsp15, sars-cov-2, nendou, coronavirus, covid-19, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2, COVID-19 virus)
• Total number of polymer chains: 6
• Total formula weight: 234675.21

Authors

Godoy, A.S.,Song, Y.,Nakamura, A.M.,Noske, G.D.,Gawriljuk, V.O.,Fernandes, R.S.,Oliva, G. (deposition date: 2021-07-05, release date: 2021-07-14, Last modification date: 2023-06-21)

• Primary citation: Godoy, A.S.,Nakamura, A.M.,Douangamath, A.,Song, Y.,Noske, G.D.,Gawriljuk, V.O.,Fernandes, R.S.,Pereira, H.D.M.,Oliveira, K.I.Z.,Fearon, D.,Dias, A.,Krojer, T.,Fairhead, M.,Powell, A.,Dunnet, L.,Brandao-Neto, J.,Skyner, R.,Chalk, R.,Bajusz, D.,Bege, M.,Borbas, A.,Keseru, G.M.,von Delft, F.,Oliva, G.; Allosteric regulation and crystallographic fragment screening of SARS-CoV-2 NSP15 endoribonuclease.; Nucleic Acids Res., 51:5255-5270, 2023; PubMed: 37115000; DOI: 10.1093/nar/gkad314

Experimental method

ELECTRON MICROSCOPY (3.27 Å)