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6IEW
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BU of 6iew by Molmil
The crystal structure of the dNxf2 UBA domain in complex with Panoramix
Descriptor: Fusion protein of Nuclear RNA export factor 2 and Protein panoramix, GLYCEROL
Authors:Huang, Y, Cheng, S.
Deposit date:2018-09-17
Release date:2019-08-21
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A Pandas complex adapted for piRNA-guided transcriptional silencing and heterochromatin formation.
Nat.Cell Biol., 21, 2019
5YGB
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BU of 5ygb by Molmil
Crystal structure of drosophila melanogaster Papi extended Tudor domain mutant - D287A
Descriptor: GH18329p
Authors:Zhang, Y.H, Huang, Y.
Deposit date:2017-09-22
Release date:2018-03-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural insights into the sequence-specific recognition of Piwi byDrosophilaPapi
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6IHJ
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BU of 6ihj by Molmil
Crystal structure of Drosophila Nxf1 NTF2 domain in complex with Nxt1/p15
Descriptor: NTF2-related export protein, Nuclear RNA export factor 1
Authors:Huang, Y, Yuan, X.
Deposit date:2018-09-30
Release date:2019-08-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A Pandas complex adapted for piRNA-guided transcriptional silencing and heterochromatin formation.
Nat.Cell Biol., 21, 2019
5YGC
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BU of 5ygc by Molmil
Crystal structure of Drosophila melanogaster Papi extended Tudor domain
Descriptor: GH18329p
Authors:Zhang, Y.H, Huang, Y.
Deposit date:2017-09-22
Release date:2018-03-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insights into the sequence-specific recognition of Piwi byDrosophilaPapi
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5YGI
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BU of 5ygi by Molmil
Crystal structure of human FPPS in complex with an inhibitor THZ93
Descriptor: Farnesyl pyrophosphate synthase, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Li, X.
Deposit date:2017-09-23
Release date:2018-09-26
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.177 Å)
Cite:The Mevalonate Pathway Is a Druggable Target for Vaccine Adjuvant Discovery.
Cell, 175, 2018
6K5E
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BU of 6k5e by Molmil
Crystal structure of BioH from Klebsiella pneumonia
Descriptor: Pimeloyl-[acyl-carrier protein] methyl ester esterase
Authors:Wang, L, Chen, Y.
Deposit date:2019-05-28
Release date:2019-07-17
Last modified:2020-05-06
Method:X-RAY DIFFRACTION (2.257 Å)
Cite:Structural insight into the carboxylesterase BioH from Klebsiella pneumoniae.
Biochem.Biophys.Res.Commun., 520, 2019
5XGV
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BU of 5xgv by Molmil
The structure of Diels-Alderase PyrE3 in the biosynthetic pathway of pyrroindomycins
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, PyrE3
Authors:Pan, L, Gong, Y, Guo, Y.
Deposit date:2017-04-18
Release date:2018-04-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.099 Å)
Cite:Structural Insights into a Flavin-Dependent [4 + 2] Cyclase that Catalyzes trans-Decalin Formation in Pyrroindomycin Biosynthesis.
Cell Chem Biol, 25, 2018
5XKJ
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BU of 5xkj by Molmil
Crystal structure of plant receptor ERL1-TMM in complexe with EPF2
Descriptor: LRR receptor-like serine/threonine-protein kinase ERL1, Protein EPIDERMAL PATTERNING FACTOR 2, Protein TOO MANY MOUTHS
Authors:Chai, J, Lin, G.
Deposit date:2017-05-07
Release date:2019-01-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.475 Å)
Cite:A receptor-like protein acts as a specificity switch for the regulation of stomatal development.
Genes Dev., 31, 2017
7E2G
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BU of 7e2g by Molmil
Cryo-EM structure of hDisp1NNN-3C
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Protein dispatched homolog 1,Protein dispatched homolog 1
Authors:Li, W, Wang, L, Gong, X.
