8UT8
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![BU of 8ut8 by Molmil](/molmil-images/mine/8ut8) | CryoEM structure of A/Shanghai/1/2013 H7 in complex with polyclonal Fab from mice immunized with H7 stem nanoparticles-15 days post-immunization | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Huang, J, Han, J, Ward, A.B. | Deposit date: | 2023-10-30 | Release date: | 2024-05-08 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Eliciting a single amino acid change by vaccination generates antibody protection against group 1 and group 2 influenza A viruses. Immunity, 57, 2024
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8UWA
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![BU of 8uwa by Molmil](/molmil-images/mine/8uwa) | VH1-18 QxxV class antibody 09-1B12 bound to A/Perth/16/2009 H3N2 hemagglutinin | Descriptor: | 09-1B12 heavy chain, 09-1B12 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Maurer, D.P. | Deposit date: | 2023-11-06 | Release date: | 2024-05-08 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (4.02 Å) | Cite: | Eliciting a single amino acid change by vaccination generates antibody protection against group 1 and group 2 influenza A viruses. Immunity, 57, 2024
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8UT4
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![BU of 8ut4 by Molmil](/molmil-images/mine/8ut4) | CryoEM structure of A/Michigan/45/2015 H1 in complex with flu HA central stem VH1-18 antibody 09-1B12 | Descriptor: | 09-1B12 HC Fv, 09-1B12 LC Fv, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Huang, J, Han, J, Ward, A.B. | Deposit date: | 2023-10-30 | Release date: | 2024-05-08 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Eliciting a single amino acid change by vaccination generates antibody protection against group 1 and group 2 influenza A viruses. Immunity, 57, 2024
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8UT5
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![BU of 8ut5 by Molmil](/molmil-images/mine/8ut5) | CryoEM structure of A/Michigan/45/2015 H1 in complex with flu HA central stem VH1-18 antibody UCA6_N55T | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ... | Authors: | Huang, J, Han, J, Ward, A.B. | Deposit date: | 2023-10-30 | Release date: | 2024-05-08 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Eliciting a single amino acid change by vaccination generates antibody protection against group 1 and group 2 influenza A viruses. Immunity, 57, 2024
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4MTH
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![BU of 4mth by Molmil](/molmil-images/mine/4mth) | Crystal structure of mature human RegIIIalpha | Descriptor: | Regenerating islet-derived protein 3-alpha 15 kDa form, ZINC ION | Authors: | Derebe, M.G. | Deposit date: | 2013-09-19 | Release date: | 2013-11-27 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Antibacterial membrane attack by a pore-forming intestinal C-type lectin. Nature, 505, 2013
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2GOM
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![BU of 2gom by Molmil](/molmil-images/mine/2gom) | |
2GOX
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![BU of 2gox by Molmil](/molmil-images/mine/2gox) | Crystal structure of Efb-C / C3d Complex | Descriptor: | Complement C3, Fibrinogen-binding protein | Authors: | Hammel, M, Geisbrecht, B.V. | Deposit date: | 2006-04-14 | Release date: | 2007-03-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | A structural basis for complement inhibition by Staphylococcus aureus. Nat.Immunol., 8, 2007
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7TE1
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![BU of 7te1 by Molmil](/molmil-images/mine/7te1) | |
4JMR
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![BU of 4jmr by Molmil](/molmil-images/mine/4jmr) | A unique spumavirus gag N-terminal domain with functional properties of orthoretroviral Matrix and Capsid | Descriptor: | Env protein, Gag protein | Authors: | Taylor, I.A, Goldstone, D.C, Flower, T.G, Ball, N.J. | Deposit date: | 2013-03-14 | Release date: | 2013-05-29 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | A Unique Spumavirus Gag N-terminal Domain with Functional Properties of Orthoretroviral Matrix and Capsid. Plos Pathog., 9, 2013
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5NCQ
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![BU of 5ncq by Molmil](/molmil-images/mine/5ncq) | Structure of the (SR) Ca2+-ATPase bound to a Tetrahydrocarbazole and TNP-ATP | Descriptor: | (1~{S})-~{N}-[(4-bromophenyl)methyl]-7-(trifluoromethyloxy)-2,3,4,9-tetrahydro-1~{H}-carbazol-1-amine, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, POTASSIUM ION, ... | Authors: | Bublitz, M, Kjellerup, L, O'Hanlon Cohrt, K, Gordon, S, Mortensen, A.L, Clausen, J.D, Pallin, D, Hansen, J.B, Brown, W.D, Fuglsang, A, Winther, A.-M.L. | Deposit date: | 2017-03-06 | Release date: | 2018-01-10 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Tetrahydrocarbazoles are a novel class of potent P-type ATPase inhibitors with antifungal activity. PLoS ONE, 13, 2018
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3OHX
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![BU of 3ohx by Molmil](/molmil-images/mine/3ohx) | |
4N6T
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![BU of 4n6t by Molmil](/molmil-images/mine/4n6t) | Adhiron: a stable and versatile peptide display scaffold - full length adhiron | Descriptor: | Adhiron | Authors: | Mcpherson, M, Tomlinson, D, Owen, R.L, Nettleship, J.E, Owens, R.J. | Deposit date: | 2013-10-14 | Release date: | 2014-04-09 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Adhiron: a stable and versatile peptide display scaffold for molecular recognition applications. Protein Eng.Des.Sel., 27, 2014
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2HH3
