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4F33
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BU of 4f33 by Molmil
Crystal Structure of therapeutic antibody MORAb-009
Descriptor: MORAb-009 FAB heavy chain, MORAb-009 FAB light chain, TETRAETHYLENE GLYCOL
Authors:Xia, D, Ma, J, Tang, W.K, Esser, L.
Deposit date:2012-05-08
Release date:2012-07-11
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.749 Å)
Cite:Recognition of mesothelin by the therapeutic antibody MORAb-009: structural and mechanistic insights.
J.Biol.Chem., 287, 2012
4F3F
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BU of 4f3f by Molmil
Crystal Structure of Msln7-64 MORAb-009 FAB complex
Descriptor: MORAb-009 Fab heavy chain, MORAb-009 Fab light chain, Mesothelin
Authors:Xia, D, Pastan, I, Ma, J, Tang, W.K, Esser, L.
Deposit date:2012-05-09
Release date:2012-07-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Recognition of mesothelin by the therapeutic antibody MORAb-009: structural and mechanistic insights.
J.Biol.Chem., 287, 2012
7L1C
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BU of 7l1c by Molmil
Crystal structure of HLA-A*03:01 in complex with a mutant PIK3CA peptide
Descriptor: Beta-2-microglobulin, FORMIC ACID, GLYCEROL, ...
Authors:Ma, J, Baker, B.M.
Deposit date:2020-12-14
Release date:2022-03-23
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Immunogenicity and therapeutic targeting of a public neoantigen derived from mutated PIK3CA.
Nat Med, 28, 2022
7L1D
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BU of 7l1d by Molmil
Crystal structure of human 21LT2-2 TCR bound to HLA-A*03:01 in complex with a mutant PIK3CA peptide
Descriptor: ACETATE ION, Beta-2-microglobulin, GLYCEROL, ...
Authors:Ma, J, Baker, B.M.
Deposit date:2020-12-14
Release date:2022-03-23
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Immunogenicity and therapeutic targeting of a public neoantigen derived from mutated PIK3CA.
Nat Med, 28, 2022
7L1B
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BU of 7l1b by Molmil
Crystal structure of HLA-A*03:01 in complex with a wild-type PIK3CA peptide
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Ma, J, Baker, B.M.
Deposit date:2020-12-14
Release date:2022-03-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Immunogenicity and therapeutic targeting of a public neoantigen derived from mutated PIK3CA.
Nat Med, 28, 2022
5X9C
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BU of 5x9c by Molmil
Crystal structure of the cytosolic domain of human MiD51
Descriptor: Mitochondrial dynamics protein MID51
Authors:Sun, F, Pang, X, Ma, J.
Deposit date:2017-03-06
Release date:2018-03-21
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:New interfaces on MiD51 for Drp1 recruitment and mitochondrial fission regulation
To Be Published
5X9B
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BU of 5x9b by Molmil
Crystal structure of the cytosolic domain of human MiD51
Descriptor: Mitochondrial dynamics protein MID51
Authors:Sun, F, Pang, X, Ma, J.
Deposit date:2017-03-06
Release date:2018-04-25
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:New interfaces on MiD51 for Drp1 recruitment and regulation.
Plos One, 14, 2019
6AKM
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BU of 6akm by Molmil
Crystal structure of SLMAP-SIKE1 complex
Descriptor: GLYCEROL, Sarcolemmal membrane-associated protein, Suppressor of IKBKE 1
Authors:Ma, J, Chen, M, Zhou, Z.C.
Deposit date:2018-09-02
Release date:2019-01-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Architecture, substructures, and dynamic assembly of STRIPAK complexes in Hippo signaling.
Cell Discov, 5, 2019
7VH2
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BU of 7vh2 by Molmil
Cryo-EM structure of Machupo virus dimeric polymerase L
Descriptor: RNA-directed RNA polymerase L
Authors:Zhang, X, Ma, J, Zhang, S.
Deposit date:2021-09-20
Release date:2021-09-29
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (5.1 Å)
Cite:Structure of Machupo virus polymerase in complex with matrix protein Z.
Nat Commun, 12, 2021
7VGQ
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BU of 7vgq by Molmil
Cryo-EM structure of Machupo virus polymerase L in complex with matrix protein Z
Descriptor: Maltose/maltodextrin-binding periplasmic protein,RING finger protein Z, RNA-directed RNA polymerase L, ZINC ION
Authors:Zhang, X, Ma, J, Zhang, S.
Deposit date:2021-09-18
Release date:2021-09-29
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structure of Machupo virus polymerase in complex with matrix protein Z.
Nat Commun, 12, 2021
7VH1
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BU of 7vh1 by Molmil
Cryo-EM structure of Machupo virus dimeric L-Z complex
Descriptor: Maltose/maltodextrin-binding periplasmic protein,RING finger protein Z, RNA-directed RNA polymerase L, ZINC ION
Authors:Zhang, X, Ma, J, Zhang, S.
