1S5H
 
 | | Potassium Channel Kcsa-Fab Complex T75C mutant in K+ | | Descriptor: | ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, DIACYL GLYCEROL, ... | | Authors: | Mackinnon, R, Zhou, M. | | Deposit date: | 2004-01-20 | | Release date: | 2004-05-18 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | A mutant KcsA K(+) channel with altered conduction properties and selectivity filter ion distribution.
J.Mol.Biol., 338, 2004
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8K5R
 | | CDK9/cyclin T1 in complex with KB-0742 | | Descriptor: | (1S,3S)-N3-(5-pentan-3-ylpyrazolo[1,5-a]pyrimidin-7-yl)cyclopentane-1,3-diamine, Cyclin-T1, Cyclin-dependent kinase 9 | | Authors: | Zhou, M, Li, H, Gao, H, Trotter, B.W, Freeman, D. | | Deposit date: | 2023-07-24 | | Release date: | 2023-12-06 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (3.751 Å) | | Cite: | Discovery of KB-0742, a Potent, Selective, Orally Bioavailable Small Molecule Inhibitor of CDK9 for MYC-Dependent Cancers.
J.Med.Chem., 66, 2023
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3CDK
 | | Crystal structure of the co-expressed succinyl-CoA transferase A and B complex from Bacillus subtilis | | Descriptor: | Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A, Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B | | Authors: | Kim, Y, Zhou, M, Stols, L, Eschenfeldt, W, Donnelly, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2008-02-27 | | Release date: | 2008-03-18 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.59 Å) | | Cite: | Crystal structure of the co-expressed succinyl-CoA transferase A and B complex from Bacillus subtilis.
To be Published
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4N7X
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5IWS
 | | Crystal structure of the transporter MalT, the EIIC domain from the maltose-specific phosphotransferase system | | Descriptor: | Protein-N(Pi)-phosphohistidine-sugar phosphotransferase (Enzyme II of the phosphotransferase system) (PTS system glucose-specific IIBC component), alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | Authors: | McCoy, J.G, Ren, Z, Levin, E.J, Zhou, M, New York Consortium on Membrane Protein Structure (NYCOMPS) | | Deposit date: | 2016-03-22 | | Release date: | 2016-05-25 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.551 Å) | | Cite: | The Structure of a Sugar Transporter of the Glucose EIIC Superfamily Provides Insight into the Elevator Mechanism of Membrane Transport.
Structure, 24, 2016
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4EZC
 | | Crystal Structure of the UT-B Urea Transporter from Bos Taurus | | Descriptor: | OCTANOIC ACID (2-HYDROXY-1-HYDROXYMETHYL-HEPTADEC-3-ENYL)-AMIDE, Urea transporter 1, beta-D-glucopyranose, ... | | Authors: | Cao, Y, Levin, E.J, Zhou, M, New York Consortium on Membrane Protein Structure (NYCOMPS) | | Deposit date: | 2012-05-02 | | Release date: | 2012-06-27 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.36 Å) | | Cite: | Structure and permeation mechanism of a mammalian urea transporter.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4EZD
 | | Crystal Structure of the UT-B Urea Transporter from Bos Taurus Bound to Selenourea | | Descriptor: | OCTANOIC ACID (2-HYDROXY-1-HYDROXYMETHYL-HEPTADEC-3-ENYL)-AMIDE, Urea transporter 1, beta-D-glucopyranose, ... | | Authors: | Cao, Y, Levin, E.J, Zhou, M, New York Consortium on Membrane Protein Structure (NYCOMPS) | | Deposit date: | 2012-05-02 | | Release date: | 2012-06-27 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure and permeation mechanism of a mammalian urea transporter.
Proc.Natl.Acad.Sci.USA, 109, 2012
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3BWL
 | | Crystal structure of PAS domain of HTR-like protein from Haloarcula marismortui | | Descriptor: | 1H-INDOLE-3-CARBALDEHYDE, MAGNESIUM ION, Sensor protein | | Authors: | Osipiuk, J, Zhou, M, Freeman, L, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2008-01-09 | | Release date: | 2008-01-15 | | Last modified: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (1.73 Å) | | Cite: | X-ray crystal structure of PAS domain of HTR-like protein from Haloarcula marismortui.
