7XPD
 
 | | Cryo-EM structure of the T=3 lake sinai virus 2 virus-like capsid at pH 6.5 | | Descriptor: | Capsid protein alpha | | Authors: | Chen, N.C, Wang, C.H, Chen, C.J, Yoshimura, M, Guan, H.H, Chuankhayan, P, Lin, C.C. | | Deposit date: | 2022-05-04 | | Release date: | 2023-02-08 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (3.74 Å) | | Cite: | Structures of honeybee-infecting Lake Sinai virus reveal domain functions and capsid assembly with dynamic motions.
Nat Commun, 14, 2023
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7EXH
 | | Crystal structure of D383A mutant from Arabidopsis thaliana complexed with Galactinol. | | Descriptor: | Probable galactinol--sucrose galactosyltransferase 6, galactinol | | Authors: | Chuankhayan, P, Guan, H.H, Lin, C.C, Chen, N.C, Huang, Y.C, Yoshimura, M, Nakagawa, A, Lee, R.H, Chen, C.J. | | Deposit date: | 2021-05-27 | | Release date: | 2022-11-30 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.63 Å) | | Cite: | Structural insight into the hydrolase and synthase activities of an alkaline alpha-galactosidase from Arabidopsis from complexes with substrate/product.
Acta Crystallogr D Struct Biol, 79, 2023
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7EXF
 | | Crystal structure of wild-type from Arabidopsis thaliana complexed with Galactose | | Descriptor: | Probable galactinol--sucrose galactosyltransferase 6, beta-D-galactopyranose | | Authors: | Chuankhayan, P, Guan, H.H, Lin, C.C, Chen, N.C, Huang, Y.C, Yoshimura, M, Nakagawa, A, Lee, R.H, Chen, C.J. | | Deposit date: | 2021-05-27 | | Release date: | 2022-11-30 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.17 Å) | | Cite: | Structural insight into the hydrolase and synthase activities of an alkaline alpha-galactosidase from Arabidopsis from complexes with substrate/product.
Acta Crystallogr D Struct Biol, 79, 2023
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7EXR
 | | Crystal structure of alkaline alpha-galactosidase D383A mutant from Arabidopsis thaliana complexed with Stachyose. | | Descriptor: | Probable galactinol--sucrose galactosyltransferase 6, alpha-D-galactopyranose-(1-6)-alpha-D-galactopyranose-(1-6)-alpha-D-glucopyranose-(1-2)-beta-D-fructofuranose | | Authors: | Chuankhayan, P, Guan, H.H, Lin, C.C, Chen, N.C, Huang, Y.C, Yoshimura, M, Nakagawa, A, Lee, R.H, Chen, C.J. | | Deposit date: | 2021-05-28 | | Release date: | 2022-11-30 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural insight into the hydrolase and synthase activities of an alkaline alpha-galactosidase from Arabidopsis from complexes with substrate/product.
Acta Crystallogr D Struct Biol, 79, 2023
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7EXJ
 | | Crystal structure of alkaline alpha-galctosidase D383A mutant from Arabidopsis thaliana complexed with Raffinose | | Descriptor: | Probable galactinol--sucrose galactosyltransferase 6, alpha-D-galactopyranose-(1-6)-alpha-D-glucopyranose-(1-2)-beta-D-fructofuranose | | Authors: | Chuankhayan, P, Guan, H.H, Lin, C.C, Chen, N.C, Huang, Y.C, Yoshimura, M, Nakagawa, A, Lee, R.H, Chen, C.J. | | Deposit date: | 2021-05-27 | | Release date: | 2022-11-30 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.47 Å) | | Cite: | Structural insight into the hydrolase and synthase activities of an alkaline alpha-galactosidase from Arabidopsis from complexes with substrate/product.
Acta Crystallogr D Struct Biol, 79, 2023
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7EXG
 | | Crystal structure of D383A mutant from Arabidopsis thaliana complexed with Galactose. | | Descriptor: | Probable galactinol--sucrose galactosyltransferase 6, beta-D-galactopyranose | | Authors: | Chuankhayan, P, Guan, H.H, Lin, C.C, Chen, N.C, Huang, Y.C, Yoshimura, M, Nakagawa, A, Lee, R.H, Chen, C.J. | | Deposit date: | 2021-05-27 | | Release date: | 2022-11-30 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structural insight into the hydrolase and synthase activities of an alkaline alpha-galactosidase from Arabidopsis from complexes with substrate/product.
