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4MM7
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BU of 4mm7 by Molmil
Crystal structure of LeuBAT (delta13 mutant) in complex with desvenlafaxine
Descriptor: 4-[(1R)-2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol, SODIUM ION, Transporter
Authors:Wang, H, Gouaux, E.
Deposit date:2013-09-08
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural basis for action by diverse antidepressants on biogenic amine transporters.
Nature, 503, 2013
4MMC
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BU of 4mmc by Molmil
Crystal structure of LeuBAT (delta6 mutant) in complex with desvenlafaxine
Descriptor: 4-[(1R)-2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol, SODIUM ION, Transporter, ...
Authors:Wang, H, Gouaux, E.
Deposit date:2013-09-08
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for action by diverse antidepressants on biogenic amine transporters.
Nature, 503, 2013
4MM6
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BU of 4mm6 by Molmil
Crystal structure of LeuBAT (delta13 mutant) in complex with (S)-duloxetine
Descriptor: (3S)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine, SODIUM ION, Transporter
Authors:Wang, H, Gouaux, E.
Deposit date:2013-09-08
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for action by diverse antidepressants on biogenic amine transporters.
Nature, 503, 2013
4MME
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BU of 4mme by Molmil
Crystal structure of LeuBAT (delta6 mutant) in complex with mazindol
Descriptor: (5R)-5-(4-chlorophenyl)-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-ol, SODIUM ION, Transporter, ...
Authors:Wang, H, Gouaux, E.
Deposit date:2013-09-08
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for action by diverse antidepressants on biogenic amine transporters.
Nature, 503, 2013
2YW8
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BU of 2yw8 by Molmil
Crystal structure of human RUN and FYVE domain-containing protein
Descriptor: RUN and FYVE domain-containing protein 1, SULFATE ION, ZINC ION
Authors:Wang, H, Kishishita, S, Murayama, K, Takemoto, C, Terada, T, Shirouzu, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-20
Release date:2008-04-22
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of human RUN and FYVE domain-containing protein
To be Published
2YV6
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BU of 2yv6 by Molmil
Crystal structure of human Bcl-2 family protein Bak
Descriptor: Bcl-2 homologous antagonist/killer, SULFATE ION
Authors:Wang, H, Kishishita, S, Murayama, K, Takemoto, C, Terada, T, Shirouzu, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-09
Release date:2008-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Novel dimerization mode of the human Bcl-2 family protein Bak, a mitochondrial apoptosis regulator.
J.Struct.Biol., 166, 2009
8R0G
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BU of 8r0g by Molmil
Capsid structure of Giardiavirus (GLV) CAT strain
Descriptor: Capsid protein
Authors:Wang, H, Gianluca, M, Munke, A, Hassan, M.M, Lalle, M, Okamoto, K.
Deposit date:2023-10-31
Release date:2024-04-03
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Capsid structure of Giardiavirus (GLV) CAT strain
To Be Published
1CGM
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BU of 1cgm by Molmil
STRUCTURE DETERMINATION OF CUCUMBER GREEN MOTTLE MOSAIC VIRUS BY X-RAY FIBER DIFFRACTION. SIGNIFICANCE FOR THE EVOLUTION OF TOBAMOVIRUSES
Descriptor: CUCUMBER GREEN MOTTLE MOSAIC VIRUS, RNA (5'-R(P*GP*AP*A)-3')
Authors:Wang, H, Stubbs, G.
Deposit date:1993-11-17
Release date:1994-04-30
Last modified:2017-11-29
Method:FIBER DIFFRACTION (3.4 Å)
Cite:Structure determination of cucumber green mottle mosaic virus by X-ray fiber diffraction. Significance for the evolution of tobamoviruses.
J.Mol.Biol., 239, 1994
8R0F
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BU of 8r0f by Molmil
Capsid structure of Giardiavirus (GLV) HP strain
Descriptor: Capsid protein
Authors:Wang, H, Gianluca, M, Munke, A, Hassan, M.M, Lalle, M, Okamoto, K.