To be Published
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2QH9
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5JCV
 | | Sortase B from Listeria monocytogenes. | | Descriptor: | CHLORIDE ION, Lmo2181 protein, SULFATE ION | | Authors: | Osipiuk, J, Zhou, M, Grimshaw, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2016-04-15 | | Release date: | 2016-04-27 | | Last modified: | 2019-12-11 | | Method: | X-RAY DIFFRACTION (2.23 Å) | | Cite: | Sortase B from Listeria monocytogenes.
to be published
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3U1B
 | | Crystal structure of the S238R mutant of mycrocine immunity protein (MccF) with AMP | | Descriptor: | ADENOSINE MONOPHOSPHATE, Microcin immunity protein MccF | | Authors: | Nocek, B, Gu, M, Zhou, M, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2011-09-29 | | Release date: | 2011-11-30 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.604 Å) | | Cite: | Structural and Functional Characterization of Microcin C Resistance Peptidase MccF from Bacillus anthracis.
J.Mol.Biol., 420, 2012
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3TYX
 | | Crystal structure of the F177S mutant of mycrocine immunity protein (MccF) with AMP | | Descriptor: | ADENOSINE MONOPHOSPHATE, Microcin immunity protein MccF | | Authors: | Nocek, B, Gu, M, Zhou, M, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2011-09-26 | | Release date: | 2011-12-28 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.04 Å) | | Cite: | Structural and Functional Characterization of Microcin C Resistance Peptidase MccF from Bacillus anthracis.
J.Mol.Biol., 420, 2012
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4FCA
 | | The crystal structure of a functionally unknown conserved protein from Bacillus anthracis str. Ames. | | Descriptor: | Conserved domain protein, IMIDAZOLE, NICKEL (II) ION | | Authors: | Tan, K, Zhou, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2012-05-24 | | Release date: | 2012-06-06 | | Method: | X-RAY DIFFRACTION (2.055 Å) | | Cite: | The crystal structure of a functionally unknown conserved protein from Bacillus anthracis str. Ames.
To be Published
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8UUK
 | | Pendrin in apo | | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, CHOLESTEROL, Lauryl Maltose Neopentyl Glycol, ... | | Authors: | Wang, L, Hoang, A, Zhou, M. | | Deposit date: | 2023-11-01 | | Release date: | 2024-02-07 | | Last modified: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Mechanism of anion exchange and small-molecule inhibition of pendrin.
Nat Commun, 15, 2024
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2QZI
 | | The crystal structure of a conserved protein of unknown function from Streptococcus thermophilus LMG 18311. | | Descriptor: | 1,2-ETHANEDIOL, SODIUM ION, Uncharacterized protein | | Authors: | Tan, K, Zhou, M, Freeman, L, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2007-08-16 | | Release date: | 2007-08-28 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The crystal structure of a conserved protein of unknown function from Streptococcus thermophilus LMG 18311.