Acta Crystallogr D Struct Biol, 79, 2023
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7EXQ
 | | Crystal structure of alkaline alpha-galactosidase D383A mutant from Arabidopsis thaliana complexed with product-galactose and sucrose. | | Descriptor: | Probable galactinol--sucrose galactosyltransferase 6, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, beta-D-galactopyranose | | Authors: | Chuankhayan, P, Guan, H.H, Lin, C.C, Chen, N.C, Huang, Y.C, Yoshimura, M, Nakagawa, A, Lee, R.H, Chen, C.J. | | Deposit date: | 2021-05-28 | | Release date: | 2022-11-30 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural insight into the hydrolase and synthase activities of an alkaline alpha-galactosidase from Arabidopsis from complexes with substrate/product.
Acta Crystallogr D Struct Biol, 79, 2023
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1A1T
 | | STRUCTURE OF THE HIV-1 NUCLEOCAPSID PROTEIN BOUND TO THE SL3 PSI-RNA RECOGNITION ELEMENT, NMR, 25 STRUCTURES | | Descriptor: | NUCLEOCAPSID PROTEIN, SL3 STEM-LOOP RNA, ZINC ION | | Authors: | De Guzman, R.N, Wu, Z.R, Stalling, C.C, Pappalardo, L, Borer, P.N, Summers, M.F. | | Deposit date: | 1997-12-15 | | Release date: | 1998-06-17 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structure of the HIV-1 nucleocapsid protein bound to the SL3 psi-RNA recognition element.
Science, 279, 1998
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6KDP
 | | Crystal structure of human DNMT3B-DNMT3L complex (II) | | Descriptor: | DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, FORMIC ACID, ... | | Authors: | Lin, C.-C, Chen, Y.-P, Yang, W.-Z, Shen, C.-K, Yuan, H.S. | | Deposit date: | 2019-07-02 | | Release date: | 2020-02-19 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.93 Å) | | Cite: | Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B.
Nucleic Acids Res., 48, 2020
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6KDB
 | | Crystal structure of human DNMT3B-DNMT3L in complex with DNA containing CpGpT site | | Descriptor: | DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ... | | Authors: | Lin, C.-C, Chen, Y.-P, Yang, W.-Z, Shen, C.-K, Yuan, H.S. | | Deposit date: | 2019-07-01 | | Release date: | 2020-02-19 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.862 Å) | | Cite: | Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B.
Nucleic Acids Res., 48, 2020
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6KDT
 | | Crystal structure of human DNMT3B (Q772R)-DNMT3L complex | | Descriptor: | DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, FORMIC ACID, ... | | Authors: | Lin, C.-C, Chen, Y.-P, Yang, W.-Z, Shen, C.-K, Yuan, H.S. | | Deposit date: | 2019-07-02 | | Release date: | 2020-02-19 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.87 Å) | | Cite: | Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B.
Nucleic Acids Res., 48, 2020
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6KDA
 | | Crystal structure of human DNMT3B-DNMT3L in complex with DNA containing CpGpG site | | Descriptor: | DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ... | | Authors: | Lin, C.-C, Chen, Y.-P, Yang, W.-Z, Shen, C.-K, Yuan, H.S. | | Deposit date: | 2019-07-01 | | Release date: | 2020-02-19 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.909 Å) | | Cite: | Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B.
Nucleic Acids Res., 48, 2020
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6KDL
 | | Crystal structure of human DNMT3B-DNMT3L complex (I) | | Descriptor: | DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, S-ADENOSYL-L-HOMOCYSTEINE | | Authors: | Lin, C.-C, Chen, Y.-P, Yang, W.-Z, Shen, C.-K, Yuan, H.S. | | Deposit date: | 2019-07-02 | | Release date: | 2020-02-19 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.274 Å) | | Cite: | Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B.
Nucleic Acids Res., 48, 2020
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6V6Q
 | | Crystal Structure of Monophosphorylated FGF Receptor 2 isoform IIIb with PTR657 | | Descriptor: | Fibroblast growth factor receptor 2, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | | Authors: | Lin, C.-C, Wieteska, L, Poncet-Montange, G, Suen, K.M, Arold, S.T, Ahmed, Z, Ladbury, J.E. | | Deposit date: | 2019-12-05 | | Release date: | 2020-11-11 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.46 Å) | | Cite: | The combined action of the intracellular regions regulates FGFR2 kinase activity
Commun Biol, 6, 2023
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3EGA
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3EGB
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3T8S
 | | Apo and InsP3-bound Crystal Structures of the Ligand-Binding Domain of an InsP3 Receptor | | Descriptor: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate receptor type 1 | | Authors: | Lin, C, Baek, K, Lu, Z. | | Deposit date: | 2011-08-01 | | Release date: | 2011-09-07 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3.77 Å) | | Cite: | Apo and InsP(3)-bound crystal structures of the ligand-binding domain of an InsP(3) receptor.
