7F11
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![BU of 7f11 by Molmil](/molmil-images/mine/7f11) | Crystal structure of NsrQ M128I in complex with substrate analogue 7 | Descriptor: | NsrQ, methyl 2-[2,6-bis(oxidanyl)phenyl]carbonyl-5-methyl-3,6-bis(oxidanyl)benzoate | Authors: | Yang, J, Mori, T, Abe, I. | Deposit date: | 2021-06-07 | Release date: | 2022-04-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural Basis for Isomerization Reactions in Fungal Tetrahydroxanthone Biosynthesis and Diversification. Angew.Chem.Int.Ed.Engl., 60, 2021
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7F14
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7F0Z
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![BU of 7f0z by Molmil](/molmil-images/mine/7f0z) | Crystal structure of NsrQ W31A | Descriptor: | NsrQ | Authors: | Yang, J, Mori, T, Abe, I. | Deposit date: | 2021-06-07 | Release date: | 2022-04-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Basis for Isomerization Reactions in Fungal Tetrahydroxanthone Biosynthesis and Diversification. Angew.Chem.Int.Ed.Engl., 60, 2021
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7F0O
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7F10
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7E5C
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![BU of 7e5c by Molmil](/molmil-images/mine/7e5c) | Bacterial prolidase mutant D45W/L225Y/H226L/H343I | Descriptor: | MANGANESE (II) ION, Xaa-Pro dipeptidase | Authors: | Yang, J. | Deposit date: | 2021-02-18 | Release date: | 2021-03-03 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Structure-based redesign of the bacterial prolidase active-site pocket for efficient enhancement of methyl-parathion hydrolysis Catalysis Science And Technology, 11, 2021
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7FGZ
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![BU of 7fgz by Molmil](/molmil-images/mine/7fgz) | Marine bacterial GH16 hydrolase | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, GH16 hydrolase | Authors: | Yang, J. | Deposit date: | 2021-07-28 | Release date: | 2022-08-03 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Marine bacterial GH16 hydrolase To Be Published
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8SSU
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![BU of 8ssu by Molmil](/molmil-images/mine/8ssu) | ZnFs 3-11 of CCCTC-binding factor (CTCF) Complexed with 19mer DNA | Descriptor: | 1,2-ETHANEDIOL, DNA (19-MER) Strand I, DNA (19-MER) Strand II, ... | Authors: | Horton, J.R, Yang, J, Cheng, X. | Deposit date: | 2023-05-08 | Release date: | 2023-08-02 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.89 Å) | Cite: | Structures of CTCF-DNA complexes including all 11 zinc fingers. Nucleic Acids Res., 51, 2023
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7N1R
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![BU of 7n1r by Molmil](/molmil-images/mine/7n1r) | A novel and unique ATP hydrolysis to AMP by a human Hsp70 BiP | Descriptor: | ADENOSINE MONOPHOSPHATE, DI(HYDROXYETHYL)ETHER, Endoplasmic reticulum chaperone BiP, ... | Authors: | Yang, J, Musayev, F, Liu, Q. | Deposit date: | 2021-05-28 | Release date: | 2022-01-12 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | A novel and unique ATP hydrolysis to AMP by a human Hsp70 Binding immunoglobin protein (BiP). Protein Sci., 31, 2022
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2V0P
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![BU of 2v0p by Molmil](/molmil-images/mine/2v0p) | The Structure of Tap42 Alpha4 Subunit | Descriptor: | TYPE 2A PHOSPHATASE-ASSOCIATED PROTEIN 42, ZINC ION | Authors: | Roe, S.M, Yang, J, Barford, D. | Deposit date: | 2007-05-15 | Release date: | 2007-07-17 | Last modified: | 2019-05-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The Structure of Tap42/Alpha4 Reveals a Tetratricopeptide Repeat-Like Fold and Provides Insights Into Pp2A Regulation. Biochemistry, 46, 2007
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6OD5