Deposit date:2021-02-05
Release date:2021-12-08
Method:ELECTRON MICROSCOPY (3.61 Å)
Cite:Structural insights into proteolytic activation of the human Dispatched1 transporter for Hedgehog morphogen release.
Nat Commun, 12, 2021
7E2H
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BU of 7e2h by Molmil
Cryo-EM structure of hDisp1NNN-3C-Cleavage
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Protein dispatched homolog 1
Authors:Li, W, Wang, L, Gong, X.
Deposit date:2021-02-05
Release date:2021-12-08
Method:ELECTRON MICROSCOPY (3.68 Å)
Cite:Structural insights into proteolytic activation of the human Dispatched1 transporter for Hedgehog morphogen release.
Nat Commun, 12, 2021
7E2I
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BU of 7e2i by Molmil
Cryo-EM structure of hDisp1NNN-ShhN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Protein dispatched homolog 1, ...
Authors:Li, W, Wang, L, Gong, X.
Deposit date:2021-02-05
Release date:2021-12-08
Method:ELECTRON MICROSCOPY (4.07 Å)
Cite:Structural insights into proteolytic activation of the human Dispatched1 transporter for Hedgehog morphogen release.
Nat Commun, 12, 2021
8GPX
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BU of 8gpx by Molmil
YFV_E_YD73Fab_postfusion
Descriptor: Envelope protein, YD73Fab_H, YD73Fab_K
Authors:Li, Y, Wu, L, Chai, Y, Qi, J, Yan, J, Gao, G.F.
Deposit date:2022-08-27
Release date:2022-11-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:A neutralizing-protective supersite of human monoclonal antibodies for yellow fever virus.
Innovation (N Y), 3, 2022
8GPU
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BU of 8gpu by Molmil
YFV_E_YD6Fab_prefusion
Descriptor: Envelope protein, YD6Fab_H, YD6Fab_L
Authors:Li, Y, Wu, L, Qi, J, Yan, J, Gao, G.F.
Deposit date:2022-08-27
Release date:2022-11-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:A neutralizing-protective supersite of human monoclonal antibodies for yellow fever virus.
Innovation (N Y), 3, 2022
8GPT
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BU of 8gpt by Molmil
YFV_E_YD6scFv_postfusion
Descriptor: Envelope protein, YD6_VH, YD6_VL
Authors:Li, Y, Wu, L, Qi, J, Yan, J, Gao, G.F.
Deposit date:2022-08-27
Release date:2022-11-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.07 Å)
Cite:A neutralizing-protective supersite of human monoclonal antibodies for yellow fever virus.
Innovation (N Y), 3, 2022
7CQH
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BU of 7cqh by Molmil
Complex of TRP_CBS2 and Calmodulin_Clobe
Descriptor: AT15141p, CALCIUM ION, Transient receptor potential protein
Authors:Shen, Z.S.
Deposit date:2020-08-10
Release date:2021-06-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Calmodulin binds to Drosophila TRP with an unexpected mode.
Structure, 29, 2021
7CQP
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BU of 7cqp by Molmil
Complex of TRPC4 and Calmodulin_Nlobe
Descriptor: CALCIUM ION, Calmodulin-1, Peptide from Short transient receptor potential channel 4
Authors:Shen, Z.S.
Deposit date:2020-08-11
Release date:2021-06-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Calmodulin binds to Drosophila TRP with an unexpected mode.
Structure, 29, 2021
7CQV
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BU of 7cqv by Molmil
Complex of TRP_CBS1 and Calmodulin_Nlobe
Descriptor: AT15141p, CALCIUM ION, Transient receptor potential protein
Authors:Shen, Z.S.
Deposit date:2020-08-11
Release date:2021-06-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Calmodulin binds to Drosophila TRP with an unexpected mode.