Nat.Struct.Mol.Biol., 18, 2011
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4WIZ
 | | Crystal structure of Grouper nervous necrosis virus-like particle at 3.6A | | Descriptor: | CALCIUM ION, Coat protein | | Authors: | Chen, N.C, Chen, C.J, Yoshimura, M, Guan, H.H, Chen, T.Y. | | Deposit date: | 2014-09-28 | | Release date: | 2015-10-07 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | Crystal Structures of a Piscine Betanodavirus: Mechanisms of Capsid Assembly and Viral Infection
Plos Pathog., 11, 2015
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7YPL
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7OZD
 | | FGFR1 kinase domain (residues 458-765) with mutations C488A, C584S in complex with 34. | | Descriptor: | 1,2-ETHANEDIOL, Fibroblast growth factor receptor 1, N-[6-(4-hydroxyphenyl)-1H-indazol-3-yl]benzamide, ... | | Authors: | Trinh, C.H, Turner, L.D, Fishwick, C.W.G. | | Deposit date: | 2021-06-27 | | Release date: | 2021-12-01 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | From Fragment to Lead: De Novo Design and Development toward a Selective FGFR2 Inhibitor.
J.Med.Chem., 65, 2022
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7OZB
 | | FGFR1 kinase domain (residues 458-765) with mutations C488A, C584S in complex with 38. | | Descriptor: | 1,2-ETHANEDIOL, 4-[3-(4-piperazin-4-ium-1-ylphenyl)-1H-indazol-6-yl]phenol, Fibroblast growth factor receptor 1, ... | | Authors: | Trinh, C.H, Turner, L.D, Fishwick, C.W.G. | | Deposit date: | 2021-06-27 | | Release date: | 2021-12-01 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.71 Å) | | Cite: | From Fragment to Lead: De Novo Design and Development toward a Selective FGFR2 Inhibitor.
J.Med.Chem., 65, 2022
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7OZF
 | | FGFR1 kinase domain (residues 458-765) with mutations C488A, C584S in complex with 19. | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Fibroblast growth factor receptor 1, ... | | Authors: | Trinh, C.H, Turner, L.D, Fishwick, C.W.G. | | Deposit date: | 2021-06-28 | | Release date: | 2021-12-01 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | From Fragment to Lead: De Novo Design and Development toward a Selective FGFR2 Inhibitor.
J.Med.Chem., 65, 2022
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7OZY
 | | FGFR2 kinase domain (residues 461-763) in complex with 38. | | Descriptor: | 1,2-ETHANEDIOL, 4-[3-(4-piperazin-4-ium-1-ylphenyl)-1H-indazol-6-yl]phenol, Fibroblast growth factor receptor 2, ... | | Authors: | Trinh, C.H, Turner, L.D, Fishwick, C.W.G. | | Deposit date: | 2021-06-29 | | Release date: | 2021-12-01 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.28 Å) | | Cite: | From Fragment to Lead: De Novo Design and Development toward a Selective FGFR2 Inhibitor.
J.Med.Chem., 65, 2022
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4RFU
 | | Crystal structure of truncated P-domain from Grouper nervous necrosis virus capsid protein at 1.2A | | Descriptor: | CALCIUM ION, Coat protein, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Chen, N.C, Chen, C.J, Yoshimura, M, Guan, H.H, Chen, T.Y. | | Deposit date: | 2014-09-27 | | Release date: | 2015-10-07 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Crystal Structures of a Piscine Betanodavirus: Mechanisms of Capsid Assembly and Viral Infection
Plos Pathog., 11, 2015
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4RFT
 | | T=1 subviral particle of Grouper nervous necrosis virus capsid protein deletion mutant (delta 1-34 & 218-338) | | Descriptor: | Coat protein | | Authors: | Chen, N.C, Chen, C.J, Yoshimura, M, Guan, H.H, Chen, T.Y. | | Deposit date: | 2014-09-27 | | Release date: | 2015-10-07 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Crystal Structures of a Piscine Betanodavirus: Mechanisms of Capsid Assembly and Viral Infection
Plos Pathog., 11, 2015
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