Deposit date:2021-09-20
Release date:2021-09-29
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structure of Machupo virus polymerase in complex with matrix protein Z.
Nat Commun, 12, 2021
7EE2
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BU of 7ee2 by Molmil
Structural insights into the substrate-binding mechanism of a glycoside hydrolase family 12 beta-1,3-1,4-glucanase from Chaetomium sp.CQ31
Descriptor: GLYCEROL, glycoside hydrolase family 12 beta-1,3-1,4-glucanase
Authors:Jiang, Z.Q, Ma, J.
Deposit date:2021-03-17
Release date:2022-03-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.37011635 Å)
Cite:Structural and biochemical insights into the substrate-binding mechanism of a glycoside hydrolase family 12 beta-1,3-1,4-glucanase from Chaetomium sp.
J.Struct.Biol., 213, 2021
3JUE
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BU of 3jue by Molmil
Crystal Structure of ArfGAP and ANK repeat domain of ACAP1
Descriptor: ARFGAP with coiled-coil, ANK repeat and PH domain-containing protein 1, SULFATE ION, ...
Authors:Pang, X, Zhang, K, Ma, J, Zhou, Q, Sun, F.
Deposit date:2009-09-15
Release date:2010-09-22
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mechanistic insights into regulated cargo binding by ACAP1 protein
J.Biol.Chem., 287, 2012
3BT6
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BU of 3bt6 by Molmil
Crystal Structure of Influenza B Virus Hemagglutinin
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Wang, Q, Cheng, F, Lu, M, Tian, X, Ma, J.
Deposit date:2007-12-27
Release date:2008-05-27
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of unliganded influenza B virus hemagglutinin.
J.Virol., 82, 2008
4R4X
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BU of 4r4x by Molmil
Structure of PNGF-II in C2 space group
Descriptor: PNGF-II, ZINC ION
Authors:Sun, G, Yu, X, Celimuge, Wang, L, Li, M, Gan, J, Qu, D, Ma, J, Chen, L.
Deposit date:2014-08-20
Release date:2015-01-28
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Identification and Characterization of a Novel Prokaryotic Peptide: N-glycosidase from Elizabethkingia meningoseptica
J.Biol.Chem., 2015
4ZWJ
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BU of 4zwj by Molmil
Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser
Descriptor: Chimera protein of human Rhodopsin, mouse S-arrestin, and T4 Endolysin
Authors:Kang, Y, Zhou, X.E, Gao, X, He, Y, Liu, W, Ishchenko, A, Barty, A, White, T.A, Yefanov, O, Han, G.W, Xu, Q, de Waal, P.W, Ke, J, Tan, M.H.E, Zhang, C, Moeller, A, West, G.M, Pascal, B, Eps, N.V, Caro, L.N, Vishnivetskiy, S.A, Lee, R.J, Suino-Powell, K.M, Gu, X, Pal, K, Ma, J, Zhi, X, Boutet, S, Williams, G.J, Messerschmidt, M, Gati, C, Zatsepin, N.A, Wang, D, James, D, Basu, S, Roy-Chowdhury, S, Conrad, C, Coe, J, Liu, H, Lisova, S, Kupitz, C, Grotjohann, I, Fromme, R, Jiang, Y, Tan, M, Yang, H, Li, J, Wang, M, Zheng, Z, Li, D, Howe, N, Zhao, Y, Standfuss, J, Diederichs, K, Dong, Y, Potter, C.S, Carragher, B, Caffrey, M, Jiang, H, Chapman, H.N, Spence, J.C.H, Fromme, P, Weierstall, U, Ernst, O.P, Katritch, V, Gurevich, V.V, Griffin, P.R, Hubbell, W.L, Stevens, R.C, Cherezov, V, Melcher, K, Xu, H.E, GPCR Network (GPCR)
Deposit date:2015-05-19
Release date:2015-07-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.302 Å)
Cite:Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser.
Nature, 523, 2015
7VF5
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BU of 7vf5 by Molmil
Human m6A-METTL associated complex (WTAP, VIRMA, and HAKAI)
Descriptor: Pre-mRNA-splicing regulator WTAP, Protein virilizer homolog
Authors:Su, S, Li, S, Deng, T, Gao, M, Yin, Y, Wu, B, Peng, C, Liu, J, Ma, J, Zhang, K.
Deposit date:2021-09-10
Release date:2022-09-14
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Cryo-EM structures of human m6A writer complexes.
Cell Res., 32, 2022
7VF2
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BU of 7vf2 by Molmil
Human m6A-METTL associated complex (WTAP, VIRMA, ZC3H13, and HAKAI)
Descriptor: Pre-mRNA-splicing regulator WTAP, Protein virilizer homolog, Zinc finger CCCH domain-containing protein 13
Authors:Su, S, Li, S, Deng, T, Gao, M, Yin, Y, Wu, B, Peng, C, Liu, J, Ma, J, Zhang, K.
