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6NK6
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BU of 6nk6 by Molmil
Electron Cryo-Microscopy Of Chikungunya VLP in complex with mouse Mxra8 receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein, E1 glycoprotein, ...
Authors:Basore, K, Kim, A.S, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-01-04
Release date:2019-05-22
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.06 Å)
Cite:Cryo-EM Structure of Chikungunya Virus in Complex with the Mxra8 Receptor.
Cell, 177, 2019
6ORT
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BU of 6ort by Molmil
Crystal Structure of Bos taurus Mxra8 Ectodomain
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, Matrix remodeling-associated protein 8
Authors:Fremont, D.H, Kim, A.S, Nelson, C.A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-04-30
Release date:2020-03-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:An Evolutionary Insertion in the Mxra8 Receptor-Binding Site Confers Resistance to Alphavirus Infection and Pathogenesis.
Cell Host Microbe, 27, 2020
6PLK
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BU of 6plk by Molmil
Crystal structure of ZIKV-116 Fab in complex with ZIKV envelope DIII
Descriptor: Env, ZIKV-116 heavy chain, ZIKV-116 light chain
Authors:Zhao, H, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-07-01
Release date:2019-11-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mechanism of differential Zika and dengue virus neutralization by a public antibody lineage targeting the DIII lateral ridge.
J.Exp.Med., 217, 2020
8S9G
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BU of 8s9g by Molmil
SARS-CoV-2 BN.1 spike RBD bound to the human ACE2 ectodomain and the S309 neutralizing antibody Fab fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, S309 Fab Heavy chain, ...
Authors:Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:2023-03-28
Release date:2023-10-04
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Neutralization, effector function and immune imprinting of Omicron variants.
Nature, 621, 2023
6MID
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BU of 6mid by Molmil
Cryo-EM structure of the ZIKV virion in complex with Fab fragments of the potently neutralizing human monoclonal antibody ZIKV-195
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E protein, M protein, ...
Authors:Long, F, Rossmann, M.G.
Deposit date:2018-09-19
Release date:2019-01-16
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural basis of a potent human monoclonal antibody against Zika virus targeting a quaternary epitope.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
3N9G
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BU of 3n9g by Molmil
Crystal structure of the Fab fragment of the human neutralizing anti-West Nile Virus MAb CR4354
Descriptor: Fab fragment of MAb CR4354, heavy chain, light chain
Authors:Kaufmann, B, Rossmann, M.G.
Deposit date:2010-05-29
Release date:2010-11-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.434 Å)
Cite:Neutralization of West Nile virus by cross-linking of its surface proteins with Fab fragments of the human monoclonal antibody CR4354.
Proc.Natl.Acad.Sci.USA, 107, 2010
3I50
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BU of 3i50 by Molmil
Crystal structure of the West Nile Virus envelope glycoprotein in complex with the E53 antibody Fab
Descriptor: Envelope glycoprotein, murine heavy chain (IgG3) of E53 monoclonal antibody Fab, murine kappa light chain of E53 monoclonal antibody Fab
Authors:Nybakken, G.E, Warren, J.T, Chen, B.R, Nelson, C.A, Fremont, D.H.
Deposit date:2009-07-03
Release date:2009-10-27
Last modified:2013-09-25
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for the preferential recognition of immature flaviviruses by a fusion-loop antibody.
Embo J., 28, 2009
3IYW
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BU of 3iyw by Molmil
West Nile virus in complex with Fab fragments of MAb CR4354 (fitted coordinates of envelope proteins and Fab fragments of one icosahedral ASU)
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-alpha-D-glucopyranose, CR4354 Fab fragment X1, heavy chain H, ...
Authors:Rossmann, M.G, Kaufmann, B.
Deposit date:2010-06-18
Release date:2010-11-24
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (13.7 Å)
Cite:Neutralization of West Nile virus by cross-linking of its surface proteins with Fab fragments of the human monoclonal antibody CR4354.
Proc.Natl.Acad.Sci.USA, 107, 2010
3J2Z
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BU of 3j2z by Molmil
Electron Cryo-microscopy of Chikungunya VLP in complex with neutralizing antibody Fab m10
Descriptor: m10 heavy chain, m10 light chain
Authors:Sun, S, Xiang, Y, Rossmann, M.G.
