7ME0

Cryo-EM structure of SARS-CoV-2 NSP15 NendoU at pH 6.0

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Uridylate-specific endoribonuclease	polymer	373	42117.8	6	UniProt (P0DTD1) Pfam (PF19219) Pfam (PF19216) Pfam (PF19215) In PDB	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2)	NendoU,Non-structural protein 15,nsp15

Sequence modifications

A, B, C, D, E, F: 1 - 346 (UniProt: P0DTD1)

PDB	External Database	Details
Met -26	-	initiating methionine
Lys -25	-	expression tag
His -24	-	expression tag
His -23	-	expression tag
His -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
Pro -18	-	expression tag
Met -17	-	expression tag
Ser -16	-	expression tag
Asp -15	-	expression tag
Tyr -14	-	expression tag
Asp -13	-	expression tag
Ile -12	-	expression tag
Pro -11	-	expression tag
Thr -10	-	expression tag
Thr -9	-	expression tag
Glu -8	-	expression tag
Asn -7	-	expression tag
Leu -6	-	expression tag
Tyr -5	-	expression tag
Phe -4	-	expression tag
Gln -3	-	expression tag
Gly -2	-	expression tag
Ala -1	-	expression tag
Met 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	252707.1
All*	Total formula weight	252707.1

*Water molecules are not included.