7ME0
Cryo-EM structure of SARS-CoV-2 NSP15 NendoU at pH 6.0
Summary for 7ME0
Entry DOI | 10.2210/pdb7me0/pdb |
EMDB information | 23786 |
Descriptor | Uridylate-specific endoribonuclease (1 entity in total) |
Functional Keywords | nsp15, sars-cov-2, nendou, coronavirus, covid-19, viral protein, hydrolase |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2) |
Total number of polymer chains | 6 |
Total formula weight | 252707.06 |
Authors | Godoy, A.S.,Song, Y.,Nakamura, A.M.,Noske, G.D.,Gawriljuk, V.O.,Fernandes, R.S.,Oliva, G. (deposition date: 2021-04-06, release date: 2021-04-14, Last modification date: 2024-05-29) |
Primary citation | Godoy, A.S.,Nakamura, A.M.,Douangamath, A.,Song, Y.,Noske, G.D.,Gawriljuk, V.O.,Fernandes, R.S.,Pereira, H.D.M.,Oliveira, K.I.Z.,Fearon, D.,Dias, A.,Krojer, T.,Fairhead, M.,Powell, A.,Dunnet, L.,Brandao-Neto, J.,Skyner, R.,Chalk, R.,Bajusz, D.,Bege, M.,Borbas, A.,Keseru, G.M.,von Delft, F.,Oliva, G. Allosteric regulation and crystallographic fragment screening of SARS-CoV-2 NSP15 endoribonuclease. Nucleic Acids Res., 2023 Cited by PubMed: 37115000DOI: 10.1093/nar/gkad314 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.48 Å) |
Structure validation
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