Deposit date:2013-01-28
Release date:2013-04-24
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (16.9 Å)
Cite:Structural analyses at pseudo atomic resolution of Chikungunya virus and antibodies show mechanisms of neutralization.
Elife, 2, 2013
8DAQ
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BU of 8daq by Molmil
CryoEM structure of Western equine encephalitis virus VLP
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, E1 envelope glycoprotein, E2 envelope glycoprotein
Authors:Zimmerman, M.I, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:2022-06-13
Release date:2023-12-20
Method:ELECTRON MICROSCOPY (4.35 Å)
Cite:Alternate repeat domain usage in an alphavirus entry receptor enables host species expansion
To Be Published
3J2X
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BU of 3j2x by Molmil
Electron Cryo-microscopy of Chikungunya VLP in complex with neutralizing antibody Fab m242
Descriptor: m242 heavy chain, m242 light chain
Authors:Sun, S, Xiang, Y, Rossmann, M.G.
Deposit date:2013-01-28
Release date:2013-04-24
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (15.6 Å)
Cite:Structural analyses at pseudo atomic resolution of Chikungunya virus and antibodies show mechanisms of neutralization.
Elife, 2, 2013
8DAN
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BU of 8dan by Molmil
CryoEM structure of Western equine encephalitis virus VLP in complex with the avian MXRA8 receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, E1 envelope glycoprotein, E2 envelope glycoprotein, ...
Authors:Zimmerman, M.I, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:2022-06-13
Release date:2023-12-20
Method:ELECTRON MICROSCOPY (4.74 Å)
Cite:Alternate domain repeat usage in an alphavirus entry receptor enables host species expansion
To Be Published
3J30
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BU of 3j30 by Molmil
Electron Cryo-microscopy of Chikungunya VLP in complex with neutralizing antibody Fab CHK152
Descriptor: CHK152 heavy chain, CHK152 light chain
Authors:Sun, S, Xiang, Y, Rossmann, M.G.
Deposit date:2013-01-28
Release date:2013-04-24
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (16 Å)
Cite:Structural analyses at pseudo atomic resolution of Chikungunya virus and antibodies show mechanisms of neutralization.
Elife, 2, 2013
8DW2
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BU of 8dw2 by Molmil
Cryo-EM structure of SARS-CoV-2 RBD in complex with anti-SARS-CoV-2 DARPin,SR22, and two antibody Fabs, S309 and CR3022
Descriptor: Antibody CR3022 heavy chain, Antibody CR3022 light chain, Antibody S309 heavy chain, ...
Authors:Kwon, Y.D, Gorman, J, Kwong, P.D.
Deposit date:2022-07-30
Release date:2022-12-07
Last modified:2023-03-15
Method:ELECTRON MICROSCOPY (4.11 Å)
Cite:A potent and broad neutralization of SARS-CoV-2 variants of concern by DARPins.
Nat.Chem.Biol., 19, 2023
3J2Y
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BU of 3j2y by Molmil
Electron Cryo-microscopy of Chikungunya VLP in complex with neutralizing antibody Fab 9.8B
Descriptor: 9.8B heavy chain, 9.8B light chain
Authors:Sun, S, Xiang, Y, Rossmann, M.G.
Deposit date:2013-01-28
Release date:2013-04-24
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (14.9 Å)
Cite:Structural analyses at pseudo atomic resolution of Chikungunya virus and antibodies show mechanisms of neutralization.
Elife, 2, 2013
8DW3
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BU of 8dw3 by Molmil
Cryo-EM structure of SARS-CoV-2 RBD in complex with anti-SARS-CoV-2 DARPin,SR16m, and two antibody Fabs, S309 and CR3022
Descriptor: Anti-SARS-CoV-2 DARPin SR16m, Antibody S309 light chain, Spike protein S1, ...
Authors:Kwon, Y.D, Gorman, J, Kwong, P.D.
