6BYF
Crystal structure of the core catalytic domain of PP-IP phosphatase SIW14 from S. cerevisiae in complex with citrate
Summary for 6BYF
Entry DOI | 10.2210/pdb6byf/pdb |
Descriptor | Tyrosine-protein phosphatase SIW14, CITRIC ACID, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | protein tyrosine phosphatase, phosphatase, inositol, inositol polyphosphate, inositol pyrophosphate, substrate specificity, transferase |
Biological source | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Cellular location | Cytoplasm : P53965 |
Total number of polymer chains | 9 |
Total formula weight | 181406.55 |
Authors | Wang, H.,Shears, S.B. (deposition date: 2017-12-20, release date: 2018-03-21, Last modification date: 2022-03-16) |
Primary citation | Wang, H.,Gu, C.,Rolfes, R.J.,Jessen, H.J.,Shears, S.B. Structural and biochemical characterization of Siw14: A protein-tyrosine phosphatase fold that metabolizes inositol pyrophosphates. J. Biol. Chem., 293:6905-6914, 2018 Cited by PubMed: 29540476DOI: 10.1074/jbc.RA117.001670 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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