Deposit date:2023-10-31
Release date:2024-04-03
Method:ELECTRON MICROSCOPY (2.14 Å)
Cite:Capsid structure of Giardiavirus (GLV) HP strain
To Be Published
4FXZ
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BU of 4fxz by Molmil
Crystal structure of LeuT-F253A bound to L-leucine from lipid bicelles
Descriptor: ACETATE ION, LEUCINE, SODIUM ION, ...
Authors:Wang, H, Gouaux, E.
Deposit date:2012-07-03
Release date:2012-08-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Substrate binds in the S1 site of the F253A mutant of LeuT, a neurotransmitter sodium symporter homologue.
Embo Rep., 13, 2012
4GAZ
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BU of 4gaz by Molmil
Crystal Structure of a Jumonji Domain-containing Protein JMJD5
Descriptor: Lysine-specific demethylase 8, N-OXALYLGLYCINE, NICKEL (II) ION
Authors:Wang, H, Zhou, X, Zhang, X, Tao, Y, Chen, N, Zang, J.
Deposit date:2012-07-26
Release date:2013-08-14
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Crystal Structure of a Jumonji Domain-containing Protein JMJD5
To be Published
4FY0
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BU of 4fy0 by Molmil
Crystal structure of LeuT-F253A bound to L-selenomethionine from lipid bicelles
Descriptor: SELENOMETHIONINE, SODIUM ION, Transporter
Authors:Wang, H, Gouaux, E.
Deposit date:2012-07-03
Release date:2012-08-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3 Å)
Cite:Substrate binds in the S1 site of the F253A mutant of LeuT, a neurotransmitter sodium symporter homologue.
Embo Rep., 13, 2012
4RGW
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BU of 4rgw by Molmil
Crystal Structure of a TAF1-TAF7 Complex in Human Transcription Factor IID
Descriptor: GLYCEROL, Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 7
Authors:Wang, H, Curran, E.C, Hinds, T.R, Wang, E.H, Zheng, N.
Deposit date:2014-09-30
Release date:2014-12-03
Last modified:2014-12-17
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Crystal structure of a TAF1-TAF7 complex in human transcription factor IID reveals a promoter binding module.
Cell Res., 24, 2014
3Q3J
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BU of 3q3j by Molmil
Crystal structure of plexin A2 RBD in complex with Rnd1
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Plexin-A2, ...
Authors:Wang, H, Tempel, W, Tong, Y, Guan, X, Shen, L, Buren, L, Zhang, N, Wernimont, A.K, Crombet, L, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Park, H, Structural Genomics Consortium (SGC)
Deposit date:2010-12-21
Release date:2011-01-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.971 Å)
Cite:Crystal structure of plexin A2 RBD in complex with Rnd1
to be published
3PFN
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BU of 3pfn by Molmil
Crystal Structure of human NAD kinase
Descriptor: NAD kinase, UNKNOWN ATOM OR ION
Authors:Wang, H, Tempel, W, Wernimont, A.K, Tong, Y, Guan, X, Shen, Y, Li, Y, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Park, H, Structural Genomics Consortium (SGC)
Deposit date:2010-10-28
Release date:2010-11-10
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of human NAD kinase
to be published
6KA0
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BU of 6ka0 by Molmil
Silver-bound E.coli Malate dehydrogenase
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Malate dehydrogenase, SILVER ION
Authors:Wang, H, Wang, M, Sun, H.
Deposit date:2019-06-19
Release date:2020-06-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:MDH is a major silver target in E. coli
To Be Published
5ZM8
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BU of 5zm8 by Molmil
Crystal structure of ORP2-ORD in complex with PI(4,5)P2
Descriptor: Oxysterol-binding protein-related protein 2, [(2~{S})-1-octadecanoyloxy-3-[oxidanyl-[(1~{R},2~{R},3~{S},4~{S},5~{S},6~{S})-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propan-2-yl] icosa-5,8,11,14-tetraenoate
Authors:Wang, H, Dong, J.Q, Wang, J, Wu, J.W.
Deposit date:2018-04-01
Release date:2019-01-02
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:ORP2 Delivers Cholesterol to the Plasma Membrane in Exchange for Phosphatidylinositol 4, 5-Bisphosphate (PI(4,5)P2).