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![BU of 6od5 by Molmil](/molmil-images/mine/6od5) | Human TCF4 C-terminal bHLH domain in Complex with 12-bp Oligonucleotide Containing E-box Sequence with 5-carboxylcytosines | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, DNA (5'-D(*AP*(1CC)P*GP*CP*AP*CP*GP*TP*GP*(1CC)P*G)-3'), ... | Authors: | Horton, J.R, Cheng, X, Yang, J. | Deposit date: | 2019-03-25 | Release date: | 2019-05-29 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural basis for preferential binding of human TCF4 to DNA containing 5-carboxylcytosine. Nucleic Acids Res., 47, 2019
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6OD3
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![BU of 6od3 by Molmil](/molmil-images/mine/6od3) | Human TCF4 C-terminal bHLH domain in Complex with 13-bp Oligonucleotide Containing E-box Sequence | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, DNA (5'-D(*CP*AP*TP*AP*CP*AP*CP*GP*TP*GP*TP*AP*T)-3'), ... | Authors: | Horton, J.R, Cheng, X, Yang, J. | Deposit date: | 2019-03-25 | Release date: | 2019-05-29 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.494 Å) | Cite: | Structural basis for preferential binding of human TCF4 to DNA containing 5-carboxylcytosine. Nucleic Acids Res., 47, 2019
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6OD4
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![BU of 6od4 by Molmil](/molmil-images/mine/6od4) | Human TCF4 C-terminal bHLH domain in Complex with 11-bp Oligonucleotide Containing E-box Sequence | Descriptor: | 1,2-ETHANEDIOL, DNA (5'-D(*TP*AP*CP*AP*CP*GP*TP*GP*TP*A)-3'), Transcription factor 4 | Authors: | Horton, J.R, Cheng, X, Yang, J. | Deposit date: | 2019-03-25 | Release date: | 2019-05-29 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.699 Å) | Cite: | Structural basis for preferential binding of human TCF4 to DNA containing 5-carboxylcytosine. Nucleic Acids Res., 47, 2019
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6KE1
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![BU of 6ke1 by Molmil](/molmil-images/mine/6ke1) | Crystal structure of TtCas1 | Descriptor: | CRISPR-associated endonuclease Cas1 2 | Authors: | Wang, Y.L, Li, J.Z, Yang, J, Wang, J.Y. | Deposit date: | 2019-07-03 | Release date: | 2019-12-18 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.39 Å) | Cite: | Crystal structure of Cas1 in complex with branched DNA. Sci China Life Sci, 63, 2020
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6KDV
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![BU of 6kdv by Molmil](/molmil-images/mine/6kdv) | Crystal structure of TtCas1-DNA complex | Descriptor: | CRISPR-associated endonuclease Cas1 2, DNA (5'-D(*GP*AP*GP*TP*CP*GP*AP*TP*GP*CP*TP*GP*GP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*CP*CP*AP*GP*CP*AP*TP*CP*GP*AP*CP*TP*C)-3') | Authors: | Wang, Y.L, Li, J.Z, Yang, J, Wang, J.Y. | Deposit date: | 2019-07-02 | Release date: | 2019-12-18 | Last modified: | 2020-05-06 | Method: | X-RAY DIFFRACTION (3.11 Å) | Cite: | Crystal structure of Cas1 in complex with branched DNA. Sci China Life Sci, 63, 2020
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1GZN
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![BU of 1gzn by Molmil](/molmil-images/mine/1gzn) | Structure of PKB kinase domain | Descriptor: | RAC-BETA SERINE/THREONINE PROTEIN KINASE | Authors: | Barford, D, Yang, J, Hemmings, B.A. | Deposit date: | 2002-05-24 | Release date: | 2003-05-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Molecular Mechanism for the Regulation of Protein Kinase B/Akt by Hydrophobic Motif Phosphorylation Mol.Cell, 9, 2002
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1GZO
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1GZK
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3R4L
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![BU of 3r4l by Molmil](/molmil-images/mine/3r4l) | Human very long half life Plasminogen Activator Inhibitor type-1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Plasminogen activator inhibitor 1, beta-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Yang, J, Zheng, H, Han, Q, Skrzypczak-Jankun, E, Jankun, J. | Deposit date: | 2011-03-17 | Release date: | 2011-11-02 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Remarkable extension of PAI-1 half-life surprisingly brings no changes to its structure. Int.J.Mol.Med., 29, 2012