Structure, 29, 2021
5JYY
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BU of 5jyy by Molmil
Structure-based Tetravalent Zanamivir with Potent Inhibitory Activity against Drug-resistant Influenza Viruses
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-acetamido-2,6-anhydro-4-carbamimidamido-3,4,5-trideoxy-7-O-[(2-methoxyethyl)carbamoyl]-D-glycero-D-galacto-non-2-enon ic acid, CALCIUM ION, ...
Authors:Fu, L, Wu, Y, Bi, Y, Zhang, S, Lv, X, Qi, J, Li, Y, Lu, X, Yan, J, Gao, G.F, Li, X.
Deposit date:2016-05-15
Release date:2016-06-29
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure-Based Tetravalent Zanamivir with Potent Inhibitory Activity against Drug-Resistant Influenza Viruses
J.Med.Chem., 59, 2016
7FC3
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BU of 7fc3 by Molmil
structure of NL63 receptor-binding domain complexed with horse ACE2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ...
Authors:Wang, X.Q, Ge, J.W, Lan, J.
Deposit date:2021-07-13
Release date:2021-09-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Structural insights into the binding of SARS-CoV-2, SARS-CoV, and hCoV-NL63 spike receptor-binding domain to horse ACE2.
Structure, 30, 2022
7FC5
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BU of 7fc5 by Molmil
Crystal structure of SARS-CoV-2 RBD and horse ACE2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, Spike protein S1
Authors:Wang, X.Q, Lan, J, Ge, J.W.
Deposit date:2021-07-13
Release date:2022-06-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.894 Å)
Cite:Structural insights into the binding of SARS-CoV-2, SARS-CoV, and hCoV-NL63 spike receptor-binding domain to horse ACE2.
Structure, 30, 2022
7FC6
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BU of 7fc6 by Molmil
Crystal structure of SARS-CoV RBD and horse ACE2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ...
Authors:Wang, X.Q, Lan, J, Ge, J.W.
Deposit date:2021-07-13
Release date:2022-07-13
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.655 Å)
Cite:Structural insights into the binding of SARS-CoV-2, SARS-CoV, and hCoV-NL63 spike receptor-binding domain to horse ACE2.
Structure, 30, 2022
3CF9
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BU of 3cf9 by Molmil
Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with apigenin
Descriptor: (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one, BENZAMIDINE, ...
Authors:Zhang, L, Wu, D, Liu, W, Shen, X, Jiang, H.
Deposit date:2008-03-03
Release date:2008-12-09
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Three flavonoids targeting the beta-hydroxyacyl-acyl carrier protein dehydratase from Helicobacter pylori: crystal structure characterization with enzymatic inhibition assay
Protein Sci., 17, 2008
7T32
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BU of 7t32 by Molmil
CryoEM structure of the adenosine 2A receptor-BRIL/Anti BRIL Fab complex with ZM241385
Descriptor: 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, Adenosine receptor A2a/Soluble cytochrome b562 Fusion Protein
Authors:Zhang, K.H, Wu, H, Hoppe, N, Manglik, A, Cheng, Y.F.
Deposit date:2021-12-06
Release date:2022-08-10
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Fusion protein strategies for cryo-EM study of G protein-coupled receptors.
Nat Commun, 13, 2022
6CDT
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BU of 6cdt by Molmil
Structure of Human Anaplastic Lymphoma Kinase Domain
Descriptor: ALK tyrosine kinase receptor
Authors:McTigue, M, Deng, Y.L, Liu, W, Brooun, A.
Deposit date:2018-02-09
Release date:2019-02-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Reviving B-Factors: Activating ALK Mutations Increase Protein Dynamics of the Unphosphorylated Kinase.
ACS Med Chem Lett, 9, 2018
7JP0
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BU of 7jp0 by Molmil
Crystal structure of Mpro with inhibitor r1
Descriptor: 3C-like proteinase, DIMETHYL SULFOXIDE, N-[(benzyloxy)carbonyl]-L-valyl-N-{(2R)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide
Authors:Yang, K, Liu, W.
Deposit date:2020-08-07
Release date:2021-10-13
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of Mpro with inhibitor r1
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