6LNY
The co-crystal structure of Severe Acute Respiratory Syndrome Coronavirus 3C-Like Protease with aldehyde M15
Summary for 6LNY
Entry DOI | 10.2210/pdb6lny/pdb |
Descriptor | Replicase polyprotein 1a, (2~{S})-4-methyl-~{N}-[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepiperidin-3-yl]propan-2-yl]-2-[[(~{E})-3-phenylprop-2-enoyl]amino]pentanamide (3 entities in total) |
Functional Keywords | severe acute respiratory syndrome coronavirus, 3c like protease, hydrolase |
Biological source | Human SARS coronavirus (SARS-CoV) |
Total number of polymer chains | 1 |
Total formula weight | 34290.15 |
Authors | Wang, H.,Shang, L.Q. (deposition date: 2020-01-02, release date: 2020-05-27, Last modification date: 2023-11-29) |
Primary citation | Wang, H.,He, S.,Deng, W.,Zhang, Y.,Li, G.,Sun, J.,Zhao, W.,Guo, Y.,Yin, Z.,Li, D.,Shang, L. Comprehensive Insights into the Catalytic Mechanism of Middle East Respiratory Syndrome 3C-Like Protease and Severe Acute Respiratory Syndrome 3C-Like Protease. Acs Catalysis, 10:5871-5890, 2020 Cited by PubMed: 32391184DOI: 10.1021/acscatal.0c00110 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.245 Å) |
Structure validation
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