To be Published
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4NMU
 | | Crystal Structure of Thiol-disulfide Oxidoreductase from Bacillus str. 'Ames Ancestor' | | Descriptor: | 1,2-ETHANEDIOL, ACETIC ACID, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Kim, Y, Zhou, M, Shatsman, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2013-11-15 | | Release date: | 2013-12-18 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Crystal Structure of Thiol-disulfide Oxidoreductase from Bacillus str. 'Ames Ancestor'
To be Published
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3UFG
 | | The crystal structure of glycyl-tRNA synthetase subunit alpha from Campylobacter jejuni subsp. jejuni NCTC in complex with ATP | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Glycyl-tRNA synthetase alpha subunit, LEUCINE | | Authors: | Tan, K, Zhou, M, Peterson, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2011-11-01 | | Release date: | 2011-11-09 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.552 Å) | | Cite: | The crystal structure of glycyl-tRNA synthetase subunit alpha from Campylobacter jejuni subsp. jejuni NCTC in complex with ATP
To be Published
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4XBO
 | | Crystal structure of full length E.coli TrmJ in complex with SAH | | Descriptor: | S-ADENOSYL-L-HOMOCYSTEINE, tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | | Authors: | Liu, R.J, Long, T, Zhou, M, Wang, E.D. | | Deposit date: | 2014-12-17 | | Release date: | 2015-12-23 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | tRNA recognition by a bacterial tRNA Xm32 modification enzyme from the SPOUT methyltransferase superfamily
Nucleic Acids Res., 43, 2015
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7TBS
 | | Crystal Structure of the Glutaredoxin 2 from Francisella tularensis | | Descriptor: | CHLORIDE ION, Glutaredoxin 2, SULFATE ION | | Authors: | Kim, Y, Zhou, M, Grimshaw, S, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2021-12-22 | | Release date: | 2022-01-05 | | Method: | X-RAY DIFFRACTION (1.96 Å) | | Cite: | Crystal Structure of the Glutaredoxin 2 from Francisella tularensis
To Be Published
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4RQW
 | | Crystal structure of Myc3 N-terminal JAZ-binding domain [44-238] from Arabidopsis | | Descriptor: | CALCIUM ION, Transcription factor MYC3 | | Authors: | Ke, J, Zhang, F, Zhou, X.E, Brunzelle, J, Zhou, M, Xu, H.E, Melcher, K, He, S.Y. | | Deposit date: | 2014-11-05 | | Release date: | 2015-08-12 | | Last modified: | 2015-09-16 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling.
Nature, 525, 2015
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4RRU
 | | Myc3 N-terminal JAZ-binding domain[5-242] from arabidopsis | | Descriptor: | CALCIUM ION, Transcription factor MYC3 | | Authors: | Ke, J, Zhang, F, Zhou, X.E, Brunzelle, J.S, Zhou, M, Xu, H.E, Melcher, K, He, S.Y. | | Deposit date: | 2014-11-06 | | Release date: | 2015-08-12 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling.
Nature, 525, 2015
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4RS9
 | | Structure of Myc3 N-terminal JAZ-binding domain [44-238] in complex with Jas motif of JAZ9 | | Descriptor: | Protein TIFY 7, Transcription factor MYC3 | | Authors: | Ke, J, Zhang, F, Zhou, X.E, Brunzelle, J.S, Zhou, M, Xu, H.E, Melcher, K, He, S.Y. | | Deposit date: | 2014-11-07 | | Release date: | 2015-08-12 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling.
Nature, 525, 2015
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6UI4
 | | Crystal structure of phenamacril-bound F. graminearum myosin I | | Descriptor: | Calmodulin, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | Authors: | Zhou, Y, Zhou, X.E, Gong, Y, Zhu, Y, Xu, H.E, Zhou, M, Melcher, K, Zhang, F. | | Deposit date: | 2019-09-30 | | Release date: | 2020-03-25 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Structural basis of Fusarium myosin I inhibition by phenamacril.
Plos Pathog., 16, 2020
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7TAK
 | | Structure of a NAT transporter | | Descriptor: | GUANINE, Putative membrane protein PurT | | Authors: | Weng, J, Zhou, X, Ren, Z, Chen, K, Zhou, M. | | Deposit date: | 2021-12-21 | | Release date: | 2023-01-25 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.79828 Å) | | Cite: | Structure of a NAT transporter
To Be Published
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4TQ4
 | | Structure of a UbiA homolog from Archaeoglobus fulgidus bound to DMAPP and Mg2+ | | Descriptor: | DIMETHYLALLYL DIPHOSPHATE, MAGNESIUM ION, prenyltransferase | | Authors: | Huang, H, Levin, E.J, Bai, Y, Zhou, M, New York Consortium on Membrane Protein Structure (NYCOMPS) | | Deposit date: | 2014-06-10 | | Release date: | 2014-07-16 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.5025 Å) | | Cite: | Structure of a Membrane-Embedded Prenyltransferase Homologous to UBIAD1.
Plos Biol., 12, 2014
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