7NRX
| Straight filament from Alzheimer's disease with PET ligand APN-1607 | Descriptor: | Microtubule-associated protein tau | Authors: | Shi, Y, Murzin, A.G, Falcon, B, Epstein, A, Machin, J, Tempest, P, Newell, K.L, Vidal, R, Garringer, H.J, Sahara, N, Higuchi, M, Ghetti, B, Jang, M, Scheres, S.H.W, Goedert, M. | Deposit date: | 2021-03-04 | Release date: | 2021-03-24 | Last modified: | 2021-04-28 | Method: | ELECTRON MICROSCOPY (3.55 Å) | Cite: | Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607. Acta Neuropathol, 141, 2021
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7NRS
| Conformation 1 of straight filament from primary age-related tauopathy brain | Descriptor: | Microtubule-associated protein tau | Authors: | Shi, Y, Murzin, A.G, Falcon, B, Epstein, A, Machin, J, Tempest, P, Newell, K.L, Vidal, R, Garringer, H.J, Sahara, N, Higuchi, M, Ghetti, B, Jang, M, Scheres, S.H.W, Goedert, M. | Deposit date: | 2021-03-04 | Release date: | 2021-03-24 | Last modified: | 2021-04-28 | Method: | ELECTRON MICROSCOPY (2.68 Å) | Cite: | Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607. Acta Neuropathol, 141, 2021
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8OTD
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8OTH
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8OT6
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8OTJ
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8OTF
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8OT9
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8OTI
| CTE typeIII tau filament | Descriptor: | Microtubule-associated protein tau | Authors: | Tetter, S, Qi, C, Ryskeldi-Falcon, B, Scheres, S.H.W, Goedert, M. | Deposit date: | 2023-04-20 | Release date: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold. Proc.Natl.Acad.Sci.USA, 120, 2023
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8OTC
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8OTG
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8OTE
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8P34
| Tau filaments extracted from human brain with the DeltaK281 mutation in MAPT | Descriptor: | Microtubule-associated protein tau | Authors: | Schweighauser, M, Garringer, H.J, Klingstedt, T, Masuda-Suzukake, M, Murrell, J.R, Vidal, R, Scheres, S.H.W, Goedert, M, Ghetti, B, Newell, K.L. | Deposit date: | 2023-05-17 | Release date: | 2023-07-05 | Last modified: | 2023-07-19 | Method: | ELECTRON MICROSCOPY (2.61 Å) | Cite: | Mutation ∆K281 in MAPT causes Pick's disease. Acta Neuropathol, 146, 2023
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8Q92
| P301S Tau Filaments from the Brains of PS19 Transgenic Mouse Line | Descriptor: | Microtubule-associated protein tau | Authors: | Schweighauser, M, Murzin, A.G, Macdonald, J, Lavenir, I, Crowther, R.A, Scheres, S.H.W, Goedert, M. | Deposit date: | 2023-08-19 | Release date: | 2023-10-11 | Last modified: | 2023-10-18 | Method: | ELECTRON MICROSCOPY (3.05 Å) | Cite: | Cryo-EM structures of tau filaments from the brains of mice transgenic for human mutant P301S Tau. Acta Neuropathol Commun, 11, 2023
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8Q96
| P301S Tau Filaments from the Brains of Tg2541 Transgenic Mouse Line | Descriptor: | Isoform Tau-E of Microtubule-associated protein tau, Unknown protein | Authors: | Schweighauser, M, Murzin, A.G, Macdonald, J, Lavenir, I, Crowther, R.A, Scheres, S.H.W, Goedert, M. | Deposit date: | 2023-08-19 | Release date: | 2023-10-11 | Last modified: | 2023-10-18 | Method: | ELECTRON MICROSCOPY (3.09 Å) | Cite: | Cryo-EM structures of tau filaments from the brains of mice transgenic for human mutant P301S Tau. Acta Neuropathol Commun, 11, 2023
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8ORF
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8ORE
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8ORG
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8PPO
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8Q27
| Tau: AD-MIA1 | Descriptor: | Isoform Tau-D of Microtubule-associated protein tau | Authors: | Lovestam, S, Scheres, S.H.W, Goedert, M, Li, D. | Deposit date: | 2023-08-01 | Release date: | 2023-08-30 | Last modified: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (2.02 Å) | Cite: | Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
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8Q2J
| Tau - AD-MIA2 | Descriptor: | Isoform Tau-D of Microtubule-associated protein tau | Authors: | Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. | Deposit date: | 2023-08-02 | Release date: | 2023-08-30 | Last modified: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (2.23 Å) | Cite: | Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
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8Q7L
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8Q7F
| Tau - AD-MIA5 | Descriptor: | Isoform Tau-D of Microtubule-associated protein tau | Authors: | Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. | Deposit date: | 2023-08-16 | Release date: | 2023-08-30 | Last modified: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (3.72 Å) | Cite: | Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
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8Q7M
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8Q2K
| Tau - AD-MIA3 | Descriptor: | Isoform Tau-D of Microtubule-associated protein tau | Authors: | Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. | Deposit date: | 2023-08-02 | Release date: | 2023-08-30 | Last modified: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (2.88 Å) | Cite: | Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
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