Mol. Cell, 73, 2019
6KA1
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BU of 6ka1 by Molmil
E.coli Malate dehydrogenase
Descriptor: Malate dehydrogenase
Authors:Wang, H, Wang, M, Sun, H.
Deposit date:2019-06-19
Release date:2020-06-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.543 Å)
Cite:MDH is a major silver target in E. coli
To Be Published
5IZ5
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BU of 5iz5 by Molmil
Human GIVD cytosolic phospholipase A2
Descriptor: Cytosolic phospholipase A2 delta, SULFATE ION
Authors:Wang, H, Klein, M.G.
Deposit date:2016-03-24
Release date:2016-06-08
Last modified:2016-06-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of Human GIVD Cytosolic Phospholipase A2 Reveals Insights into Substrate Recognition.
J.Mol.Biol., 428, 2016
5IZR
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BU of 5izr by Molmil
Human GIVD cytosolic phospholipase A2 in complex with Methyl gamma-Linolenyl Fluorophosphonate inhibitor and Terbium Chloride
Descriptor: Cytosolic phospholipase A2 delta, TERBIUM(III) ION, methyl (R)-(6Z,9Z,12Z)-octadeca-6,9,12-trien-1-ylphosphonofluoridate
Authors:Wang, H, Klein, M.G.
Deposit date:2016-03-25
Release date:2016-06-08
Last modified:2016-06-22
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structure of Human GIVD Cytosolic Phospholipase A2 Reveals Insights into Substrate Recognition.
J.Mol.Biol., 428, 2016
2PW3
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BU of 2pw3 by Molmil
Structure of the PDE4D-cAMP complex
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, ZINC ION, cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Authors:Wang, H, Robinson, H, Ke, H.
Deposit date:2007-05-10
Release date:2007-10-23
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:The molecular basis for different recognition of substrates by phosphodiesterase families 4 and 10.
J.Mol.Biol., 371, 2007
2H40
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BU of 2h40 by Molmil
Crystal structure of the catalytic domain of unliganded PDE5
Descriptor: MAGNESIUM ION, ZINC ION, cGMP-specific 3',5'-cyclic phosphodiesterase
Authors:Wang, H, Liu, Y, Huai, Q, Cai, J, Zoraghi, R, Francis, S.H, Corbin, J.D, Robinson, H, Xin, Z, Lin, G, Ke, H.
Deposit date:2006-05-23
Release date:2006-06-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Multiple Conformations of Phosphodiesterase-5: Implications for enzyme function and drug development
J.Biol.Chem., 281, 2006
8H1K
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BU of 8h1k by Molmil
Crystal structure of glucose-2-epimerase from Runella slithyformis Runsl_4512
Descriptor: FORMIC ACID, GLYCEROL, N-acylglucosamine 2-epimerase
Authors:Wang, H, Sun, X.M, Saburi, W, Yu, J, Yao, M.
Deposit date:2022-10-03
Release date:2023-07-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural insights into the substrate specificity and activity of a novel mannose 2-epimerase from Runella slithyformis.
Acta Crystallogr D Struct Biol, 79, 2023
8H1M
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BU of 8h1m by Molmil
Crystal structure of glucose-2-epimerase mutant_D254A from Runella slithyformis Runsl_4512
Descriptor: FORMIC ACID, N-acylglucosamine 2-epimerase
Authors:Wang, H, Sun, X.M, Saburi, W, Yu, J, Yao, M.
Deposit date:2022-10-03
Release date:2023-07-12
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural insights into the substrate specificity and activity of a novel mannose 2-epimerase from Runella slithyformis.
Acta Crystallogr D Struct Biol, 79, 2023
8H1N
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BU of 8h1n by Molmil
Crystal structure of glucose-2-epimerase mutant_D254A in complex with D-Glucitol from Runella slithyformis Runsl_4512
Descriptor: FORMIC ACID, N-acylglucosamine 2-epimerase, sorbitol
Authors:Wang, H, Sun, X.M, Saburi, W, Yu, J, Yao, M.
Deposit date:2022-10-03
Release date:2023-07-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Structural insights into the substrate specificity and activity of a novel mannose 2-epimerase from Runella slithyformis.
Acta Crystallogr D Struct Biol, 79, 2023

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数据于2024-06-12公开中

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