8DWX

Chikungunya VLP in complex with neutralizing Fab 506.C01 (asymmetric unit)

Summary for 8DWX

Entry DOI	10.2210/pdb8dwx/pdb
EMDB information	27765
Descriptor	E1 glycoprotein, E2 glycoprotein, Capsid protein, ... (6 entities in total)
Functional Keywords	antibody, viral protein-immune system complex, csgid, structural genomics, center for structural genomics of infectious diseases, viral protein/immune system
Biological source	Chikungunya virus strain Senegal 37997 More
Total number of polymer chains	20
Total formula weight	547587.23
Authors	Adams, L.J.,Fremont, D.H.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2022-08-02, release date: 2023-05-31)
Primary citation	Raju, S.,Adams, L.J.,Earnest, J.T.,Warfield, K.,Vang, L.,Crowe Jr., J.E.,Fremont, D.H.,Diamond, M.S. A chikungunya virus-like particle vaccine induces broadly neutralizing and protective antibodies against alphaviruses in humans. Sci Transl Med, 15:eade8273-eade8273, 2023 Cited by PubMed: 37196061 DOI: 10.1126/scitranslmed.ade8273 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.27 Å)

Structure validation