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![BU of 2hh3 by Molmil](/molmil-images/mine/2hh3) | Solution structure of the third KH domain of KSRP | Descriptor: | KH-type splicing regulatory protein | Authors: | Garcia-Mayoral, M.F. | Deposit date: | 2006-06-27 | Release date: | 2007-05-08 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | The Structure of the C-Terminal KH Domains of KSRP Reveals a Noncanonical Motif Important for mRNA Degradation. Structure, 15, 2007
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2HH2
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![BU of 2hh2 by Molmil](/molmil-images/mine/2hh2) | |
3E94
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![BU of 3e94 by Molmil](/molmil-images/mine/3e94) | |
4I1R
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![BU of 4i1r by Molmil](/molmil-images/mine/4i1r) | Human MALT1 (caspase-IG3) in complex with thioridazine | Descriptor: | 10-{2-[(2S)-1-methylpiperidin-2-yl]ethyl}-2-(methylsulfanyl)-10H-phenothiazine, Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | Authors: | Schlauderer, F, Lammens, K, Hopfner, K.P. | Deposit date: | 2012-11-21 | Release date: | 2013-08-28 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural Analysis of Phenothiazine Derivatives as Allosteric Inhibitors of the MALT1 Paracaspase. Angew.Chem.Int.Ed.Engl., 52, 2013
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5M75
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![BU of 5m75 by Molmil](/molmil-images/mine/5m75) | |
2WPQ
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![BU of 2wpq by Molmil](/molmil-images/mine/2wpq) | Salmonella enterica SadA 479-519 fused to GCN4 adaptors (SadAK3, in- register fusion) | Descriptor: | CHLORIDE ION, NITRATE ION, TRIMERIC AUTOTRANSPORTER ADHESIN FRAGMENT | Authors: | Hartmann, M.D, Hernandez Alvarez, B, Albrecht, R, Zeth, K, Lupas, A.N. | Deposit date: | 2009-08-09 | Release date: | 2009-11-03 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | A Coiled-Coil Motif that Sequesters Ions to the Hydrophobic Core. Proc.Natl.Acad.Sci.USA, 106, 2009
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5O35
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![BU of 5o35 by Molmil](/molmil-images/mine/5o35) | Structure of complement proteins complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, Complement factor H,Complement factor H | Authors: | Xue, X, Wu, J, Forneris, F, Gros, P. | Deposit date: | 2017-05-23 | Release date: | 2017-06-28 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (4.2 Å) | Cite: | Regulator-dependent mechanisms of C3b processing by factor I allow differentiation of immune responses. Nat. Struct. Mol. Biol., 24, 2017
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5O32
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![BU of 5o32 by Molmil](/molmil-images/mine/5o32) | The structure of complement complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Xue, X, Wu, J, Forneris, F, Gros, P. | Deposit date: | 2017-05-23 | Release date: | 2017-06-28 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (4.206209 Å) | Cite: | Regulator-dependent mechanisms of C3b processing by factor I allow differentiation of immune responses. Nat. Struct. Mol. Biol., 24, 2017
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4CI9
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![BU of 4ci9 by Molmil](/molmil-images/mine/4ci9) | Crystal structure of cathepsin A, apo-structure | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, DIMETHYL SULFOXIDE, ... | Authors: | Schreuder, H.A, Liesum, A, Kroll, K, Boehnisch, B, Buning, C, Ruf, S, Buning, C, Sadowski, T. | Deposit date: | 2013-12-06 | Release date: | 2014-02-26 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Crystal structure of cathepsin A, a novel target for the treatment of cardiovascular diseases. Biochem. Biophys. Res. Commun., 445, 2014
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4CIB
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![BU of 4cib by Molmil](/molmil-images/mine/4cib) | crystal structure of cathepsin a, complexed with compound 2 | Descriptor: | 2-(cyclohexylmethyl)propanedioic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, ... | Authors: | Schreuder, H.A, Liesum, A, Kroll, K, Boehnisch, B, Buning, C, Ruf, S, Buning, C, Sadowski, T. | Deposit date: | 2013-12-06 | Release date: | 2014-02-26 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Crystal structure of cathepsin A, a novel target for the treatment of cardiovascular diseases. Biochem. Biophys. Res. Commun., 445, 2014
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4CIA
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![BU of 4cia by Molmil](/molmil-images/mine/4cia) | Crystal structure of cathepsin A, complexed with compound 1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, LYSOSOMAL PROTECTIVE PROTEIN, ... | Authors: | Schreuder, H.A, Liesum, A, Kroll, K, Boehnisch, B, Buning, C, Ruf, S, Buning, C, Sadowski, T. | Deposit date: | 2013-12-06 | Release date: | 2014-02-26 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Crystal structure of cathepsin A, a novel target for the treatment of cardiovascular diseases. Biochem. Biophys. Res. Commun., 445, 2014
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4PUZ
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![BU of 4puz by Molmil](/molmil-images/mine/4puz) | |
4PV0
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![BU of 4pv0 by Molmil](/molmil-images/mine/4pv0) | Crystal structure of spleen tyrosine kinase (Syk) in complex with an imidazopyrazine inhibitor | Descriptor: | 4-[(3-{8-[(3,4-dimethoxyphenyl)amino]imidazo[1,2-a]pyrazin-6-yl}benzoyl)amino]benzoic acid, CHLORIDE ION, Tyrosine-protein kinase SYK | Authors: | Lansdon, E.B, Mitchell, S.A. | Deposit date: | 2014-03-14 | Release date: | 2014-05-21 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Discovery of GS-9973, a Selective and Orally Efficacious Inhibitor of Spleen Tyrosine Kinase. J.Med.Chem., 57, 2014
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