Deposit date:2021-09-10
Release date:2022-09-14
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Cryo-EM structures of human m6A writer complexes.
Cell Res., 32, 2022
6Y8K
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BU of 6y8k by Molmil
Crystal structure of CD137 in complex with the cyclic peptide BCY10916
Descriptor: 1,1',1''-(1,3,5-triazinane-1,3,5-triyl)tripropan-1-one, 1,2-ETHANEDIOL, ACETATE ION, ...
Authors:Upadhyaya, P, Kublin, J, Dods, R, Kristensson, J, Lahdenranta, J, Kleyman, M, Repash, E, Ma, J, Mudd, G, Van Rietschoten, K, Haines, E, Harrison, H, Beswick, P, Chen, L, McDonnell, K, Battula, S, Hurov, K, Keen, N.
Deposit date:2020-03-05
Release date:2021-02-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.011 Å)
Cite:Anticancer immunity induced by a synthetic tumor-targeted CD137 agonist.
J Immunother Cancer, 9, 2021
4CKH
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BU of 4ckh by Molmil
Helical reconstruction of ACAP1(BAR-PH domain) decorated membrane tubules by cryo-electron microscopy
Descriptor: ARF-GAP WITH COILED-COIL, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1
Authors:Pang, X.Y, Fan, J, Zhang, Y, Zhang, K, Gao, B.Q, Ma, J, Li, J, Deng, Y.C, Zhou, Q.J, Hsu, V, Sun, F.
Deposit date:2014-01-06
Release date:2014-10-15
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (17 Å)
Cite:A Ph Domain in Acap1 Possesses Key Features of the Bar Domain in Promoting Membrane Curvature.
Dev.Cell, 31, 2014
6X9H
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BU of 6x9h by Molmil
Molecular mechanism and structural basis of small-molecule modulation of acid-sensing ion channel 1 (ASIC1)
Descriptor: 2-[4-(3,4-dimethoxyphenoxy)phenyl]-1H-benzimidazole-6-carboximidamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, ...
Authors:Liu, Y, Ma, J, DesJarlais, R.L, Hagan, R, Rech, J, Lin, D, Liu, C, Miller, R, Schoellerman, J, Luo, J, Letavic, M, Grasberger, B, Maher, M.
Deposit date:2020-06-02
Release date:2020-12-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Molecular mechanism and structural basis of small-molecule modulation of the gating of acid-sensing ion channel 1.
Commun Biol, 4, 2021
4CKG
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BU of 4ckg by Molmil
Helical reconstruction of ACAP1(BAR-PH domain) decorated membrane tubules by cryo-electron microscopy
Descriptor: ARF-GAP WITH COILED-COIL, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1
Authors:Pang, X.Y, Fan, J, Zhang, Y, Zhang, K, Gao, B.Q, Ma, J, Li, J, Deng, Y.C, Zhou, Q.J, Hsu, V, Sun, F.
Deposit date:2014-01-06
Release date:2014-10-15
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (15 Å)
Cite:A Ph Domain in Acap1 Possesses Key Features of the Bar Domain in Promoting Membrane Curvature.
Dev.Cell, 31, 2014
1ZQ3
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BU of 1zq3 by Molmil
NMR Solution Structure of the Bicoid Homeodomain Bound to the Consensus DNA Binding Site TAATCC
Descriptor: 5'-D(*CP*GP*GP*GP*GP*AP*TP*TP*AP*GP*AP*GP*C)-3', 5'-D(*GP*CP*TP*CP*TP*AP*AP*TP*CP*CP*CP*CP*G)-3', Homeotic bicoid protein
Authors:Baird-Titus, J.M, Rance, M, Clark-Baldwin, K, Ma, J, Vrushank, D.
Deposit date:2005-05-18
Release date:2006-02-14
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The solution structure of the native K50 Bicoid homeodomain bound to the consensus TAATCC DNA-binding site.
J.Mol.Biol., 356, 2006
3CM8
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BU of 3cm8 by Molmil
A RNA polymerase subunit structure from virus
Descriptor: Polymerase acidic protein, peptide from RNA-directed RNA polymerase catalytic subunit
Authors:He, X, Zhou, J, Zeng, Z, Ma, J, Zhang, R, Rao, Z, Liu, Y.
Deposit date:2008-03-21
Release date:2008-07-15
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.899 Å)
Cite:Crystal structure of the polymerase PAC-PB1N complex from an avian influenza H5N1 virus
Nature, 454, 2008
5X58
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BU of 5x58 by Molmil
Prefusion structure of SARS-CoV spike glycoprotein, conformation 1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Yuan, Y, Cao, D, Zhang, Y, Ma, J, Qi, J, Wang, Q, Lu, G, Wu, Y, Yan, J, Shi, Y, Zhang, X, Gao, G.F.
Deposit date:2017-02-15
Release date:2017-05-03
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains
Nat Commun, 8, 2017

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