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6BZ9
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![BU of 6bz9 by Molmil](/molmil-images/mine/6bz9) | Crystal structure of human caspase-1 in complex with Ac-FLTD-CMK | Descriptor: | Ac-FLTD-CMK, Caspase-1, DI(HYDROXYETHYL)ETHER | Authors: | Xiao, T.S, Yang, J, Liu, Z, Wang, C, Yang, R. | Deposit date: | 2017-12-22 | Release date: | 2018-06-13 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.796 Å) | Cite: | Mechanism of gasdermin D recognition by inflammatory caspases and their inhibition by a gasdermin D-derived peptide inhibitor. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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3G6M
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![BU of 3g6m by Molmil](/molmil-images/mine/3g6m) | crystal structure of a chitinase CrChi1 from the nematophagous fungus Clonostachys rosea in complex with a potent inhibitor caffeine | Descriptor: | CAFFEINE, Chitinase | Authors: | Gan, Z, Yang, J, Lou, Z, Rao, Z, Zhang, K.-Q. | Deposit date: | 2009-02-06 | Release date: | 2010-02-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal structure and mutagenesis analysis of chitinase CrChi1 from the nematophagous fungus Clonostachys rosea in complex with the inhibitor caffeine Microbiology, 156, 2010
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6MG1
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![BU of 6mg1 by Molmil](/molmil-images/mine/6mg1) | C-terminal bZIP domain of human C/EBPbeta with 16bp Methylated Oligonucleotide Containing Consensus Recognition Sequence-C2 Crystal Form | Descriptor: | 1,2-ETHANEDIOL, 16-bp methylated oligonucleotide, CCAAT/enhancer-binding protein beta, ... | Authors: | Horton, J.R, Cheng, X, Yang, J. | Deposit date: | 2018-09-12 | Release date: | 2018-12-12 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural basis for effects of CpA modifications on C/EBP beta binding of DNA. Nucleic Acids Res., 47, 2019
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6MG3
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![BU of 6mg3 by Molmil](/molmil-images/mine/6mg3) | V285A Mutant of the C-terminal bZIP domain of human C/EBPbeta with 16bp Methylated Oligonucleotide Containing Consensus Recognition Sequence | Descriptor: | 1,2-ETHANEDIOL, 16-bp methylated oligonucleotide, CCAAT/enhancer-binding protein beta | Authors: | Horton, J.R, Cheng, X, Yang, J. | Deposit date: | 2018-09-12 | Release date: | 2018-12-12 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural basis for effects of CpA modifications on C/EBP beta binding of DNA. Nucleic Acids Res., 47, 2019
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6MG2
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![BU of 6mg2 by Molmil](/molmil-images/mine/6mg2) | C-terminal bZIP domain of human C/EBPbeta with 16bp Methylated Oligonucleotide Containing Consensus Recognition Sequence-C2221 Crystal Form | Descriptor: | 1,2-ETHANEDIOL, 16-bp methylated oligonucleotide, CCAAT/enhancer-binding protein beta | Authors: | Horton, J.R, Cheng, X, Yang, J. | Deposit date: | 2018-09-12 | Release date: | 2018-12-12 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.928 Å) | Cite: | Structural basis for effects of CpA modifications on C/EBP beta binding of DNA. Nucleic Acids Res., 47, 2019
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2QUR
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![BU of 2qur by Molmil](/molmil-images/mine/2qur) | Crystal Structure of F327A/K285P Mutant of cAMP-dependent Protein Kinase | Descriptor: | 20-mer fragment from cAMP-dependent protein kinase inhibitor alpha, ADENOSINE-5'-DIPHOSPHATE, cAMP-dependent protein kinase, ... | Authors: | Taylor, S.S, Yang, J, Wu, J. | Deposit date: | 2007-08-06 | Release date: | 2008-07-29 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Contribution of non-catalytic core residues to activity and regulation in protein kinase A. J.Biol.Chem., 284, 2009
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