7MZW

Anaplastic lymphoma kinase (ALK) extracellular ligand binding region 673-1025

Summary for 7MZW

• Entry DOI: 10.2210/pdb7mzw/pdb
• Related: 7MZW 7MZX 7MZY 7MZZ 7N00
• NMR Information: BMRB: 30910
• Descriptor: ALK tyrosine kinase receptor (1 entity in total)
• Functional Keywords: anaplastic lymphoma kinase, receptor tyrosine kinases, rtk, fam150, ltk, de novo protein, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 36452.29

Authors

Rossi, P.,Sowaileh, M.,Reshetnyak, A.V.,Kalodimos, C.G. (deposition date: 2021-05-24, release date: 2021-12-08, Last modification date: 2021-12-15)

• Primary citation: Reshetnyak, A.V.,Rossi, P.,Myasnikov, A.G.,Sowaileh, M.,Mohanty, J.,Nourse, A.,Miller, D.J.,Lax, I.,Schlessinger, J.,Kalodimos, C.G.; Mechanism for the activation of the anaplastic lymphoma kinase receptor.; Nature, 600:153-157, 2021; PubMed: 34819673; DOI: 10.1038/s41586-021-04140-8

Experimental method

SOLUTION NMR