Deposit date:2022-07-30
Release date:2022-12-07
Last modified:2023-03-15
Method:ELECTRON MICROSCOPY (4.26 Å)
Cite:A potent and broad neutralization of SARS-CoV-2 variants of concern by DARPins.
Nat.Chem.Biol., 19, 2023
3J2W
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BU of 3j2w by Molmil
Electron cryo-microscopy of Chikungunya virus
Descriptor: Capsid protein, Glycoprotein E1, Glycoprotein E2
Authors:Sun, S, Xiang, Y, Rossmann, M.G.
Deposit date:2013-01-28
Release date:2013-04-24
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Structural analyses at pseudo atomic resolution of Chikungunya virus and antibodies show mechanisms of neutralization.
Elife, 2, 2013
8DWY
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BU of 8dwy by Molmil
Chikungunya VLP in complex with neutralizing Fab CHK-265 (asymmetric unit)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHK-265 heavy chain, CHK-265 light chain, ...
Authors:Adams, L.J, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2022-08-02
Release date:2023-05-31
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:A chikungunya virus-like particle vaccine induces broadly neutralizing and protective antibodies against alphaviruses in humans.
Sci Transl Med, 15, 2023
8DWX
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BU of 8dwx by Molmil
Chikungunya VLP in complex with neutralizing Fab 506.C01 (asymmetric unit)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 506.C01 heavy chain, 506.C01 light chain, ...
Authors:Adams, L.J, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2022-08-02
Release date:2023-05-31
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:A chikungunya virus-like particle vaccine induces broadly neutralizing and protective antibodies against alphaviruses in humans.
Sci Transl Med, 15, 2023
8DWW
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BU of 8dww by Molmil
Chikungunya VLP in complex with neutralizing Fab 506.A08 (asymmetric unit)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 506.A08 heavy chain, 506.A08 light chain, ...
Authors:Adams, L.J, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2022-08-02
Release date:2023-05-31
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:A chikungunya virus-like particle vaccine induces broadly neutralizing and protective antibodies against alphaviruses in humans.
Sci Transl Med, 15, 2023
7Q6E
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BU of 7q6e by Molmil
Beta049 fab in complex with SARS-CoV2 beta-Spike glycoprotein, The Beta mAb response underscores the antigenic distance to other SARS-CoV-2 variants
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-49 heavy chain, ...
Authors:Duyvesteyn, H.M.E, Ren, J, Stuart, D.I.
Deposit date:2021-11-07
Release date:2021-12-15
Last modified:2022-01-26
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants.
Cell Host Microbe, 30, 2022
7Q9M
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BU of 7q9m by Molmil
Beta-53 fab in complex with SARS-CoV-2 beta-Spike glycoprotein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-53 fab heavy chain, ...
Authors:Duyvesteyn, H.M.E, Ren, J, Stuart, D.I.
Deposit date:2021-11-12
Release date:2021-12-15
Last modified:2022-01-26
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants.
Cell Host Microbe, 30, 2022
7Q9P
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BU of 7q9p by Molmil
Beta-06 fab in complex with SARS-CoV-2 beta-Spike glycoprotein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-06 heavy chain, ...
Authors:Duyvesteyn, H.M.E, Ren, J, Stuart, D.I.
Deposit date:2021-11-12
Release date:2021-12-15
Last modified:2022-01-26
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants.
Cell Host Microbe, 30, 2022
7Q9K
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BU of 7q9k by Molmil
Beta-32 fab in complex with SARS-CoV-2 beta-Spike glycoprotein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-32 heavy chain, ...
Authors:Duyvesteyn, H.M.E, Ren, J, Stuart, D.I.
Deposit date:2021-11-12
Release date:2021-12-15
Last modified:2022-01-26
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants.
Cell Host Microbe, 30, 2022
7Q9G
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BU of 7q9g by Molmil
COVOX-222 fab in complex with SARS-CoV-2 beta-Spike glycoprotein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COVOX-222 heavy chain, ...
Authors:Duyvesteyn, H.M.E, Ren, J, Stuart, D.I.
Deposit date:2021-11-12
Release date:2021-12-15
Last modified:2022-01-26
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants.
Cell Host Microbe, 30, 2022

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数据于2024-06-05公开中

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