4ZWS
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4ZWT
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2EKE
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6D74
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8EBM
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8EBN
| Structure of KLHDC2-EloB/C tetrameric assembly | Descriptor: | Elongin-B, Elongin-C, Kelch domain-containing protein 2 | Authors: | Scott, D.C, Schulman, B.A. | Deposit date: | 2022-08-31 | Release date: | 2023-02-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | E3 ligase autoinhibition by C-degron mimicry maintains C-degron substrate fidelity. Mol.Cell, 83, 2023
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8EBL
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6NXD
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6NXC
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4HNJ
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4KBL
| Structure of HHARI, a RING-IBR-RING ubiquitin ligase: autoinhibition of an Ariadne-family E3 and insights into ligation mechanism | Descriptor: | E3 ubiquitin-protein ligase ARIH1, ZINC ION | Authors: | Duda, D.M, Olszewski, J.L, Schulman, B.A. | Deposit date: | 2013-04-23 | Release date: | 2013-05-29 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structure of HHARI, a RING-IBR-RING Ubiquitin Ligase: Autoinhibition of an Ariadne-Family E3 and Insights into Ligation Mechanism. Structure, 21, 2013
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4KC9
| Structure of HHARI, a RING-IBR-RING ubiquitin ligase: autoinhibition of an Ariadne-family E3 and insights into ligation mechanism | Descriptor: | E3 ubiquitin-protein ligase ARIH1, ZINC ION | Authors: | Duda, D.M, Olszewski, J.L, Schulman, B.A. | Deposit date: | 2013-04-24 | Release date: | 2013-05-29 | Last modified: | 2013-07-03 | Method: | X-RAY DIFFRACTION (3.603 Å) | Cite: | Structure of HHARI, a RING-IBR-RING Ubiquitin Ligase: Autoinhibition of an Ariadne-Family E3 and Insights into Ligation Mechanism. Structure, 21, 2013
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2LK4
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2M5B
| The NMR structure of the BID-BAK complex | Descriptor: | Bcl-2 homologous antagonist/killer, human_BID_BH3_SAHB | Authors: | Moldoveanu, T, Grace, C.R, Kriwacki, R.W, Green, D.R. | Deposit date: | 2013-02-19 | Release date: | 2013-04-17 | Last modified: | 2023-11-15 | Method: | SOLUTION NMR | Cite: | BID-induced structural changes in BAK promote apoptosis. Nat.Struct.Mol.Biol., 20, 2013
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7N00
| Anaplastic lymphoma kinase (ALK) extracellular fragment of ligand binding region 648-1025 in complex with AUG-alpha | Descriptor: | ALK and LTK ligand 2, ALK tyrosine kinase receptor | Authors: | Reshetnyak, A.V, Myasnikov, A.G, Rossi, P, Miller, D.J, Kalodimos, C.G. | Deposit date: | 2021-05-24 | Release date: | 2021-11-24 | Last modified: | 2021-12-15 | Method: | ELECTRON MICROSCOPY (2.27 Å) | Cite: | Mechanism for the activation of the anaplastic lymphoma kinase receptor. Nature, 600, 2021
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7MZY
| Anaplastic lymphoma kinase (ALK) extracellular fragment of ligand binding region 673-986 | Descriptor: | ACETATE ION, ALK tyrosine kinase receptor | Authors: | Reshetnyak, A.V, Sowaileh, M, Miller, D.J, Rossi, P, Myasnikov, A.G, Kalodimos, C.G. | Deposit date: | 2021-05-24 | Release date: | 2021-11-24 | Last modified: | 2021-12-15 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Mechanism for the activation of the anaplastic lymphoma kinase receptor. Nature, 600, 2021
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7MZZ
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7MZW
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7MZX
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2M04
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2M03
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4XEF
| Pyk2-FAT complexed with Leupaxin LD motif LD1 | Descriptor: | 20-mer peptide containing LD1 motif of leupaxin, Protein-tyrosine kinase 2-beta | Authors: | Miller, D.J. | Deposit date: | 2014-12-23 | Release date: | 2015-12-23 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural Basis for the Interaction between Pyk2-FAT Domain and Leupaxin LD Repeats. Biochemistry, 55, 2016
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4XEV
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4YWM
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4YWK
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