7MZY
Anaplastic lymphoma kinase (ALK) extracellular fragment of ligand binding region 673-986
Summary for 7MZY
| Entry DOI | 10.2210/pdb7mzy/pdb |
| Related | 7MZW 7MZX 7MZZ 7N00 |
| Descriptor | ALK tyrosine kinase receptor, ACETATE ION (3 entities in total) |
| Functional Keywords | anaplastic lymphoma kinase, receptor tyrosine kinases, rtk, fam150, ltk, de novo protein, transferase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 2 |
| Total formula weight | 64697.35 |
| Authors | Reshetnyak, A.V.,Sowaileh, M.,Miller, D.J.,Rossi, P.,Myasnikov, A.G.,Kalodimos, C.G. (deposition date: 2021-05-24, release date: 2021-11-24, Last modification date: 2021-12-15) |
| Primary citation | Reshetnyak, A.V.,Rossi, P.,Myasnikov, A.G.,Sowaileh, M.,Mohanty, J.,Nourse, A.,Miller, D.J.,Lax, I.,Schlessinger, J.,Kalodimos, C.G. Mechanism for the activation of the anaplastic lymphoma kinase receptor. Nature, 600:153-157, 2021 Cited by PubMed: 34819673DOI: 10.1038/s41586-021-04140-8 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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